{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T09:08:56Z","timestamp":1761988136992},"reference-count":49,"publisher":"American Chemical Society (ACS)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioconjugate Chem."],"published-print":{"date-parts":[[2007,7,1]]},"DOI":"10.1021\/bc060392k","type":"journal-article","created":{"date-parts":[[2007,5,18]],"date-time":"2007-05-18T23:59:22Z","timestamp":1179532762000},"page":"1123-1130","source":"Crossref","is-referenced-by-count":15,"title":["Synthesis and Testing of a Binary Catalytic System for Imaging of Signal Amplification <i>in Vivo<\/i>"],"prefix":"10.1021","volume":"18","author":[{"given":"Alexei","family":"Bogdanov,","sequence":"first","affiliation":[{"name":"Department of Radiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye-Won","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Querol","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Hendrik","family":"Pretorius","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Yudina","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2007,5,18]]},"reference":[{"key":"bc060392kb00001\/bc060392kb00001_1","unstructured":"Torchilin, V. (1995)Targeted delivery of imaging agentsp 732, CRC Press, Boca Raton, FL."},{"key":"bc060392kb00002\/bc060392kb00002_1","doi-asserted-by":"crossref","DOI":"10.3322\/canjclin.56.4.226","volume":"56","author":"Sharkey R. M.","year":"2006","journal-title":"CA Cancer J. Clin."},{"key":"bc060392kb00003\/bc060392kb00003_1","volume-title":"Engineering antibodies for imaging and therapy. Curr. Opin. Biotechnol. 8, 449\u221254","author":"Carter P.","year":"1997"},{"key":"bc060392kb00004\/bc060392kb00004_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0022-1759(99)00161-1","volume":"231","author":"Adams G. P.","year":"1999","journal-title":"J. Immunol. Methods"},{"key":"bc060392kb00005\/bc060392kb00005_1","volume-title":"Minibody:\u2009 A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain fv-ch3) which exhibits rapid, high-level targeting of xenografts. Cancer Res. 56, 3055\u221261","author":"Hu S.","year":"1996"},{"key":"bc060392kb00006\/bc060392kb00006_1","volume":"43","author":"Ladner R. C.","year":"1999","journal-title":"Q. J. Nucl. Med."},{"key":"bc060392kb00007\/bc060392kb00007_1","volume-title":"Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis. Circulation 114, 1504\u221211","author":"Nahrendorf M.","year":"2006"},{"key":"bc060392kb00008\/bc060392kb00008_1","volume-title":"Identification and characterization of nuclease-stabilized rna molecules that bind human prostate cancer cells via the prostate-specific membrane antigen. Cancer Res. 62, 4029\u221233","author":"Lupold S. E.","year":"2002"},{"key":"bc060392kb00009\/bc060392kb00009_1","volume-title":"Targeted inhibition of alphavbeta3 integrin with an rna aptamer impairs endothelial cell growth and survival. Biochem. Biophys. Res. Commun. 338, 956\u221263","author":"Mi J.","year":"2005"},{"key":"bc060392kb00010\/bc060392kb00010_1","first-page":"35","volume":"16","author":"Williams L. E.","year":"2001","journal-title":"Cancer Biother. Radiopharm."},{"key":"bc060392kb00011\/bc060392kb00011_1","doi-asserted-by":"crossref","unstructured":"Kang, H. W., Josephson, L., Petrovsky, A., Weissleder, R., and Bogdanov, A., Jr. (2002) Magnetic resonance imaging of inducible e-selectin expression in human endothelial cell culture.Bioconjugate Chem.13, 122\u22127.","DOI":"10.1021\/bc0155521"},{"key":"bc060392kb00012\/bc060392kb00012_1","volume-title":"vivo imaging of activated endothelium using an anti-vcam-1 magnetooptical probe. Bioconjugate Chem. 16, 576\u221281","author":"Tsourkas A.","year":"2005"},{"key":"bc060392kb00013\/bc060392kb00013_1","volume":"44","author":"Britz-Cunningham S. H.","year":"2003","journal-title":"J. Nucl. Med."