{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:51:11Z","timestamp":1790855471973,"version":"4.1.0"},"reference-count":34,"publisher":"American Chemical Society (ACS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioconjugate Chem."],"published-print":{"date-parts":[[2001,9,1]]},"DOI":"10.1021\/bc010032r","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T04:41:36Z","timestamp":1027658496000},"page":"798-806","source":"Crossref","is-referenced-by-count":15,"title":["Biological Evaluation of Ring- and Side-Chain-Substituted <i>m<\/i>-Iodobenzylguanidine Analogues"],"prefix":"10.1021","volume":"12","author":[{"given":"Ganesan","family":"Vaidyanathan","sequence":"first","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sriram","family":"Shankar","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna J.","family":"Affleck","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip C.","family":"Welsh","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan K.","family":"Slade","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Zalutsky","sequence":"additional","affiliation":[{"name":"Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2001,8,18]]},"reference":[{"key":"bc010032rb00001\/bc010032rb00001_1","volume":"16","author":"Balley D. M.","year":"1973","journal-title":"J. Med. Chem."},{"key":"bc010032rb00002\/bc010032rb00002_1","volume-title":"Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res. 33, 2643\u22122652","author":"Biedler J. N.","year":"1973"},{"key":"bc010032rb00003\/bc010032rb00003_1","volume":"34","author":"Clerc J.","year":"1993","journal-title":"J. Nucl. Med."},{"key":"bc010032rb00004\/bc010032rb00004_1","volume":"38","author":"Farahati J.","year":"1997","journal-title":"J. Nucl. Med."},{"key":"bc010032rb00005\/bc010032rb00005_1","volume":"24","author":"Fielden R.","year":"1965","journal-title":"Br. J. Pharmacol."},{"key":"bc010032rb00006\/bc010032rb00006_1","volume-title":"Comparative tissue distribution in mice of the alpha-emitter 211At and 131I as labels of a monoclonal antibody and F(ab\u2018)2 fragment. Cancer Res. 50, 3514\u22123520","author":"Garg P. K.","year":"1990"},{"key":"bc010032rb00007\/bc010032rb00007_1","volume-title":"Nigrosin as a dye for differentiating live and dead ascites cells. Exp. Cell Res. 15, 112\u2212117","author":"Kaltenbach J. P.","year":"1958"},{"key":"bc010032rb00008\/bc010032rb00008_1","first-page":"90","volume":"72","author":"Larsen R. H.","year":"1997","journal-title":"Int. J. Radiat. Biol."},{"key":"bc010032rb00009\/bc010032rb00009_1","doi-asserted-by":"crossref","DOI":"10.1002\/ijc.2910470119","volume":"47","author":"Lashford L. S.","year":"1991","journal-title":"Int. J. Cancer"},{"key":"bc010032rb00010\/bc010032rb00010_1","volume":"27","author":"Lee H.","year":"1986","journal-title":"J. Nucl. Med."},{"key":"bc010032rb00011\/bc010032rb00011_1","first-page":"44","volume":"27","author":"Mangner T. J.","year":"1986","journal-title":"J. Nucl. Med."},{"key":"bc010032rb00012\/bc010032rb00012_1","volume-title":"No-carrier-added 123I-MIBG:\u2009 An initial clinical study in patients with phaeochromocytoma. Nucl. Med. Commun. 21, 437\u2212440","author":"Owens J.","year":"2000"},{"key":"bc010032rb00013\/bc010032rb00013_1","volume-title":"Microsomal metabolism of fluoroanilines. Xenobiotica 19, 1297\u22121305","author":"Rietjens I. M.","year":"1989"},{"key":"bc010032rb00014\/bc010032rb00014_1","doi-asserted-by":"crossref","unstructured":"Samnick, S., Bader, J. B., M\u00fcller, M., Chapot, C., Richter, S., Schaefer, A., Sax, B., and Kirsch, C.M. (1999) Improved labeling of no-carrier-added123I-MIBG and preliminary clinical evaluation in patients with ventricular arrhythmias.Nucl. Med. Commun. 20, 537\u2212545.","DOI":"10.1097\/00006231-199906000-00008"},{"key":"bc010032rb00015\/bc010032rb00015_1","doi-asserted-by":"crossref","DOI":"10.1021\/jm00317a017","volume":"10","author":"Short J. H.","year":"1967","journal-title":"J. Med. Chem."},{"key":"bc010032rb00016\/bc010032rb00016_1","volume":"27","author":"Shulkin B. L.","year":"1986","journal-title":"J. Nucl. Med."},{"key":"bc010032rb00017\/bc010032rb00017_1","first-page":"103","volume":"1","author":"Sisson J. C.","year":"1986","journal-title":"Am. J. Physiol. Imaging"},{"key":"bc010032rb00018\/bc010032rb00018_1","volume":"43","author":"Sisson J. C.","year":"1999","journal-title":"Q. J. Nucl. Med."