{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T17:10:01Z","timestamp":1771002601649,"version":"3.50.1"},"reference-count":44,"publisher":"American Chemical Society (ACS)","issue":"24","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2004,6,1]]},"DOI":"10.1021\/bi0360758","type":"journal-article","created":{"date-parts":[[2004,6,15]],"date-time":"2004-06-15T18:37:29Z","timestamp":1087324649000},"page":"7663-7671","source":"Crossref","is-referenced-by-count":25,"title":["Three-Dimensional Structure of Human Adenine Phosphoribosyltransferase and Its Relation to DHA-Urolithiasis<sup>,<\/sup>"],"prefix":"10.1021","volume":"43","author":[{"given":"Marcio","family":"Silva","sequence":"first","affiliation":[{"name":"Laboratory of Protein Crystallography and Structural Biology, Physics Institute of S\u00e3o Carlos, University of S\u00e3o Paulo, Av. Trabalhador S\u00e3ocarlense 400, P.O. Box 369, 13566-590 S\u00e3o Carlos, SP, Brazil, and Department of Chemistry, Biotechnology Center, State University of Ponta Grossa, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos Henrique Tomich de Paula","family":"Silva","sequence":"additional","affiliation":[{"name":"Laboratory of Protein Crystallography and Structural Biology, Physics Institute of S\u00e3o Carlos, University of S\u00e3o Paulo, Av. Trabalhador S\u00e3ocarlense 400, P.O. Box 369, 13566-590 S\u00e3o Carlos, SP, Brazil, and Department of Chemistry, Biotechnology Center, State University of Ponta Grossa, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Iulek","sequence":"additional","affiliation":[{"name":"Laboratory of Protein Crystallography and Structural Biology, Physics Institute of S\u00e3o Carlos, University of S\u00e3o Paulo, Av. Trabalhador S\u00e3ocarlense 400, P.O. Box 369, 13566-590 S\u00e3o Carlos, SP, Brazil, and Department of Chemistry, Biotechnology Center, State University of Ponta Grossa, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Otavio Henrique","family":"Thiemann","sequence":"additional","affiliation":[{"name":"Laboratory of Protein Crystallography and Structural Biology, Physics Institute of S\u00e3o Carlos, University of S\u00e3o Paulo, Av. Trabalhador S\u00e3ocarlense 400, P.O. Box 369, 13566-590 S\u00e3o Carlos, SP, Brazil, and Department of Chemistry, Biotechnology Center, State University of Ponta Grossa, PR, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2004,5,25]]},"reference":[{"key":"bi0360758b00001\/bi0360758b00001_1","volume-title":"in The Metabolic and Molecular Bases of Inherited Disease","author":"Simmonds H. A.","year":"1995"},{"key":"bi0360758b00002\/bi0360758b00002_1","volume-title":"Proc. Natl. Acad. Sci. U.S.A. 93","author":"Engle S. J.","year":"1996"},{"key":"bi0360758b00003\/bi0360758b00003_1","volume-title":"Biochem. Pharmacol. 31, 277\u2212288.","author":"Williams-Ashman H. G.","year":"1982"},{"key":"bi0360758b00004\/bi0360758b00004_1","volume-title":"Eur. J. Pediatr. 138, 346\u2212349.","author":"Greenwood M. C.","year":"1982"},{"key":"bi0360758b00005\/bi0360758b00005_1","doi-asserted-by":"crossref","DOI":"10.1172\/JCI115825","volume":"90","author":"Kamatani N.","year":"1992","journal-title":"J. Clin. Invest."},{"key":"bi0360758b00006\/bi0360758b00006_1","doi-asserted-by":"crossref","DOI":"10.1007\/978-94-011-3911-3","volume-title":"in Purines:\u2009 Basic and Clinical Aspects","author":"Stone T. W.","year":"1991"},{"key":"bi0360758b00007\/bi0360758b00007_1","volume-title":"Arch. Biochem. Biophys. 70, 150\u2212156.","author":"Wyngaarden J. B.","year":"1957"},{"key":"bi0360758b00008\/bi0360758b00008_1","volume-title":"Ciba Found. Symp. 48","author":"De Vries A.","year":"1977"},{"key":"bi0360758b00009\/bi0360758b00009_1","volume":"277","author":"Shi W.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"bi0360758b00010\/bi0360758b00010_1","doi-asserted-by":"crossref","DOI":"10.1093\/emboj\/18.13.3533","volume":"18","author":"Phillips C. L.","year":"1999","journal-title":"EMBO J."},{"key":"bi0360758b00011\/bi0360758b00011_1","volume-title":"Biochemistry 37, 17120\u221217127.","author":"Focia P. J.","year":"1998"},{"key":"bi0360758b00012\/bi0360758b00012_1","volume":"282","author":"Vos S.","year":"1998","journal-title":"J. Mol. Biol."},{"key":"bi0360758b00013\/bi0360758b00013_1","volume-title":"Nat. Struct. Biol. 6, 588\u2212593.","author":"Shi W.","year":"1999"},{"key":"bi0360758b00014\/bi0360758b00014_1","volume-title":"Proc. Natl. Acad. Sci. U.S.A. 76 (2), 615\u2212619","author":"Vogelstein B.","year":"1979"},{"key":"bi0360758b00015\/bi0360758b00015_1","volume-title":"in Short Protocols in Molecular Biology","author":"Ausubel F. M.","year":"1995"},{"key":"bi0360758b00016\/bi0360758b00016_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0021-9258(19)86119-7","volume":"255","author":"Tuttle J. V.","year":"1980","journal-title":"J. Biol. Chem."