},{"key":"bc060392kb00014\/bc060392kb00014_1","doi-asserted-by":"crossref","unstructured":"Olafsen, T., Kenanova, V. E., Sundaresan, G., Anderson, A. L., Crow, D., Yazaki, P. J., Li, L., Press, M. F., Gambhir, S. S., Williams, L. E., Wong, J. Y., Raubitschek, A. A., Shively, J. E., and Wu, A. M. (2005) Optimizing radiolabeled engineered anti-p185her2 antibody fragments for in vivo imaging.Cancer Res.65, 5907\u221216.","DOI":"10.1158\/0008-5472.CAN-04-4472"},{"key":"bc060392kb00015\/bc060392kb00015_1","volume-title":"Tumor labeling in vivo using cyanine-conjugated monoclonal antibodies. Cancer Immunol. Immunother. 41, 257\u221263","author":"Ballou B.","year":"1995"},{"key":"bc060392kb00016\/bc060392kb00016_1","volume-title":"Monoclonal antibody modification with chelate-linked high-molecular-weight polymers:\u2009 Major increases in polyvalent cation binding without loss of antigen binding. Hybridoma 6, 229\u2212240","author":"Torchilin V.","year":"1987"},{"key":"bc060392kb00017\/bc060392kb00017_1","volume-title":"Targeting of mpeg-protected polyamino acid carrier to human e-selectin in vitro. Amino Acids 23, 301\u2212308","author":"Kang H.","year":"2002"},{"key":"bc060392kb00018\/bc060392kb00018_1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1080\/08982100500528784","volume":"16","author":"Erdogan S.","year":"2006","journal-title":"J. Liposome Res."},{"key":"bc060392kb00019\/bc060392kb00019_1","doi-asserted-by":"crossref","first-page":"7109s","DOI":"10.1158\/1078-0432.CCR-1004-0009","volume":"11","author":"Sharkey R. M.","year":"2005","journal-title":"Clin. Cancer Res."},{"key":"bc060392kb00020\/bc060392kb00020_1","volume-title":"Development of antibodies for cancer therapy. Expert Opin. Biol. Ther. 6, 787\u221296","author":"Wilkins D. K.","year":"2006"},{"key":"bc060392kb00021\/bc060392kb00021_1","volume":"66","author":"Meredith R. F.","year":"2006","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"bc060392kb00022\/bc060392kb00022_1","volume-title":"Des. Select. 19, 359\u221267.","author":"Xiong C. Y.","year":"2006"},{"key":"bc060392kb00023\/bc060392kb00023_1","volume":"33","author":"Rusckowski M.","year":"1992","journal-title":"J. Nucl. Med."},{"key":"bc060392kb00024\/bc060392kb00024_1","doi-asserted-by":"crossref","unstructured":"van Schaijk, F. G., Oosterwijk, E., Soede, A. C., Broekema, M., Frielink, C., McBride, W. J., Goldenberg, D. M., Corstens, F. H., and Boerman, O. C. (2005) Pretargeting of carcinoembryonic antigen-expressing tumors with a biologically produced bispecific anticarcinoembryonic antigen x anti-indium-labeled diethylenetriaminepentaacetic acid antibody.Clin. Cancer Res. 11, 7130s\u22127136s.","DOI":"10.1158\/1078-0432.CCR-1004-0006"},{"key":"bc060392kb00025\/bc060392kb00025_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinorgbio.2006.01.004","volume":"100","author":"Corneillie T. M.","year":"2006","journal-title":"J. Inorg. Biochem."},{"key":"bc060392kb00026\/bc060392kb00026_1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1021\/bc00019a013","volume":"4","author":"Kuijpers W. H.","year":"1993","journal-title":"Bioconjugate Chem."},{"key":"bc060392kb00027\/bc060392kb00027_1","volume":"45","author":"He J.","year":"2004","journal-title":"J. Nuclear Med."},{"key":"bc060392kb00028\/bc060392kb00028_1","volume":"34","author":"del Rosario R. B.","year":"1993","journal-title":"J. Nuclear Med."},{"key":"bc060392kb00029\/bc060392kb00029_1","volume-title":"Magnetic resonance molecular imaging of the her-2\/neu receptor. Cancer Res. 63, 2723\u22127","author":"Artemov D.","year":"2003"},{"key":"bc060392kb00030\/bc060392kb00030_1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1162\/15353500200200001","volume":"1","author":"Bogdanov A. J.","year":"2002","journal-title":"Mol. Imaging"},{"key":"bc060392kb00031\/bc060392kb00031_1","volume":"14","author":"Bogdanov A. J.","year":"2006","journal-title":"Intl. Soc. Mag. Reson. Med."},{"key":"bc060392kb00032\/bc060392kb00032_1","doi-asserted-by":"crossref","DOI":"10.1021\/ol050208v","volume":"7","author":"Querol M.","year":"2005","journal-title":"Org. Lett."