{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:10:16Z","timestamp":1760782216809},"reference-count":37,"publisher":"American Chemical Society (ACS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioconjugate Chem."],"published-print":{"date-parts":[[2000,9,1]]},"DOI":"10.1021\/bc0000280","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T05:51:32Z","timestamp":1027662692000},"page":"714-724","source":"Crossref","is-referenced-by-count":13,"title":["Linker-Mediated Modulation of the Chemiluminescent Signal from <i>N<\/i><sup>10<\/sup>-(3-Sulfopropyl)-<i>N<\/i>-sulfonylacridinium-9-carboxamide Tracers"],"prefix":"10.1021","volume":"11","author":[{"given":"Maciej","family":"Adamczyk","sequence":"first","affiliation":[{"name":"Abbott Laboratories, Diagnostics Division, Department of Chemistry D9NM, Building AP 20, 100 Abbott Park Road, Abbott Park, Illinois 60064-6016"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yon-Yih","family":"Chen","sequence":"additional","affiliation":[{"name":"Abbott Laboratories, Diagnostics Division, Department of Chemistry D9NM, Building AP 20, 100 Abbott Park Road, Abbott Park, Illinois 60064-6016"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey R.","family":"Fishpaugh","sequence":"additional","affiliation":[{"name":"Abbott Laboratories, Diagnostics Division, Department of Chemistry D9NM, Building AP 20, 100 Abbott Park Road, Abbott Park, Illinois 60064-6016"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phillip G.","family":"Mattingly","sequence":"additional","affiliation":[{"name":"Abbott Laboratories, Diagnostics Division, Department of Chemistry D9NM, Building AP 20, 100 Abbott Park Road, Abbott Park, Illinois 60064-6016"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You","family":"Pan","sequence":"additional","affiliation":[{"name":"Abbott Laboratories, Diagnostics Division, Department of Chemistry D9NM, Building AP 20, 100 Abbott Park Road, Abbott Park, Illinois 60064-6016"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Shreder","sequence":"additional","affiliation":[{"name":"Abbott Laboratories, Diagnostics Division, Department of Chemistry D9NM, Building AP 20, 100 Abbott Park Road, Abbott Park, Illinois 60064-6016"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiguang","family":"Yu","sequence":"additional","affiliation":[{"name":"Abbott Laboratories, Diagnostics Division, Department of Chemistry D9NM, Building AP 20, 100 Abbott Park Road, Abbott Park, Illinois 60064-6016"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2000,7,19]]},"reference":[{"key":"bc0000280b00001\/bc0000280b00001_1","volume-title":"An improved label for amphetamine fluoroimmunoassay. Ther. Drug Monit. 11, 607\u221211","author":"Gallacher G.","year":"1989"},{"key":"bc0000280b00002\/bc0000280b00002_1","volume-title":"A chemical approach to solving bridging phenomena in steroid radioimmunoassays. Steroids 38, 161\u221273","author":"Nordblom G. D.","year":"1981"},{"key":"bc0000280b00003\/bc0000280b00003_1","volume-title":"A specific radioimmunoassay for androstenedione with reduced bridge-binding. Steroids 44, 275\u221282","author":"Nordblom G. D.","year":"1984"},{"key":"bc0000280b00004\/bc0000280b00004_1","doi-asserted-by":"crossref","DOI":"10.1016\/0022-4731(89)90260-4","volume":"32","author":"Tiefenauer L. X.","year":"1989","journal-title":"J. Steroid Biochem."