{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T08:45:35Z","timestamp":1769417135253,"version":"3.49.0"},"reference-count":64,"publisher":"American Chemical Society (ACS)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioconjugate Chem."],"published-print":{"date-parts":[[2012,12,19]]},"DOI":"10.1021\/bc3004342","type":"journal-article","created":{"date-parts":[[2012,11,29]],"date-time":"2012-11-29T08:43:26Z","timestamp":1354178606000},"page":"2403-2416","source":"Crossref","is-referenced-by-count":23,"title":["Design, Synthesis, and X-ray Analysis of a Glycoconjugate Bound to Mycobacterium tuberculosis Antigen 85C"],"prefix":"10.1021","volume":"23","author":[{"given":"Diaa A.","family":"Ibrahim","sequence":"first","affiliation":[{"name":"National Organization for Drug Control & Research, Cairo, Gizaa, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Boucau","sequence":"additional","affiliation":[{"name":"Department of Chemistry, The University of Toledo, 2801 W. Bancroft Street,\rToledo, Ohio 43606, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel H.","family":"Lajiness","sequence":"additional","affiliation":[{"name":"Department of Chemistry, The University of Toledo, 2801 W. Bancroft Street,\rToledo, Ohio 43606, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sri Kumar","family":"Veleti","sequence":"additional","affiliation":[{"name":"Department of Chemistry, The University of Toledo, 2801 W. Bancroft Street,\rToledo, Ohio 43606, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin R.","family":"Trabbic","sequence":"additional","affiliation":[{"name":"Department of Chemistry, The University of Toledo, 2801 W. Bancroft Street,\rToledo, Ohio 43606, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel S.","family":"Adams","sequence":"additional","affiliation":[{"name":"Department of Chemistry, The University of Toledo, 2801 W. Bancroft Street,\rToledo, Ohio 43606, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald R.","family":"Ronning","sequence":"additional","affiliation":[{"name":"Department of Chemistry, The University of Toledo, 2801 W. Bancroft Street,\rToledo, Ohio 43606, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven J.","family":"Sucheck","sequence":"additional","affiliation":[{"name":"Department of Chemistry, The University of Toledo, 2801 W. Bancroft Street,\rToledo, Ohio 43606, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2012,12,10]]},"reference":[{"key":"ref1\/cit1","volume-title":"Addressing the Threat of Drug-Resistant Tuberculosis: A Realistic Assessment of the Challenge. Workshop Summary","author":"Institute of Medicine of the National Academies","year":"2009"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.2174\/1389450024605391","volume":"3","author":"Zhang Y.","year":"2002","journal-title":"Curr. Drug Targets"},{"key":"ref3\/cit3","first-page":"147","volume-title":"Microbial Glycobiology","author":"Chatterjee D.","year":"2009"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1146\/annurev.bi.64.070195.000333","volume":"64","author":"Brennan P. J.","year":"1995","journal-title":"Annu. Rev. Biochem."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"11919","DOI":"10.1073\/pnas.93.21.11919","volume":"93","author":"Belanger A. E.","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/nm0597-567","volume":"3","author":"Telenti A.","year":"1997","journal-title":"Nat. Med."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1128\/AAC.2.1.29","volume":"2","author":"Takayama K.","year":"1972","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"197","DOI":"10.2174\/1389201023378328","volume":"3","author":"Schroeder E. K.","year":"2002","journal-title":"Curr. Pharm. Biotechnol."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1128\/CMR.18.1.81-101.2005","volume":"18","author":"Takayama K.","year":"2005","journal-title":"Clin. Microbiol. Rev."},{"key":"ref10\/cit10","first-page":"189","volume":"8","author":"Fukui Y.","year":"1965","journal-title":"Biken J."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/0006-291X(82)91841-1","volume":"108","author":"Kilburn J. O.","year":"1982","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"13417","DOI":"10.1016\/S0021-9258(19)76442-4","volume":"262","author":"Sathyamoorthy N.","year":"1987","journal-title":"J. Biol. Chem."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1046\/j.1365-2958.1999.01310.x","volume":"31","author":"Jackson M.","year":"1999","journal-title":"Mol. Microbiol."