{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T18:53:35Z","timestamp":1772132015347,"version":"3.50.1"},"reference-count":30,"publisher":"American Chemical Society (ACS)","issue":"29","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2006,7,1]]},"DOI":"10.1021\/bi060455m","type":"journal-article","created":{"date-parts":[[2006,6,30]],"date-time":"2006-06-30T13:18:24Z","timestamp":1151673504000},"page":"8972-8977","source":"Crossref","is-referenced-by-count":35,"title":["Efficient Substrate Cleavage Catalyzed by Hammerhead Ribozymes Derivatized with Selenium for X-Ray Crystallography"],"prefix":"10.1021","volume":"45","author":[{"given":"Gary","family":"Brandt","sequence":"first","affiliation":[{"name":"Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, and Brooklyn College, Brooklyn, New York 11210"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Carrasco","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, and Brooklyn College, Brooklyn, New York 11210"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Georgia State University, Atlanta, Georgia 30303, and Brooklyn College, Brooklyn, New York 11210"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2006,6,30]]},"reference":[{"key":"bi060455mb00001\/bi060455mb00001_1","volume-title":"Science 296, 1260\u22121263.","author":"Storz G.","year":"2002"},{"key":"bi060455mb00002\/bi060455mb00002_1","volume":"2","author":"Eddy S. R.","year":"2001","journal-title":"Nat. Rev. Gen."},{"key":"bi060455mb00003\/bi060455mb00003_1","volume-title":"ChemBioChem 6, 1492\u22121505.","author":"Lathan M. P.","year":"2005"},{"key":"bi060455mb00004\/bi060455mb00004_1","doi-asserted-by":"crossref","DOI":"10.1146\/annurev.biophys.34.122004.184428","volume":"34","author":"Blount K. F.","year":"2005","journal-title":"Rev. Biophys. Biomol. Struct."},{"key":"bi060455mb00005\/bi060455mb00005_1","volume-title":"RNA 2, 395\u2212403.","author":"McKay D. B.","year":"1996"},{"key":"bi060455mb00006\/bi060455mb00006_1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/(SICI)1097-0282(1997)44:1<3::AID-BIP2>3.0.CO;2-Z","volume":"44","author":"Holbrook S. R.","year":"1997","journal-title":"Biopolymers"},{"key":"bi060455mb00007\/bi060455mb00007_1","volume-title":"Curr. Opin. Chem. Biol. 8, 580\u2212591.","author":"Egli M.","year":"2004"},{"key":"bi060455mb00008\/bi060455mb00008_1","volume-title":"Nature 395, 567\u2212574.","author":"Ferre-D'Amare A. R.","year":"1998"},{"key":"bi060455mb00009\/bi060455mb00009_1","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.ymeth.2004.03.027","volume":"34","author":"Ke A.","year":"2004","journal-title":"Methods"},{"key":"bi060455mb00010\/bi060455mb00010_1","volume-title":"Science 249, 1398\u22121405.","author":"Yang W.","year":"1990"},{"key":"bi060455mb00011\/bi060455mb00011_1","volume-title":"Trends Biochem. Sci. 25, 637\u2212643.","author":"Hendrickson W. A.","year":"2000"},{"key":"bi060455mb00012\/bi060455mb00012_1","volume-title":"Nucleosides, Nucleotides Nucleic Acids 20, 1723\u22121734.","author":"Carrasco N.","year":"2001"},{"key":"bi060455mb00013\/bi060455mb00013_1","first-page":"25","volume":"124","author":"Du W.","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"bi060455mb00014\/bi060455mb00014_1","volume-title":"Biochimie 84, 849\u2212858.","author":"Teplova M.","year":"2002"},{"key":"bi060455mb00015\/bi060455mb00015_1","doi-asserted-by":"crossref","DOI":"10.1021\/ol0365077","volume":"6","author":"Buzin Y.","year":"2004","journal-title":"Org. Lett."},{"key":"bi060455mb00016\/bi060455mb00016_1","volume-title":"Nucleic Acids Res. 32, 1638\u22121640.","author":"Carrasco N.","year":"2004"},{"key":"bi060455mb00017\/bi060455mb00017_1","doi-asserted-by":"crossref","DOI":"10.1021\/ja0383221","volume":"126","author":"Carrasco N.","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"bi060455mb00018\/bi060455mb00018_1","volume-title":"Angew. Chem. 118, 100\u2212103. Carrasco, N.","author":"Carrasco N.","year":"2006"},{"key":"bi060455mb00019\/bi060455mb00019_1","volume":"124","author":"Wilds C. J.","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"bi060455mb00020\/bi060455mb00020_1","volume-title":"Nat. Struct. Mol. Biol. 12, 218\u2212224.","author":"Serganov A.","year":"2005"},{"key":"bi060455mb00021\/bi060455mb00021_1","doi-asserted-by":"crossref","DOI":"10.1021\/jo00264a024","volume":"54","author":"Ludwig J.","year":"1989","journal-title":"J. Org. Chem."},{"key":"bi060455mb00022\/bi060455mb00022_1","volume-title":"Proc. Natl. Acad. Sci. U.S.A. 75","author":"Burgers P. M.","year":"1978"},{"key":"bi060455mb00023\/bi060455mb00023_1","volume-title":"Nucleic Acids Res. 15, 4145\u22124162.","author":"Griffiths A. D.","year":"1987"},{"key":"bi060455mb00024\/bi060455mb00024_1","doi-asserted-by":"crossref","DOI":"10.1111\/j.1432-1033.1970.tb00961.x","volume":"13","author":"Eckstein F.","year":"1970","journal-title":"Eur. J. Biochem."},{"key":"bi060455mb00025\/bi060455mb00025_1","doi-asserted-by":"crossref","DOI":"10.1016\/0014-5793(69)80037-2","volume":"2","author":"Eckstein F.","year":"1969","journal-title":"FEBS Lett."},{"key":"bi060455mb00026\/bi060455mb00026_1","volume-title":"Nucleic Acids Res. 32, 5991\u22126000.","author":"Hall A. H. S.","year":"2004"},{"key":"bi060455mb00027\/bi060455mb00027_1","volume-title":"Nature 372, 111\u2212113.","author":"Pley H. W.","year":"1994"},{"key":"bi060455mb00028\/bi060455mb00028_1","volume-title":"Cell 81, 991\u22121002.","author":"Scott W. G.","year":"1995"},{"key":"bi060455mb00029\/bi060455mb00029_1","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.272.43.26822","volume":"272","author":"Peracchi A.","year":"1997","journal-title":"J. Biol. Chem."},{"key":"bi060455mb00030\/bi060455mb00030_1","volume-title":"Nucleic Acids Res. 18, 6025\u22126029.","author":"Ruffner D. E.","year":"1990"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi060455m","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T17:37:19Z","timestamp":1680197839000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi060455m"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6,30]]},"references-count":30,"journal-issue":{"issue":"29","published-print":{"date-parts":[[2006,7,1]]}},"alternative-id":["10.1021\/bi060455m"],"URL":"https:\/\/doi.org\/10.1021\/bi060455m","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1033337.375275","asserted-by":"object"}]},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6,30]]}}}