{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T05:00:53Z","timestamp":1788843653327,"version":"build-2803163510"},"reference-count":28,"publisher":"American Chemical Society (ACS)","issue":"38","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2001,9,1]]},"DOI":"10.1021\/bi010673+","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T06:08:28Z","timestamp":1027663708000},"page":"11453-11459","source":"Crossref","is-referenced-by-count":54,"title":["Anion Shielding of Electrostatic Repulsions in Transthyretin Modulates Stability and Amyloidosis:\u2009 Insight into the Chaotrope Unfolding Dichotomy"],"prefix":"10.1021","volume":"40","author":[{"given":"Per","family":"Hammarstr\u00f6m","sequence":"first","affiliation":[{"name":"Department of Chemistry and The Skaggs Institute of Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC265, La Jolla, California 92037"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Chemistry and The Skaggs Institute of Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC265, La Jolla, California 92037"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songpon","family":"Deechongkit","sequence":"additional","affiliation":[{"name":"Department of Chemistry and The Skaggs Institute of Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC265, La Jolla, California 92037"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery W.","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Chemistry and The Skaggs Institute of Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, BCC265, La Jolla, California 92037"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2001,8,25]]},"reference":[{"key":"bi0106731b00001\/bi0106731b00001_1","volume-title":"Biochemistry 31, 8654\u22128660","author":"Colon W.","year":"1992"},{"key":"bi0106731b00002\/bi0106731b00002_1","volume-title":"Biochemistry 35, 6470\u22126482","author":"Lai Z.","year":"1996"},{"key":"bi0106731b00003\/bi0106731b00003_1","volume-title":"Nature 385, 787\u2212793","author":"Booth D. R.","year":"1997"},{"key":"bi0106731b00004\/bi0106731b00004_1","volume-title":"Biochemistry 40, 3525\u22123535","author":"Khurana R.","year":"2001"},{"key":"bi0106731b00005\/bi0106731b00005_1","volume-title":"Biochemistry 39, 8735\u22128746","author":"McParland V. J.","year":"2000"},{"key":"bi0106731b00006\/bi0106731b00006_1","doi-asserted-by":"crossref","DOI":"10.1006\/jmbi.2000.4478","volume":"307","author":"Chiti F.","year":"2001","journal-title":"J. Mol. Biol."},{"key":"bi0106731b00007\/bi0106731b00007_1","volume-title":"Hum. Mutat. 5, 191\u2212196","author":"Saraiva M. J. M.","year":"1995"},{"key":"bi0106731b00008\/bi0106731b00008_1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0959-440X(96)80089-3","volume":"6","author":"Kelly J. W.","year":"1996","journal-title":"Curr. Opin. Struct. Biol."},{"key":"bi0106731b00009\/bi0106731b00009_1","volume-title":"Curr. Opin. Struct. Biol. 8, 101\u2212106","author":"Kelly J. W.","year":"1998"},{"key":"bi0106731b00010\/bi0106731b00010_1","volume-title":"Biochemistry 36, 10230\u221210239","author":"Lai Z.","year":"1997"},{"key":"bi0106731b00011\/bi0106731b00011_1","volume-title":"Gene 151, 119\u2212123","author":"Weiner M. P.","year":"1994"},{"key":"bi0106731b00012\/bi0106731b00012_1","volume-title":"Biochemistry 40, 11442\u221211452","author":"Jiang X.","year":"2001"},{"key":"bi0106731b00013\/bi0106731b00013_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0021-9258(20)79739-5","volume":"249","author":"Greene R. F.","year":"1974","journal-title":"J. Biol. Chem."},{"key":"bi0106731b00014\/bi0106731b00014_1","volume-title":"Protein Sci. 10, 1606\u22121613","author":"Schneider F.","year":"2001"},{"key":"bi0106731b00015\/bi0106731b00015_1","volume-title":"Proc. Natl. Acad. Sci. U.S.A. 95, 12956\u221212960","author":"Peterson S. A.","year":"1998"},{"key":"bi0106731b00016\/bi0106731b00016_1","volume-title":"Nat. Struct. Biol. 7, 312\u2212321","author":"Klabunde T.","year":"2000"},{"key":"bi0106731b00017\/bi0106731b00017_1","volume-title":"Nature 356, 263\u2212265","author":"Baker D.","year":"1992"},{"key":"bi0106731b00018\/bi0106731b00018_1","volume-title":"Nature 395, 817\u2212819","author":"Sohl J. L.","year":"1998"},{"key":"bi0106731b00019\/bi0106731b00019_1","first-page":"42","volume":"1316","author":"Bonifacio M. J.","year":"1996","journal-title":"Biochim. Biophys. Acta"},{"key":"bi0106731b00020\/bi0106731b00020_1","volume-title":"Biochemistry 14, 3401\u22123408","author":"Norne J. E.","year":"1975"},{"key":"bi0106731b00021\/bi0106731b00021_1","volume-title":"Biochemistry 17, 3774\u22123781","author":"Halle B.","year":"1978"},{"key":"bi0106731b00022\/bi0106731b00022_1","doi-asserted-by":"crossref","DOI":"10.1006\/jmbi.1993.1530","volume":"233","author":"Perutz M. F.","year":"1993","journal-title":"J. Mol. Biol."},{"key":"bi0106731b00023\/bi0106731b00023_1","doi-asserted-by":"crossref","DOI":"10.1006\/jmbi.1994.1394","volume":"239","author":"Perutz M. F.","year":"1994","journal-title":"J. Mol. Biol."},{"key":"bi0106731b00024\/bi0106731b00024_1","doi-asserted-by":"crossref","DOI":"10.1006\/jmbi.1994.1395","volume":"239","author":"Bonaventura C.","year":"1994","journal-title":"J. Mol. Biol."},{"key":"bi0106731b00025\/bi0106731b00025_1","volume-title":"Biochemistry 39, 14839\u221214846","author":"Kim T. D.","year":"2000"},{"key":"bi0106731b00026\/bi0106731b00026_1","volume":"121","author":"Blake C. C. F.","year":"1978","journal-title":"J. Mol. Biol."},{"key":"bi0106731b00027\/bi0106731b00027_1","volume-title":"Proc. Natl. Acad. Sci. U.S.A. 97, 6445\u22126450","author":"Ferrao-Gonzaes A. D.","year":"2000"},{"key":"bi0106731n00001\/bi0106731n00001_1","volume-title":"wild type transthyretin","author":"Abbreviations TTR"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi010673%2B","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T03:00:49Z","timestamp":1643857249000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi010673%2B"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,8,25]]},"references-count":28,"journal-issue":{"issue":"38","published-print":{"date-parts":[[2001,9,1]]}},"alternative-id":["10.1021\/bi010673+"],"URL":"https:\/\/doi.org\/10.1021\/bi010673+","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,8,25]]}}}