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1046\/j.1365-2958.2000.01738.x","volume":"35","author":"Puech V.","year":"2000","journal-title":"Mol. Microbiol."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1126\/science.276.5317.1420","volume":"276","author":"Belisle J. T.","year":"1997","journal-title":"Science"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"15614","DOI":"10.1073\/pnas.242612299","volume":"99","author":"Harth G.","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"7199","DOI":"10.1073\/pnas.0701725104","volume":"104","author":"Harth G.","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1146\/annurev-pharmtox-061008-103123","volume":"49","author":"Nguyen L.","year":"2009","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ejmech.2006.08.007","volume":"42","author":"Gobec S.","year":"2007","journal-title":"Eur. J. Med. Chem."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1046\/j.1472-765x.2002.01091.x","volume":"34","author":"Kremer L.","year":"2002","journal-title":"Lett. Appl. Microbiol."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"6397","DOI":"10.1016\/j.bmc.2004.09.033","volume":"12","author":"Wang J.","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0008-6215(01)00288-9","volume":"337","author":"Rose J. D.","year":"2002","journal-title":"Carbohydr. Res."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"13232","DOI":"10.1021\/ja204249p","volume":"133","author":"Barry C. S.","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0008-6215(00)85758-4","volume":"69","author":"Kam B. L.","year":"1979","journal-title":"Carbohydr. Res."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0960-894X(98)00049-3","volume":"8","author":"Ayers J. D.","year":"1998","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"5672","DOI":"10.1016\/j.bmc.2008.03.062","volume":"16","author":"Sanki A. K.","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.ab.2008.10.018","volume":"385","author":"Boucau J.","year":"2009","journal-title":"Anal. Biochem."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1039\/b902284h","volume":"5","author":"Sanki A. K.","year":"2009","journal-title":"Mol. BioSyst."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"36771","DOI":"10.1074\/jbc.M400811200","volume":"279","author":"Ronning D. R.","year":"2004","journal-title":"J. Biol. Chem."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1006\/jmbi.2001.4461","volume":"307","author":"Anderson D. H.","year":"2001","journal-title":"J. Mol. Biol."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0301-4622(03)00101-7","volume":"105","author":"Goulding C. W.","year":"2003","journal-title":"Biophys. Chem."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/72458","volume":"7","author":"Tonge P. J.","year":"2000","journal-title":"Nat. Struct. Biol."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/72413","volume":"7","author":"Ronning D. R.","year":"2000","journal-title":"Nat. Struct. Biol."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/s10719-008-9211-z","volume":"5","author":"Sanki A. K.","year":"2009","journal-title":"Glycoconj. J."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1002\/med.20190","volume":"30","author":"Umesiri F. E.","year":"2010","journal-title":"Med. Res. Rev."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1021\/jm00126a020","volume":"32","author":"Amemiya Y.","year":"1989","journal-title":"J. Med. Chem."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"13757","DOI":"10.1016\/S0040-4020(99)00859-5","volume":"55","author":"Bilokin Y. V.","year":"1999","journal-title":"Tetrahedron"},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1021\/jm0210212","volume":"46","author":"Baraldi P. G.","year":"2003","journal-title":"J. Med. Chem."},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"4002","DOI":"10.1016\/j.bmcl.2006.05.011","volume":"16","author":"Bishop A. C.","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1021\/jm060631p","volume":"50","author":"Kaila N.","year":"2007","journal-title":"J. Med. Chem."},{"key":"ref41\/cit41","unstructured":"Sanki, A. K., Sucheck, S. J., Ronning, D. R., Boucau, J., Umesiri, F. E., and Ibrahim, D. A. (2010) Inhibitors of Antigen 85 from Mycobacterium tuberculosis,Abstracts of Papers, 239th ACS National Meeting,March 21\u201325,San Francisco, CA, United States, ORGN-118."},{"key":"ref42\/cit42","unstructured":"Ibrahim, D. A., Adams, S. S., Sucheck, S. J., Trabbic, K. R., Ronning, D. R., Sanki, A. K., and Boucau, J. (2010) Inhibitors ofMycobacterium tuberculosisAntigen 85,Abstracts, 41st Central Regional Meeting of the ACS,June 16\u201319,Dayton, OH, United States, CERMACS-307."