},{"key":"bi0360758b00017\/bi0360758b00017_1","volume-title":"Acta Crystallogr. D58, 167\u2212169.","author":"Del Sol F. G.","year":"2002"},{"key":"bi0360758b00018\/bi0360758b00018_1","volume-title":"Acta Crystallogr. D50, 760\u2212763.","author":"Chang G.","year":"1994"},{"key":"bi0360758b00019\/bi0360758b00019_1","doi-asserted-by":"crossref","DOI":"10.1107\/S0108767393007597","volume":"50","author":"Navaza J.","year":"1994","journal-title":"Acta Crystallogr."},{"key":"bi0360758b00020\/bi0360758b00020_1","author":"Silva M.","year":"2004","journal-title":"Biochim. Biophys. Acta (in press)."},{"key":"bi0360758b00021\/bi0360758b00021_1","volume-title":"Acta Crystallogr. 54, 905\u2212921.","author":"Brunger A. T.","year":"1998"},{"key":"bi0360758b00022\/bi0360758b00022_1","volume-title":"Acta Crystallogr. 53, 240\u2212255.","author":"Murshudov G. N.","year":"1997"},{"key":"bi0360758b00023\/bi0360758b00023_1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/0263-7855(92)80022-6","volume":"10","author":"McRee D. E.","year":"1992","journal-title":"J. Mol. Graphics"},{"key":"bi0360758b00024\/bi0360758b00024_1","volume-title":"Nat. Struct. Biol. 6, 458\u2212463.","author":"Perrakis A.","year":"1999"},{"key":"bi0360758b00025\/bi0360758b00025_1","volume":"47","author":"Jones T. A.","year":"1991","journal-title":"Acta Crystallogr."},{"key":"bi0360758b00026\/bi0360758b00026_1","volume-title":"Trends Biochem. Sci. 19, 258\u2212260.","author":"Appel R. D.","year":"1994"},{"key":"bi0360758b00027\/bi0360758b00027_1","volume":"248","author":"Thomas C. B.","year":"1973","journal-title":"J. Biol. Chem."},{"key":"bi0360758b00028\/bi0360758b00028_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0021-9258(18)50267-2","volume":"254","author":"Holden J. A.","year":"1979","journal-title":"J. Biol. Chem."},{"key":"bi0360758b00029\/bi0360758b00029_1","volume":"884","author":"Okoda G.","year":"1986","journal-title":"Biochim. Biophys. Acta"},{"key":"bi0360758b00030\/bi0360758b00030_1","doi-asserted-by":"crossref","DOI":"10.1006\/jmbi.1996.0081","volume":"256","author":"Nayal M.","year":"1996","journal-title":"J. Mol. Biol."},{"key":"bi0360758b00031\/bi0360758b00031_1","volume-title":"in International Table for Crystallography","author":"Kleywegt G. J.","year":"2001"},{"key":"bi0360758b00032\/bi0360758b00032_1","doi-asserted-by":"crossref","DOI":"10.1006\/jmbi.1998.2393","volume":"285","author":"Kleywegt G. J.","year":"1999","journal-title":"J. Mol. Biol."},{"key":"bi0360758b00033\/bi0360758b00033_1","volume-title":"Biochemistry 40, 10800\u221210809.","author":"Shi W.","year":"2001"},{"key":"bi0360758b00034\/bi0360758b00034_1","volume-title":"A common structural framework for adenine and AMP binding in 13 unrelated protein families","author":"Denessiouk K. A.","year":"2000"},{"key":"bi0360758b00035\/bi0360758b00035_1","volume-title":"Nucleic Acids Res. 29, 4294\u22124309.","author":"Nobeli I.","year":"2001"},{"key":"bi0360758b00036\/bi0360758b00036_1","volume-title":"Biochemistry 34, 10744\u221210754.","author":"Scapin G.","year":"1995"},{"key":"bi0360758b00037\/bi0360758b00037_1","volume-title":"Cell 78, 325\u2212334.","author":"Eads J. C.","year":"1994"},{"key":"bi0360758b00038\/bi0360758b00038_1","volume-title":"Biochemistry 35, 7032\u22127040.","author":"Somoza J. R.","year":"1996"},{"key":"bi0360758b00039\/bi0360758b00039_1","volume-title":"Biochemistry 35, 3803\u22123809.","author":"Henriksen A.","year":"1996"},{"key":"bi0360758b00040\/bi0360758b00040_1","volume":"18","author":"Schumacher M. A.","year":"1998","journal-title":"EMBO J."},{"key":"bi0360758b00041\/bi0360758b00041_1","first-page":"A152","volume":"47","author":"Chen J.","year":"1990","journal-title":"Am. J. Hum. Genet."},{"key":"bi0360758b00042\/bi0360758b00042_1","volume-title":"Hum. Mol. Genet. 3, 817\u2212818.","author":"Sahota A.","year":"1994"},{"key":"bi0360758b00043\/bi0360758b00043_1","doi-asserted-by":"crossref","DOI":"10.1172\/JCI113408","volume":"81","author":"Hidaka Y.","year":"1988","journal-title":"J. Clin. Invest."},{"key":"bi0360758n00001\/bi0360758n00001_1","volume-title":"adenine phosphoribosyltransferase","author":"Abbreviations APRT"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi0360758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,6]],"date-time":"2023-03-06T18:25:17Z","timestamp":1678127117000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi0360758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5,25]]},"references-count":44,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2004,6,1]]}},"alternative-id":["10.1021\/bi0360758"],"URL":"https:\/\/doi.org\/10.1021\/bi0360758","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,5,25]]}}}