{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T19:15:50Z","timestamp":1790968550093,"version":"4.1.0"},"reference-count":59,"publisher":"American Chemical Society (ACS)","issue":"25","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2000,6,1]]},"DOI":"10.1021\/bi000101+","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T05:51:53Z","timestamp":1027662713000},"page":"7580-7588","source":"Crossref","is-referenced-by-count":30,"title":["Inhibition of Carboxypeptidase A by <scp>d<\/scp>-Penicillamine:\u2009 Mechanism and Implications for Drug Design"],"prefix":"10.1021","volume":"39","author":[{"given":"Curtis R.","family":"Chong","sequence":"first","affiliation":[{"name":"Center for Biochemical and Biophysical Sciences and Medicine and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Auld","sequence":"additional","affiliation":[{"name":"Center for Biochemical and Biophysical Sciences and Medicine and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2000,5,31]]},"reference":[{"key":"bi0001011b00001\/bi0001011b00001_1","volume-title":"Science 196, 441\u22124","author":"Ondetti M. A.","year":"1977"},{"key":"bi0001011b00002\/bi0001011b00002_1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0163-7258(97)00023-5","volume":"75","author":"Rasmussen H. S.","year":"1997","journal-title":"Pharmacol. Ther."},{"key":"bi0001011b00003\/bi0001011b00003_1","volume-title":"Baillieres Clin. Rheumatol. 4, 553\u221274","author":"Joyce D. A.","year":"1990"},{"key":"bi0001011b00004\/bi0001011b00004_1","volume-title":"Lancet 338, 1565\u22128","author":"Kean W. F.","year":"1991"},{"key":"bi0001011b00005\/bi0001011b00005_1","volume-title":"Mol. Pharmacol. 5, 200\u22129","author":"Peisach J.","year":"1969"},{"key":"bi0001011b00006\/bi0001011b00006_1","doi-asserted-by":"crossref","DOI":"10.1093\/rheumatology\/36.1.104","volume":"36","author":"Munro R.","year":"1997","journal-title":"Br. J. Rheumatol."},{"key":"bi0001011b00007\/bi0001011b00007_1","volume-title":"Curr. Opin. Rheumatol. 8, 176\u221282","author":"Conaghan P. G.","year":"1996"},{"key":"bi0001011b00008\/bi0001011b00008_1","volume":"11","author":"Chong C. R.","year":"1998","journal-title":"J. Trace Elem. Exp. Med."},{"key":"bi0001011b00009\/bi0001011b00009_1","volume-title":"Biochemistry 18, 4362\u22126","author":"Bazzone T. J.","year":"1979"},{"key":"bi0001011b00010\/bi0001011b00010_1","volume-title":"Biochem. Biophys. Res. Commun. 133, 787\u221293","author":"Bicknell R.","year":"1985"},{"key":"bi0001011b00011\/bi0001011b00011_1","volume-title":"Biochem. Biophys. Res. Commun. 37, 333\u22129","author":"Latt S. A.","year":"1969"},{"key":"bi0001011b00012\/bi0001011b00012_1","first-page":"9","volume":"158","author":"Auld D. S.","year":"1988","journal-title":"Methods Enzymol."},{"key":"bi0001011b00013\/bi0001011b00013_1","volume-title":"Biochemistry 35, 15831\u22128","author":"Cha J.","year":"1996"},{"key":"bi0001011b00014\/bi0001011b00014_1","volume-title":"Biochemistry 2, 616\u2212622","author":"Simpson R. T.","year":"1963"},{"key":"bi0001011b00015\/bi0001011b00015_1","first-page":"62","volume":"50","author":"Latt S. A.","year":"1972","journal-title":"Anal. Biochem."},{"key":"bi0001011b00016\/bi0001011b00016_1","first-page":"6","volume":"183","author":"Ng M.","year":"1989","journal-title":"Anal. Biochem."},{"key":"bi0001011b00017\/bi0001011b00017_1","first-page":"12","volume":"158","author":"Holmquist B.","year":"1988","journal-title":"Methods Enzymol."