},{"key":"bc060392kb00033\/bc060392kb00033_1","volume-title":"A paramagnetic contrast agent with myeloperoxidase-sensing properties. Org. Biomol. Chem. 4","author":"Querol M.","year":"2006"},{"key":"bc060392kb00034\/bc060392kb00034_1","volume-title":"Immunother. 46, 167\u221273.","author":"Bier H.","year":"1998"},{"key":"bc060392kb00035\/bc060392kb00035_1","volume-title":"Binding of an antagonistic monoclonal antibody to an intact and fragmented EGF-receptor polypeptide. Arch. Biochem. Biophys. 252, 549\u221260","author":"Murthy U.","year":"1987"},{"key":"bc060392kb00036\/bc060392kb00036_1","volume-title":"Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor:\u2009 Immunologically mediated and effector cell-independent effects. Cancer Res. 47, 3692\u22126","author":"Rodeck U.","year":"1987"},{"key":"bc060392kb00037\/bc060392kb00037_1","first-page":"23","volume":"1","author":"Bogdanov A., Jr.","year":"2002","journal-title":"Mol Imaging"},{"key":"bc060392kb00038\/bc060392kb00038_1","volume-title":"Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates. Radiology 240, 473\u221281","author":"Chen J. W.","year":"2006"},{"key":"bc060392kb00039\/bc060392kb00039_1","volume-title":"Myeloperoxidase activity imaging using Ga-67 labeled substrate. Mol. Imaging Biol. 7, 403\u221210","author":"Querol Sans M.","year":"2005"},{"key":"bc060392kb00040\/bc060392kb00040_1","volume-title":"Metabolic biotinylation of cell surface receptors for in vivo imaging. Nat. Methods 3, 291\u2212396","author":"Tannous B.","year":"2006"},{"key":"bc060392kb00041\/bc060392kb00041_1","doi-asserted-by":"crossref","DOI":"10.1038\/sj.bjc.6603083","volume":"94","author":"Graeven U.","year":"2006","journal-title":"Br. J. Cancer"},{"key":"bc060392kb00042\/bc060392kb00042_1","volume-title":"Epidermal growth factor receptor inhibitors:\u2009 A new prospective in the treatment of lung cancer. Curr. Med. Chem. Anti-Cancer Agents 4, 139\u221248","author":"Tiseo M.","year":"2004"},{"key":"bc060392kb00043\/bc060392kb00043_1","doi-asserted-by":"crossref","unstructured":"Bier, H., Hoffmann, T., Hauser, U., Wink, M., Ochler, M., Kovar, A., Muser, M., and Knecht, R. (2001) Clinical trial with escalating doses of the antiepidermal growth factor receptor humanized monoclonal antibody EMD 72000 in patients with advanced squamous cell carcinoma of the larynx and hypopharynx.Cancer Chemother. Pharmacol.47, 519\u221224.","DOI":"10.1007\/s002800000270"},{"key":"bc060392kb00044\/bc060392kb00044_1","volume-title":"vivo near-infrared fluorescence imaging. Curr. Opin. Chem. Biol. 7, 626\u221234","author":"Frangioni J. V.","year":"2003"},{"key":"bc060392kb00045\/bc060392kb00045_1","doi-asserted-by":"crossref","DOI":"10.1152\/ajplung.2000.278.4.L794","volume":"278","author":"Christofidou-Solomidou M.","year":"2000","journal-title":"Amer. J. Physiol., Lung Cell Mol. Physiol."},{"key":"bc060392kb00046\/bc060392kb00046_1","volume":"266","author":"Samoszuk M.","year":"1993","journal-title":"J. Pharm. Exp. Ther."},{"key":"bc060392kb00047\/bc060392kb00047_1","volume-title":"Specific killing of human endothelial cells by antibody-conjugated glucose oxidase. Anal. Biochem. 169, 383\u22129","author":"Muzykantov V. R.","year":"1988"},{"key":"bc060392kb00048\/bc060392kb00048_1","first-page":"90","volume":"56","author":"Samoszuk M. K.","year":"1996","journal-title":"Cancer Res."},{"key":"bc060392kn00001\/bc060392kn00001_1","volume-title":"Dulbecco's phosphate-buffered saline","author":"Abbreviations DPBS"}],"container-title":["Bioconjugate Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bc060392k","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T05:43:28Z","timestamp":1632462208000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bc060392k"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,18]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,7,1]]}},"alternative-id":["10.1021\/bc060392k"],"URL":"https:\/\/doi.org\/10.1021\/bc060392k","relation":{},"ISSN":["1043-1802","1520-4812"],"issn-type":[{"value":"1043-1802","type":"print"},{"value":"1520-4812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,18]]}}}