{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T02:20:12Z","timestamp":1777429212826,"version":"3.51.4"},"reference-count":44,"publisher":"American Chemical Society (ACS)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2011,4,12]]},"DOI":"10.1021\/bi101908m","type":"journal-article","created":{"date-parts":[[2011,3,10]],"date-time":"2011-03-10T17:22:04Z","timestamp":1299777724000},"page":"2808-2819","source":"Crossref","is-referenced-by-count":46,"title":["Heterogeneous Amylin Fibril Growth Mechanisms Imaged by Total Internal Reflection Fluorescence Microscopy"],"prefix":"10.1021","volume":"50","author":[{"given":"Sharadrao M.","family":"Patil","sequence":"first","affiliation":[{"name":"Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269-3125, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269-3125, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suman","family":"Jha","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269-3125, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei T.","family":"Alexandrescu","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut 06269-3125, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2011,3,21]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0140-6736(87)90825-7","volume":"2","author":"Clark A.","year":"1987","journal-title":"Lancet"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s00125-003-1304-4","volume":"47","author":"Clark A.","year":"2004","journal-title":"Diabetologia"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1210\/edrv-15-2-163","volume":"15","author":"Cooper G. J.","year":"1994","journal-title":"Endocr. Rev."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1007\/s00018-009-9070-1","volume":"66","author":"Gotz J.","year":"2009","journal-title":"Cell. Mol. Life Sci."},{"key":"ref5\/cit5","first-page":"169","volume":"6","author":"Zdrojewicz Z.","year":"2006","journal-title":"Diabetol. Dosw. Klin."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2337\/diabetes.48.3.491","volume":"48","author":"Janson J.","year":"1999","journal-title":"Diabetes"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/368756a0","volume":"368","author":"Lorenzo A.","year":"1994","journal-title":"Nature"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1093\/ilar.47.3.225","volume":"47","author":"Matveyenko A. V.","year":"2006","journal-title":"ILAR J."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"11338","DOI":"10.1021\/bi020314u","volume":"41","author":"Anguiano M.","year":"2002","journal-title":"Biochemistry"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chemphyslip.2009.03.008","volume":"160","author":"Engel M. F.","year":"2009","journal-title":"Chem. Phys. Lipids"},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1210\/er.2007-0037","volume":"29","author":"Haataja L.","year":"2008","journal-title":"Endocr. Rev."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"6016","DOI":"10.1021\/bi702518m","volume":"47","author":"Meng F.","year":"2008","journal-title":"Biochemistry"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.2337\/diab.45.9.1279","volume":"45","author":"Sakagashira S.","year":"1996","journal-title":"Diabetes"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"242","DOI":"10.3109\/13506120108993820","volume":"8","author":"Ma Z.","year":"2001","journal-title":"Amyloid"},{"issue":"5","key":"ref15\/cit15","first-page":"S1","volume":"14","author":"Amos A. F.","year":"1997","journal-title":"Diabet. Med."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"917","DOI":"10.2337\/diacare.26.3.917","volume":"26","author":"Hogan P.","year":"2003","journal-title":"Diabetes Care"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0076-6879(06)13005-0","volume":"413","author":"Ban T.","year":"2006","journal-title":"Methods Enzymol."},{"key":"ref18\/cit18","volume":"12","author":"Fish K. N.","year":"2009","journal-title":"Curr. Protoc. Cytom. Chapter"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.copbio.2004.12.004","volume":"16","author":"Schneckenburger H.","year":"2005","journal-title":"Curr. Opin. Biotechnol."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1016\/j.bpj.2008.11.024","volume":"96","author":"Andersen C. B.","year":"2009","journal-title":"Biophys. J."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"16462","DOI":"10.1074\/jbc.C300049200","volume":"278","author":"Ban T.","year":"2003","journal-title":"J. Biol. Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.jmb.2004.09.078","volume":"344","author":"Ban T.","year":"2004","journal-title":"J. Mol. Biol."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1074\/jbc.M805118200","volume":"284","author":"Ozawa D.","year":"2009","journal-title":"J. Biol. Chem."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1002\/pro.5560020312","volume":"2","author":"LeVine H.","year":"1993","journal-title":"Protein Sci."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"e321","DOI":"10.1371\/journal.pbio.0020321","volume":"2","author":"Collins S. R.","year":"2004","journal-title":"PLoS Biol."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"35227","DOI":"10.1074\/jbc.C100304200","volume":"276","author":"Inoue Y.","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"6306","DOI":"10.1021\/ja910964c","volume":"132","author":"Liang Y.","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"16284","DOI":"10.1021\/bi051432v","volume":"44","author":"Abedini A.","year":"2005","journal-title":"Biochemistry"},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/0022-2836(85)90175-5","volume":"183","author":"Ferrone F. A.","year":"1985","journal-title":"J. Mol. Biol."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"4694","DOI":"10.1021\/bi0160462","volume":"41","author":"Padrick S. B.","year":"2002","journal-title":"Biochemistry"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"12341","DOI":"10.1073\/pnas.0703306104","volume":"104","author":"Ruschak A. M.","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref32\/cit32","first-page":"36","volume":"11","author":"Abramoff M. D.","year":"2004","journal-title":"Biophoton. Int."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"12206","DOI":"10.1074\/jbc.M312452200","volume":"279","author":"Green J. D.","year":"2004","journal-title":"J. Biol. Chem."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"6071","DOI":"10.1074\/jbc.M109.069542","volume":"285","author":"Wu J. W.","year":"2010","journal-title":"J. Biol. Chem."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1038\/nature02261","volume":"426","author":"Dobson C. M.","year":"2003","journal-title":"Nature"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1006\/jmbi.1998.2299","volume":"285","author":"Goldsbury C.","year":"1999","journal-title":"J. Mol. Biol."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1146\/annurev.biochem.66.1.385","volume":"66","author":"Harper J. D.","year":"1997","journal-title":"Annu. Rev. Biochem."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1021\/bi011711s","volume":"41","author":"Cohlberg J. A.","year":"2002","journal-title":"Biochemistry"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/j.jmb.2006.12.044","volume":"366","author":"Volles M. J.","year":"2007","journal-title":"J. Mol. Biol."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0006-3495(02)75404-0","volume":"82","author":"Ferrone F. A.","year":"2002","journal-title":"Biophys. J."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1110\/ps.041266605","volume":"14","author":"Hortschansky P.","year":"2005","journal-title":"Protein Sci."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1126\/science.1178250","volume":"326","author":"Knowles T. P.","year":"2009","journal-title":"Science"},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"8926","DOI":"10.1073\/pnas.0711664105","volume":"105","author":"Xue W. F.","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"10830","DOI":"10.1021\/jp810972y","volume":"113","author":"Fodera V.","year":"2009","journal-title":"J. Phys. Chem. B"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi101908m","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T08:24:54Z","timestamp":1682151894000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi101908m"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3,21]]},"references-count":44,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2011,4,12]]}},"alternative-id":["10.1021\/bi101908m"],"URL":"https:\/\/doi.org\/10.1021\/bi101908m","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,3,21]]}}}