},{"key":"bi0001011b00018\/bi0001011b00018_1","first-page":"4","volume":"158","author":"Auld D. S.","year":"1988","journal-title":"Methods Enzymol."},{"key":"bi0001011b00019\/bi0001011b00019_1","volume-title":"Anal. Biochem. 84, 370\u221283","author":"Tonomura B.","year":"1978"},{"key":"bi0001011b00020\/bi0001011b00020_1","volume-title":"Biochemistry 11, 3015\u221222","author":"Latt S. A.","year":"1972"},{"key":"bi0001011b00021\/bi0001011b00021_1","volume-title":"Adv. Enzymol. Relat. Areas Mol. Biol. 61, 201\u2212301","author":"Morrison J. F.","year":"1988"},{"key":"bi0001011b00022\/bi0001011b00022_1","volume-title":"Collect. Czech. Chem. Commun. 44, 725\u2212741","author":"Pollak M.","year":"1979"},{"key":"bi0001011b00023\/bi0001011b00023_1","volume-title":"Anal. Biochem. 146, 150\u22127","author":"Hunt J. B.","year":"1985"},{"key":"bi0001011b00024\/bi0001011b00024_1","volume-title":"Biochemistry 10, 4263\u221270","author":"Latt S. A.","year":"1971"},{"key":"bi0001011b00025\/bi0001011b00025_1","first-page":"86","volume":"52","author":"Banci L.","year":"1982","journal-title":"Struct. Bonding"},{"key":"bi0001011b00026\/bi0001011b00026_1","volume-title":"in Hydrolytic Enzymes","author":"Auld D. S.","year":"1987"},{"key":"bi0001011b00027\/bi0001011b00027_1","volume-title":"Proc. Natl. Acad. Sci. U.S.A. 76, 6216\u221220","author":"Holmquist B.","year":"1979"},{"key":"bi0001011b00028\/bi0001011b00028_1","volume-title":"Biochemistry 27, 1050\u22127","author":"Bicknell R.","year":"1988"},{"key":"bi0001011b00029\/bi0001011b00029_1","volume":"175","author":"Smith E. L.","year":"1949","journal-title":"J. Biol. Chem."},{"key":"bi0001011b00030\/bi0001011b00030_1","volume-title":"Arthritis Rheum. 30, 138\u221245","author":"Sheikh I. A.","year":"1987"},{"key":"bi0001011b00031\/bi0001011b00031_1","volume-title":"Methods Enzymol. 158, 110\u22124","author":"Auld D. S.","year":"1988"},{"key":"bi0001011b00032\/bi0001011b00032_1","volume-title":"Methods Enzymol. 248, 228\u221242","author":"Auld D. S.","year":"1995"},{"key":"bi0001011b00033\/bi0001011b00033_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0162-0134(00)80122-1","volume":"12","author":"Harrington P. C.","year":"1980","journal-title":"J. Inorg. Biochem."},{"key":"bi0001011b00034\/bi0001011b00034_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0162-0134(00)80288-3","volume":"14","author":"Hirose J.","year":"1981","journal-title":"J. Inorg. Biochem."},{"key":"bi0001011b00035\/bi0001011b00035_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0162-0134(00)80274-3","volume":"12","author":"Rogers R. J.","year":"1980","journal-title":"J. Inorg. Biochem."},{"key":"bi0001011b00036\/bi0001011b00036_1","volume-title":"Biochem. Biophys. Res. Commun. 176, 173\u22129","author":"Schwartz M. A.","year":"1991"},{"key":"bi0001011b00037\/bi0001011b00037_1","volume-title":"Biochemistry 22","author":"Geoghegan K. F.","year":"1983"},{"key":"bi0001011b00038\/bi0001011b00038_1","volume-title":"Biochemistry 31, 3840\u22126","author":"Auld D. S.","year":"1992"},{"key":"bi0001011b00039\/bi0001011b00039_1","volume-title":"Biochemistry 34, 16306\u221212","author":"Zhang K.","year":"1995"},{"key":"bi0001011b00040\/bi0001011b00040_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0021-9258(18)51564-7","volume":"264","author":"Christianson D. W.","year":"1989","journal-title":"J. Biol. Chem."