{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T13:10:11Z","timestamp":1680786611802},"reference-count":38,"publisher":"American Chemical Society (ACS)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Bioconjugate Chem."],"published-print":{"date-parts":[[1996,1,1]]},"DOI":"10.1021\/bc960010i","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T05:13:40Z","timestamp":1027660420000},"page":"290-297","source":"Crossref","is-referenced-by-count":4,"title":["Thiolations, <sup>99m<\/sup>Tc Labelings, and Animal <i>In Vivo<\/i> Biodistributions of Divalent Monoclonal Antibody Fragments"],"prefix":"10.1021","volume":"7","author":[{"given":"Serengulam V.","family":"Govindan","sequence":"first","affiliation":[{"name":"Immunomedics, Inc., Morris Plains, New Jersey 07950, and Garden State Cancer Center at the Center for Molecular Medicine and Immunology, Newark, New Jersey 07103"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M.","family":"Goldenberg","sequence":"additional","affiliation":[{"name":"Immunomedics, Inc., Morris Plains, New Jersey 07950, and Garden State Cancer Center at the Center for Molecular Medicine and Immunology, Newark, New Jersey 07103"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth C.","family":"Grebenau","sequence":"additional","affiliation":[{"name":"Immunomedics, Inc., Morris Plains, New Jersey 07950, and Garden State Cancer Center at the Center for Molecular Medicine and Immunology, Newark, New Jersey 07103"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans J.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Immunomedics, Inc., Morris Plains, New Jersey 07950, and Garden State Cancer Center at the Center for Molecular Medicine and Immunology, Newark, New Jersey 07103"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary L.","family":"Griffiths","sequence":"additional","affiliation":[{"name":"Immunomedics, Inc., Morris Plains, New Jersey 07950, and Garden State Cancer Center at the Center for Molecular Medicine and Immunology, Newark, New Jersey 07103"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[1996,5,28]]},"reference":[{"key":"bc960010ib00001\/bc960010ib00001_1","doi-asserted-by":"crossref","DOI":"10.1016\/0002-9343(93)90062-T","volume":"94","author":"Goldenberg D. M.","year":"1993","journal-title":"Am. J. Med."},{"key":"bc960010ib00002\/bc960010ib00002_1","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/S0001-2998(05)80089-3","volume":"23","author":"Serafini A. N.","year":"1993","journal-title":"Semin. Nucl. Med."},{"key":"bc960010ib00003\/bc960010ib00003_1","doi-asserted-by":"crossref","DOI":"10.1001\/jama.1989.03420050094047","volume":"261","author":"Schlom J.","year":"1989","journal-title":"J. Am. Med Assoc."},{"key":"bc960010ib00004\/bc960010ib00004_1","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1021\/bc00014a001","volume":"3","author":"Griffiths G. L.","year":"1992","journal-title":"Bioconjugate Chem."},{"key":"bc960010ib00005\/bc960010ib00005_1","first-page":"70","volume":"34","author":"Goldenberg D. M.","year":"1993","journal-title":"J. Nucl. Med."},{"key":"bc960010ib00006\/bc960010ib00006_1","volume-title":"Pre-clinical studies of an \u201cinstant","author":"Hansen H. J.","year":"1990"},{"key":"bc960010ib00007\/bc960010ib00007_1","volume":"36","author":"Behr T. M.","year":"1995","journal-title":"J. Nucl. Med."},{"key":"bc960010ib00008\/bc960010ib00008_1","doi-asserted-by":"crossref","DOI":"10.1007\/BF00177366","volume":"19","author":"Fjeld J. G.","year":"1992","journal-title":"Eur. J. Nucl. Med."},{"key":"bc960010ib00009\/bc960010ib00009_1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0065-2776(08)60574-X","volume":"35","author":"Spiegelberg H. L.","year":"1984","journal-title":"Adv. Immunol."},{"key":"bc960010ib00010\/bc960010ib00010_1","volume-title":"Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen. Cancer 71, 3478\u22123485","author":"Hansen H. J.","year":"1993"},{"key":"bc960010ib00011\/bc960010ib00011_1","volume-title":"Thiol-containing cross-linking agent with enhanced steric hindrance. Bioconjugate Chem. 1, 400\u2212410","author":"Greenfield L.","year":"1990"},{"key":"bc960010ib00012\/bc960010ib00012_1","volume-title":"A centrifuged-column procedure for the measurement of ligand binding by beef heart F1. Methods Enzymol. 56, 527\u2212530","author":"Penefsky H. S.","year":"1979"},{"key":"bc960010ib00013\/bc960010ib00013_1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0003-9861(59)90090-6","volume":"82","author":"Ellman G. L.","year":"1959","journal-title":"Arch. Biochem. Biophys."},{"key":"bc960010ib00014\/bc960010ib00014_1","volume-title":"Vitro (Rockville) 12, 180\u2212191.","author":"Tom B. H.","year":"1976"},{"key":"bc960010ib00015\/bc960010ib00015_1","first-page":"217P","volume":"34","author":"Shevitz J.","year":"1993","journal-title":"J. Nucl. Med."