},{"key":"bc010032rb00019\/bc010032rb00019_1","volume-title":"1-(m-[211At]Astatobenzyl)guanidine:\u2009 Synthesis via astatodemetalation and preliminary in vitro and in vivo evaluation. Bioconjugate Chem. 3, 499\u2212503","author":"Vaidyanathan G.","year":"1992"},{"key":"bc010032rb00020\/bc010032rb00020_1","volume-title":"No-carrier-added synthesis of meta-[131I]iodobenzylguanidine. Appl. Radiat. Isot. 44, 621\u2212628","author":"Vaidyanathan G.","year":"1993"},{"key":"bc010032rb00021\/bc010032rb00021_1","first-page":"64","volume":"22","author":"Vaidyanathan G.","year":"1995","journal-title":"Nucl. Med. Biol."},{"key":"bc010032rb00022\/bc010032rb00022_1","doi-asserted-by":"crossref","DOI":"10.1021\/jm00047a022","volume":"37","author":"Vaidyanathan G.","year":"1994","journal-title":"J. Med. Chem."},{"key":"bc010032rb00023\/bc010032rb00023_1","volume":"36","author":"Vaidyanathan G.","year":"1995","journal-title":"J. Nucl. Med."},{"key":"bc010032rb00024\/bc010032rb00024_1","volume":"38","author":"Vaidyanathan G.","year":"1997","journal-title":"J. Nucl. Med."},{"key":"bc010032rb00025\/bc010032rb00025_1","doi-asserted-by":"crossref","DOI":"10.1038\/bjc.1997.366","volume":"76","author":"Vaidyanathan G.","year":"1997","journal-title":"Br. J. Cancer"},{"key":"bc010032rb00026\/bc010032rb00026_1","volume-title":"Iodopyridine-for-iodobenzene substitution for use with low-molecular weight radiopharmaceuticals:\u2009 application to meta-iodobenzylguanidine. Bioconjugate Chem. 9, 758\u2212764","author":"Vaidyanathan G.","year":"1998"},{"key":"bc010032rb00027\/bc010032rb00027_1","volume-title":"Synthesis of ring- and side-chain-substituted m-iodobenzylguanidine analogues. Bioconjugate Chem. 12, 786\u2212797","author":"Vaidyanathan G.","year":"2001"},{"key":"bc010032rb00028\/bc010032rb00028_1","doi-asserted-by":"crossref","DOI":"10.1007\/BF00173043","volume":"21","author":"Wafelman A. R.","year":"1994","journal-title":"Eur. J. Nucl. Med."},{"key":"bc010032rb00029\/bc010032rb00029_1","volume-title":"A comparison of the radiochemical stability of different iodine-131 labeled metaiodobenzylguanidine formulations for therapeutic use. Appl. Radiat. Isot. 45, 183\u2212189","author":"Wafelman A. R.","year":"1994"},{"key":"bc010032rb00030\/bc010032rb00030_1","first-page":"153","volume-title":"Radiopharmaceuticals:\u2009 Progress and Clinical Perspectives","author":"Wieland D. M.","year":"1986"},{"key":"bc010032rb00031\/bc010032rb00031_1","doi-asserted-by":"crossref","DOI":"10.1021\/jm00368a008","volume":"27","author":"Wieland D. M.","year":"1984","journal-title":"J. Med. Chem."},{"key":"bc010032rb00032\/bc010032rb00032_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0021-9258(18)45638-4","volume":"262","author":"Zimmerman T. P.","year":"1987","journal-title":"J. Biol. Chem."},{"key":"bc010032rb00033\/bc010032rb00033_1","volume":"70","author":"Zou J.","year":"1998","journal-title":"J. Inorg. Biochem."},{"key":"bc010032rn00001\/bc010032rn00001_1","unstructured":"Abbreviations:\u2009 ABG, 4-aminobenzylguanidine; CIBG, 4-chloro-3-iodobenzylguanidine; DHIBG, 3,4-dihydroxy-5-iodobenzylguanidine; DMI, desipramine; FIBG, 4-fluoro-3-iodobenzylguanidine; HIBG, 4-hydroxy-3-iodobenzylguanidine; HIMBG, 4-hydroxy-3-iodo-5-methoxybenzylguanidine;mAIBG, 5-amino-3-iodobenzylguanidine; MIBG,m-iodobenzylguanidine;mINBG, 5-iodo-3-nitrobenzylguanidine; nca, no-carrier-added; NET, norepinephrine transporter; NHIBG,N1-hydroxy-N3-3-iodobenzylguanidine;pAIBG, 4-amino-3-iodobenzylguanidine;pINBG, 3-iodo-4-nitrobenzylguanidine."}],"container-title":["Bioconjugate Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bc010032r","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T08:24:54Z","timestamp":1679559894000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bc010032r"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,8,18]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,9,1]]}},"alternative-id":["10.1021\/bc010032r"],"URL":"https:\/\/doi.org\/10.1021\/bc010032r","relation":{},"ISSN":["1043-1802","1520-4812"],"issn-type":[{"value":"1043-1802","type":"print"},{"value":"1520-4812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,8,18]]}}}