},{"key":"bc0000280b00005\/bc0000280b00005_1","volume-title":"The use of homologous and heterologous 125I-radioligands in the radioimmunoassay of progesterone. Steroids 32, 467\u221286","author":"Allen R. M.","year":"1978"},{"key":"bc0000280b00006\/bc0000280b00006_1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0003-2670(93)80278-S","volume":"275","author":"De Boever J.","year":"1993","journal-title":"Anal. Chim. Acta"},{"key":"bc0000280b00007\/bc0000280b00007_1","doi-asserted-by":"crossref","DOI":"10.1021\/ja9732542","volume":"120","author":"Ersoy O.","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"bc0000280b00008\/bc0000280b00008_1","volume-title":"Basic studies on heterobifunctional biotin-PEG conjugates with a 3-(4-pyridyldithio)propionyl marker on the 2nd terminus. Bioconjugate Chem. 8, 545\u221251","author":"Kaiser K.","year":"1997"},{"key":"bc0000280b00009\/bc0000280b00009_1","volume-title":"7-\u03b1-Biotinylated testosterone derivatives as tracers for a competitive chemiluminescence immunoassay of testosterone in serum. Clin. Chem. 43, 2345\u221252","author":"Luppa P.","year":"1997"},{"key":"bc0000280b00010\/bc0000280b00010_1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/0022-4731(87)90128-2","volume":"28","author":"Mitsuma M.","year":"1987","journal-title":"J. Steroid Biochem."},{"key":"bc0000280b00011\/bc0000280b00011_1","doi-asserted-by":"crossref","DOI":"10.1016\/0022-1759(84)90296-5","volume":"74","author":"Tiefenauer L. X.","year":"1984","journal-title":"J. Immunol. Methods"},{"key":"bc0000280b00012\/bc0000280b00012_1","volume-title":"Fluorescence energy-transfer cyanine heterodimers with high affinity for double-stranded DNA. I. Synthesis and spectroscopic properties. Anal. Biochem. 231, 247\u221255","author":"Benson S. C.","year":"1995"},{"key":"bc0000280b00013\/bc0000280b00013_1","volume-title":"Biotin-fluorophore conjugates with poly(ethylene glycol) spacers retain intense fluorescence after binding to avidin and streptavidin. Bioconjugate Chem. 8, 552\u22129","author":"Gruber H. J.","year":"1997"},{"key":"bc0000280b00014\/bc0000280b00014_1","volume-title":"Heterobifunctional cross-linkers containing 4,9-dioxa-1, 12-dodecanediamine spacers. Bioconjugate Chem. 8, 447\u221252","author":"Johnson G. M.","year":"1997"},{"key":"bc0000280b00015\/bc0000280b00015_1","volume":"56","author":"Lown J. W.","year":"1978","journal-title":"Can. J. Biochem."},{"key":"bc0000280b00016\/bc0000280b00016_1","volume-title":"Biotin-pyrene conjugates with poly(ethylene glycol) spacers are convenient fluorescent-probes for avidin and streptavidin. Bioconjugate Chem. 8, 560\u22126","author":"Marek M.","year":"1997"},{"key":"bc0000280b00017\/bc0000280b00017_1","volume-title":"Stability, specificity and fluorescence brightness of multiply labeled fluorescent DNA probes. Nucleic Acids Res. 25, 2923\u22129","author":"Randolph J. B.","year":"1997"},{"key":"bc0000280b00018\/bc0000280b00018_1","volume-title":"Vitamin B12 mediated oral delivery systems for GCSF and EPO. Bioconjugate Chem. 6, 459\u221265","author":"Russell-Jones G. J.","year":"1995"},{"key":"bc0000280b00019\/bc0000280b00019_1","first-page":"548","author":"Russell-Jones G. J.","year":"1996","journal-title":"Patent U."},{"key":"bc0000280b00020\/bc0000280b00020_1","volume-title":"Monoadduct forming photochemical reagents for labeling nucleic acids for hybridization. Nucleic Acids Res. 17, 4293\u2212308","author":"Albarella J. P.","year":"1989"},{"key":"bc0000280b00021\/bc0000280b00021_1","volume":"31","author":"Gildea B. D.","year":"1990","journal-title":"Tetrahedron Lett."},{"key":"bc0000280b00022\/bc0000280b00022_1","volume-title":"Heterobifunctional trityl derivatives as linking reagents for the recovery of nucleic acids after labeling and immobilization. Tetrahedron 51, 3793\u2212802","author":"Leikauf E.","year":"1995"},{"key":"bc0000280b00023\/bc0000280b00023_1","volume-title":"Preparation of oligonucleotide-biotin conjugates with cleavable linkers. Bioconjugate Chem. 6, 135\u22128","author":"Soukup G. A.","year":"1995"},{"key":"bc0000280b00024\/bc0000280b00024_1","volume-title":"Photocleavable aminotag phosphoramidites for 5\u2018-termini dna\/rna. Nucleic Acids Res. 26, 3572\u22126","author":"Olejnik J.","year":"1998"},{"key":"bc0000280b00025\/bc0000280b00025_1","doi-asserted-by":"crossref","DOI":"10.1021\/jo980047r","volume":"63","author":"Adamczyk M.","year":"1998","journal-title":"J. Org. Chem."