},{"key":"bc960010ib00016\/bc960010ib00016_1","volume-title":"Monoclonal antibodies to colon-specific antigen-p (Csap). Cancer Res. 50, 6405\u22126409","author":"Gold D. V.","year":"1990"},{"key":"bc960010ib00017\/bc960010ib00017_1","volume-title":"Murine monoclonal antibodies raised against human non-small cell carcinoma of the lung:\u2009 specificity and tumor targeting. Cancer Res. 50, 1330\u22121336","author":"Stein R.","year":"1990"},{"key":"bc960010ib00018\/bc960010ib00018_1","volume-title":"EPB-1 and EPB-2, reactive with human lymphoma. Cancer Res. 49, 4568\u22124577.","author":"Pawlak-Byczkowska E. J.","year":"1989"},{"key":"bc960010ib00019\/bc960010ib00019_1","volume-title":"The use of monoclonal antibodies and antibody fragments in the imaging of infectious lesions. Semin. Nucl. Med. 24, 142\u2212153","author":"Becker W.","year":"1994"},{"key":"bc960010ib00020\/bc960010ib00020_1","volume-title":"The chemical modification of biopolymers III. The introduction of SH groups into Taka-amylase A. Bull. Chem. Soc. Jpn. 43, 3849\u22123852","author":"Suzuki S.","year":"1970"},{"key":"bc960010ib00021\/bc960010ib00021_1","volume-title":"Proc. Natl. Acad. Sci. U.S.A. 85","author":"Fritzberg A. R.","year":"1988"},{"key":"bc960010ib00022\/bc960010ib00022_1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/0969-8051(94)90125-2","volume":"21","author":"Tibben J. G.","year":"1994","journal-title":"Nucl. Med. Biol."},{"key":"bc960010ib00023\/bc960010ib00023_1","first-page":"29P","volume":"35","author":"Abrams M. J.","year":"1994","journal-title":"J. Nucl. Med."},{"key":"bc960010ib00024\/bc960010ib00024_1","first-page":"28","volume":"177","author":"Brown B. A.","year":"1988","journal-title":"Anal. Biochem."},{"key":"bc960010ib00025\/bc960010ib00025_1","volume-title":"The stability of 99mTc directly labeled to an Fab\u2018 antibody via stannous ion and mercaptoethanol reduction. Nucl. Med. Commun. 13, 503\u2212512","author":"Mardirossian G.","year":"1992"},{"key":"bc960010ib00026\/bc960010ib00026_1","volume":"27","author":"Rhodes B. A.","year":"1986","journal-title":"J. Nucl. Med."},{"key":"bc960010ib00027\/bc960010ib00027_1","volume-title":"Evaluation of a direct method for technetium labeling intact and F(ab\u2018)2 1A3, an anticolorectal monoclonal antibody. Nucl. Med. Biol. 21, 619\u2212626","author":"Schwarz S. W.","year":"1994"},{"key":"bc960010ib00028\/bc960010ib00028_1","volume-title":"Preparation of a pure 99mTc\u2212F(ab\u2018)2 radioimmunoconjugate by direct labeling methods. Nucl. Med. Biol. 21, 649\u2212655","author":"Griffiths G. L.","year":"1994"},{"key":"bc960010ib00029\/bc960010ib00029_1","volume-title":"Simplified method for conjugating macrocyclic bifunctional chelating agents to antibodies via 2-iminothiolane. Bioconjugate Chem. 1, 222\u2212226","author":"McCall M. J.","year":"1990"},{"key":"bc960010ib00030\/bc960010ib00030_1","volume-title":"[99mTc]Tricine:\u2009 A useful precursor complex for the radiolabeling of hydrazinonicotinate protein conjugates. Bioconjugate Chem. 6, 635\u2212638","author":"Larsen S. K.","year":"1995"},{"key":"bc960010ib00031\/bc960010ib00031_1","volume-title":"Can a cysteine challenge assay predict the in vivo behavior of 99mTc-labeled antibodies? Nucl. Med. Biol. 21, 1035\u22121044","author":"Hnatowich D. J.","year":"1994"},{"key":"bc960010ib00032\/bc960010ib00032_1","volume-title":"Labeling small quantities of monoclonal antibodies and their F(ab\u2018)2 fragments with technetium-99m. Nucl. Med. Biol. 22, 451\u2212457","author":"Tesic M.","year":"1995"},{"key":"bc960010ib00033\/bc960010ib00033_1","first-page":"7","volume":"18","author":"Eckelman W. C.","year":"1991","journal-title":"Nucl. Med. Biol."},{"key":"bc960010ib00034\/bc960010ib00034_1","doi-asserted-by":"crossref","DOI":"10.1007\/BF00998164","volume":"16","author":"Buscombe J. R.","year":"1990","journal-title":"Eur. J. Nucl. Med."},{"key":"bc960010ib00035\/bc960010ib00035_1","volume":"34","author":"Hnatowich D. J.","year":"1993","journal-title":"J. Nucl. Med."},{"key":"bc960010ib00036\/bc960010ib00036_1","volume":"33","author":"Fritzberg A. R.","year":"1992","journal-title":"J. Nucl. Med."},{"key":"bc960010ib00037\/bc960010ib00037_1","volume":"34","author":"Griffiths G. L.","year":"1993","journal-title":"J. Nucl. Med."},{"key":"bc960010in00001\/bc960010in00001_1","volume-title":"acetate-buffered 150 mM sodium chloride (pH 5.3)","author":"Abbreviations ABS"}],"container-title":["Bioconjugate Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bc960010i","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,6]],"date-time":"2023-04-06T12:54:54Z","timestamp":1680785694000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bc960010i"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1,1]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1996,1,1]]}},"alternative-id":["10.1021\/bc960010i"],"URL":"https:\/\/doi.org\/10.1021\/bc960010i","relation":{},"ISSN":["1043-1802","1520-4812"],"issn-type":[{"value":"1043-1802","type":"print"},{"value":"1520-4812","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1,1]]}}}