},{"key":"bi0001011b00041\/bi0001011b00041_1","first-page":"22","volume":"2","author":"Johnson W. H.","year":"1987","journal-title":"J. Enzymol. Inhib."},{"key":"bi0001011b00042\/bi0001011b00042_1","volume-title":"Ann. Oncol. 6, 967\u221274","author":"Brown P. D.","year":"1995"},{"key":"bi0001011b00043\/bi0001011b00043_1","volume-title":"Funct., Genet. 31, 42\u221260.","author":"Garmer D. R.","year":"1998"},{"key":"bi0001011b00044\/bi0001011b00044_1","first-page":"60","volume":"878","author":"De B.","year":"1999","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"bi0001011b00045\/bi0001011b00045_1","doi-asserted-by":"crossref","DOI":"10.1021\/ja00131a004","volume":"117","author":"Kiefer L. L.","year":"1995","journal-title":"J. Am. Chem. Soc."},{"key":"bi0001011b00046\/bi0001011b00046_1","doi-asserted-by":"crossref","DOI":"10.1021\/ja00131a005","volume":"117","author":"Lesburg C. A.","year":"1995","journal-title":"J. Am. Chem. Soc."},{"key":"bi0001011b00047\/bi0001011b00047_1","volume-title":"Acc. Chem. Res. 29, 331\u221239","author":"Christianson D. W.","year":"1996"},{"key":"bi0001011b00048\/bi0001011b00048_1","author":"Canzoniero L. M.","year":"1999","journal-title":"J. Neurosci. 19, RC31 (1\u22126)."},{"key":"bi0001011b00049\/bi0001011b00049_1","doi-asserted-by":"crossref","DOI":"10.1146\/annurev.nu.05.070185.002013","volume":"5","author":"Prasad A. S.","year":"1985","journal-title":"Annu. Rev. Nutr."},{"key":"bi0001011b00050\/bi0001011b00050_1","volume-title":"Toxicol. Appl. Pharmacol. 80, 467\u221272","author":"Goering P. L.","year":"1985"},{"key":"bi0001011b00051\/bi0001011b00051_1","volume-title":"Arch. Toxicol. 56, 247\u221251","author":"Heilmaier H. E.","year":"1985"},{"key":"bi0001011b00052\/bi0001011b00052_1","first-page":"7","volume":"2","author":"Mullin C. H.","year":"1988","journal-title":"J. Trace Elem. Electrolytes Health Dis."},{"key":"bi0001011b00053\/bi0001011b00053_1","volume":"120","author":"Yuzbasiyan-Gurkan V.","year":"1992","journal-title":"J. Lab. Clin. Med."},{"key":"bi0001011b00054\/bi0001011b00054_1","volume":"109","author":"Brewer G. J.","year":"1987","journal-title":"J. Lab. Clin. Med."},{"key":"bi0001011b00055\/bi0001011b00055_1","volume-title":"Medicine (Baltimore) 71, 139\u221264","author":"Brewer G. J.","year":"1992"},{"key":"bi0001011b00056\/bi0001011b00056_1","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/bdd.2510010205","volume":"1","author":"Crawhall J. C.","year":"1979","journal-title":"Biopharm. Drug Dispos."},{"key":"bi0001011b00057\/bi0001011b00057_1","doi-asserted-by":"crossref","DOI":"10.1172\/JCI108526","volume":"58","author":"Sapolsky A. I.","year":"1976","journal-title":"J. Clin. Invest."},{"key":"bi0001011b00058\/bi0001011b00058_1","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/BF02231681","volume":"15","author":"Norga K.","year":"1996","journal-title":"Clin. Rheumatol."},{"key":"bi0001011n00001\/bi0001011n00001_1","volume-title":"angiotensin converting enzyme","author":"Abbreviations ACE"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi000101%2B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T23:03:37Z","timestamp":1643843017000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi000101%2B"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,5,31]]},"references-count":59,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2000,6,1]]}},"alternative-id":["10.1021\/bi000101+"],"URL":"https:\/\/doi.org\/10.1021\/bi000101+","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,5,31]]}}}