},{"key":"bc0000280b00026\/bc0000280b00026_1","volume-title":"Modulation of the chemiluminescent signal from N10-(3-sulfopropyl)-N-sulfonylacridinium-9-carboxamides. Tetrahedron 55, 10899\u2212914","author":"Adamczyk M.","year":"1999"},{"key":"bc0000280b00027\/bc0000280b00027_1","doi-asserted-by":"crossref","unstructured":"Adamczyk, M., Fishpaugh, J. R., Gebler, J. C., Mattingly, P. G., and Shreder, K. (1998) Detection of reaction intermediates by flow injection electrospray ionization mass spectrometry:\u2009 reaction of chemiluminescentN-sulfonylacridinium-9-carboxamides with hydrogen peroxide.Eur. Mass Spec.4, 121\u22125.","DOI":"10.1255\/ejms.198"},{"key":"bc0000280b00028\/bc0000280b00028_1","volume-title":"Clinical evaluation of the Abbott TDx fluorescence polarization immunoassay analyzer. Ther. Drug Monit. 6, 360\u22127","author":"Oeltgen P. R.","year":"1984"},{"key":"bc0000280b00029\/bc0000280b00029_1","doi-asserted-by":"crossref","DOI":"10.1016\/0022-1759(85)90253-4","volume":"83","author":"Takayasu S.","year":"1985","journal-title":"J. Immunol. Methods"},{"key":"bc0000280b00030\/bc0000280b00030_1","volume":"111","author":"Dasgupta A.","year":"1999","journal-title":"Am. J. Clin. Pathol."},{"key":"bc0000280b00031\/bc0000280b00031_1","doi-asserted-by":"crossref","DOI":"10.1097\/00007691-199704000-00013","volume-title":"Analytical performance of a new chemiluminescent phenytoin (ACS:180) assay. Ther. Drug Monit. 19, 191\u22124","author":"Dasgupta A.","year":"1997"},{"key":"bc0000280b00032\/bc0000280b00032_1","volume-title":"Adaptation of total phenytoin reagent pack for measuring free phenytoin levels with the Abbott AxSYM immunoassay analyzer. Ther. Drug Monit. 21, 134\u22126","author":"Jarzabek J. I.","year":"1999"},{"key":"bc0000280b00033\/bc0000280b00033_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0960-894X(00)80068-2","volume":"4","author":"Hudkins R. L.","year":"1994","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"bc0000280b00034\/bc0000280b00034_1","volume-title":"Bull. Chem. Soc. Jpn. 38","author":"Sakaibara S.","year":"1965"},{"key":"bc0000280b00035\/bc0000280b00035_1","volume-title":"IgG2a and IgG2b immunoglobulins from mouse serum using protein A-Sepharose. Immunochemistry 15, 429\u221236.","author":"Ey P. L.","year":"1978"},{"key":"bc0000280b00036\/bc0000280b00036_1","volume-title":"Concentrations of binding protein and labeled analyte that are appropriate for measuring at any analyte concentration range in radioimmunoassays. Methods Enzymol. 74, 481\u221297","author":"Halfman C. J.","year":"1981"},{"key":"bc0000280n00001\/bc0000280n00001_1","volume-title":"immunoglobulin G","author":"Abbreviations G"}],"container-title":["Bioconjugate Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bc0000280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T15:58:03Z","timestamp":1679587083000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bc0000280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7,19]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2000,9,1]]}},"alternative-id":["10.1021\/bc0000280"],"URL":"https:\/\/doi.org\/10.1021\/bc0000280","relation":{},"ISSN":["1043-1802","1520-4812"],"issn-type":[{"value":"1043-1802","type":"print"},{"value":"1520-4812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,7,19]]}}}