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"8362","DOI":"10.1021\/jm100993z","volume":"53","author":"Scheich C.","year":"2010","journal-title":"J. Med. Chem."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1128\/AAC.05742-11","volume":"56","author":"Warrier T.","year":"2012","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0076-6879(97)76066-X","volume":"276","author":"Otwinowski Z.","year":"1997","journal-title":"Methods Enzymol."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1107\/S0907444998012517","volume":"55","author":"Kissinger C. R.","year":"1999","journal-title":"Acta Crystallogr., Sect. D: Biol. Crystallogr."},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1107\/S0907444910007493","volume":"66","author":"Emsley P.","year":"2010","journal-title":"Acta Crystallogr., Sect. D: Biol. Crystallogr."},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1107\/S0909049503024130","volume":"11","author":"Adams P. D.","year":"2004","journal-title":"J. Synchrotron Radiat."},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1107\/S0907444902016657","volume":"58","author":"Adams P. D.","year":"2002","journal-title":"Acta Crystallogr., Sect. D: Biol. Crystallogr."},{"key":"ref50\/cit50","unstructured":"National Committee for Clinical Laboratory Standards (2000) Approved Standard: M2-A7,Performance standards for antimicrobial disk susceptibility tests,7th ed.National Committee for Clinical Laboratory Standards,Wayne, PA."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/jhet.5570230126","volume":"23","author":"Peet N. P.","year":"1986","journal-title":"J. Heterocycl. Chem."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/cber.19660990116","volume":"99","author":"Gewald K.","year":"1966","journal-title":"Chem. Ber."},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1080\/14756360500480418","volume":"21","author":"Khan K. M.","year":"2006","journal-title":"J. Enzym. Inhib. Med. Chem."},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/jhet.5570130425","volume":"13","author":"Manhas M. S.","year":"1976","journal-title":"Heterocycl. Chem."},{"key":"ref55\/cit55","unstructured":"Hagen, H., Nilz, G., Walter, H., and Landes, A. (1995) Preparation of 2-aminothiophene derivatives as herbicide antidotes. U. S. Patent 5,442,335, June 6, 1995."},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1248\/cpb.37.2091","volume":"37","author":"Sugiyama M.","year":"1989","journal-title":"Chem. Pharm. Bull."},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.tetlet.2005.11.049","volume":"47","author":"Yoshimura Y.","year":"2006","journal-title":"Tetrahedron Lett."},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0008-6215(94)80043-X","volume":"257","author":"Hughes N. A.","year":"1994","journal-title":"Carbohydr. Res."},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"11729","DOI":"10.1021\/jm0306430","volume":"47","author":"Friesner R. A.","year":"2004","journal-title":"J. Med. Chem."},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/prot.10613","volume":"55","author":"Jacobson M. P.","year":"2004","journal-title":"Proteins"},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"6474","DOI":"10.1021\/jp003919d","volume":"105","author":"Kaminski G. A.","year":"2001","journal-title":"Phys. Chem. B"},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/jcc.20307","volume":"27","author":"Yu Z.","year":"2006","journal-title":"J. Comput. Chem."},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1021\/jo981576y","volume":"64","author":"Garc\u00eda-l\u00f3pez J.","year":"1999","journal-title":"J. Org. Chem."},{"key":"ref64\/cit64","first-page":"1721","volume":"12","author":"Skaanderup P. R.","year":"2002","journal-title":"Synthesis"}],"container-title":["Bioconjugate Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bc3004342","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T21:32:11Z","timestamp":1682285531000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bc3004342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,10]]},"references-count":64,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12,19]]}},"alternative-id":["10.1021\/bc3004342"],"URL":"https:\/\/doi.org\/10.1021\/bc3004342","relation":{},"ISSN":["1043-1802","1520-4812"],"issn-type":[{"value":"1043-1802","type":"print"},{"value":"1520-4812","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,10]]}}}