{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:10:32Z","timestamp":1791198632591,"version":"4.1.0"},"reference-count":33,"publisher":"American Chemical Society (ACS)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acc. Chem. Res."],"published-print":{"date-parts":[[2009,7,21]]},"DOI":"10.1021\/ar800215p","type":"journal-article","created":{"date-parts":[[2009,6,24]],"date-time":"2009-06-24T16:31:31Z","timestamp":1245861091000},"page":"958-968","source":"Crossref","is-referenced-by-count":83,"title":["Peptide-Targeted Diagnostics and Radiotherapeutics"],"prefix":"10.1021","volume":"42","author":[{"given":"Michael F.","family":"Tweedle","sequence":"first","affiliation":[{"name":"Departments of Radiology, Chemistry, and Pharmacy; The Ohio State University; Biomedical Research Tower; 460 West 12th Avenue, Columbus, Ohio 43215"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2009,6,24]]},"reference":[{"key":"ref1\/cit1","unstructured":"Tweedle, M. F., Gaughan, G., and Hagan, J.1-Substituted-1,4,7, triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs. U.S. Patent No. 4,885,363, 1989."},{"key":"ref2\/cit2","unstructured":"Gries, H., Rosenberg, D., and Weinman, H.J.Diagnostic media. U.S. Patent No. 4,647,447, 1987."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0020-1693(00)94512-2","volume":"94","author":"Desreux J. F.","year":"1984","journal-title":"Inorg. Chim. Acta"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1021\/ic00253a038","volume":"26","author":"Cacheris W. P.","year":"1987","journal-title":"Inorg. Chem."},{"key":"ref5\/cit5","volume-title":"The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging","author":"Merbach A. E.","year":"2001"},{"key":"ref7\/cit7a","first-page":"1144","volume":"47","author":"Lantry L. E.","year":"2006","journal-title":"J. Nucl. Med."},{"key":"ref7\/cit7b","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/j.apradiso.2007.11.007","volume":"66","author":"Chen J.","year":"2008","journal-title":"Appl. Radiat. Isotopes"},{"key":"ref7\/cit7c","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00259-006-0229-9","volume":"34","author":"Waser B.","year":"2007","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"ref7\/cit7d","first-page":"310","volume":"50","author":"Panigone S.","year":"2006","journal-title":"Q. J. Nucl. Med. Mol. Imaging"},{"key":"ref7\/cit7e","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s10585-008-9220-0","volume":"26","author":"Thomas R.","year":"2009","journal-title":"Clin. Exp. Metastasis"},{"key":"ref8\/cit8","unstructured":"Swenson, R. E.; Lattuada, L.; Linder, K. E.; Capalleti, E.; Raju, N.; Chen, J.; Lantry, L. E.; Thoma, R.; Arunachalum, T.; Maddelena, M. E.; Fox, J. S.; Nunn, A. D.; Tweedle, M. F.Optimization of the linker between the metal chelate and the targeting peptide provided the superior properties of 177Lu-AMBA, a GRP radiotherapeutic in clinical development, Presented at the 236th ACS meeting, 2008, abstract no. 387."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0969-8051(02)00391-8","volume":"30","author":"Smith C. J.","year":"2003","journal-title":"Nucl. Med. Biol."},{"key":"ref10\/cit10","author":"Linder K. E.","journal-title":"Bioconjugate Chem."},{"key":"ref11\/cit11","unstructured":"Bodei, L.; Ferrari, M.; Nunn, A.; Llull, J. B.; Cremonesi, M.; Martano, L.; Laurora, G.; Scardino, E.; Tiberini, S.; Bufi, G.; Eaton, S.; De Cobelli, O.; Paganelli, G.Presented at the European Association for Nuclear Medicine meeting, 2007, Copenhagen."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1021\/ic802328a","volume":"48","author":"Cagnolini A.","year":"2009","journal-title":"Inorg. Chem."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"4193","DOI":"10.1021\/ic00072a008","volume":"32","author":"Kumar K.","year":"1993","journal-title":"Inorg. Chem."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1021\/bp010181o","volume":"18","author":"Sato A. K.","year":"2002","journal-title":"Biotechnol. Prog."},{"key":"ref14\/cit14a","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1021\/bp010181o","volume":"18","author":"Enright J.","year":"2002","journal-title":"Biotechnol. Prog."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/nrc2403","volume":"8","author":"Ellis L. M.","year":"2008","journal-title":"Nat. Rev. Cancer"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1093\/protein\/gzi049","volume":"18","author":"Shrivastava A.","year":"2005","journal-title":"Protein Eng., Des. Sel."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1002\/bip.20570","volume":"84","author":"Pillai R.","year":"2006","journal-title":"Pept. Sci."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0092-8674(00)80456-0","volume":"91","author":"Wiesmann C.","year":"1997","journal-title":"Cell"},{"key":"ref19\/cit19a","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0169-409X(98)00104-5","volume":"37","author":"Klibanov A. L.","year":"1999","journal-title":"Adv. Drug Delivery Rev."},{"key":"ref19\/cit19b","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.nuclcard.2007.09.008","volume":"14","author":"Klibanov A. L.","year":"2007","journal-title":"J. Nucl. Cardiol."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"5702","DOI":"10.1074\/jbc.M511941200","volume":"281","author":"von Wronski M.","year":"2006","journal-title":"J. Biol. Chem."},{"key":"ref21\/cit21","first-page":"154","volume":"42","author":"Caveliers V.","year":"2001","journal-title":"J. Nucl. Med."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.tetlet.2005.01.026","volume":"46","author":"Raju N.","year":"2005","journal-title":"Tetrahedron Lett."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/cmmi.91","volume":"1","author":"Tweedle M. F.","year":"2006","journal-title":"Contrast Media Mol. Imaging"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"6152","DOI":"10.1073\/pnas.0700043104","volume":"104","author":"Vander Kooi C. W.","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s10456-008-9097-1","volume":"11","author":"Geretti E.","year":"2008","journal-title":"Angiogenesis"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"24049","DOI":"10.1074\/jbc.M703554200","volume":"282","author":"Pan Q.","year":"2007","journal-title":"J. Biol. Chem."},{"key":"ref27\/cit27","unstructured":"von Wronski, M.; Raju, N.; Bogdan, N. J.; Fox, J.; Lantry, L. E.; Tweedle, M. F.; Nunn, A. D.Anti-neuropilin-1 antibodies block the binding of a tuftsin-antagonist peptide, TKPPR, to neuropilin-1 in mice and on receptor-positive cells, Presented at the Joint Molecular Imaging Conference, 2007, abstract no. 0164."},{"key":"ref28\/cit28","unstructured":"Von Wronski, M.; Raju, N.; Tweedle, M. F.; Nunn, A. D.Subcellular localization of neuropilin-1 on endothelial cells with peptide-targeted quantum dots, Presented at the American Association for Cancer Research meeting, 2008, abstract no. LB-197."}],"container-title":["Accounts of Chemical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ar800215p","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T05:59:06Z","timestamp":1678168746000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ar800215p"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6,24]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2009,7,21]]}},"alternative-id":["10.1021\/ar800215p"],"URL":"https:\/\/doi.org\/10.1021\/ar800215p","relation":{},"ISSN":["0001-4842","1520-4898"],"issn-type":[{"value":"0001-4842","type":"print"},{"value":"1520-4898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6,24]]}}}