{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T18:48:56Z","timestamp":1759776536146},"reference-count":72,"publisher":"American Chemical Society (ACS)","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2011,6,7]]},"DOI":"10.1021\/bi2000752","type":"journal-article","created":{"date-parts":[[2011,5,5]],"date-time":"2011-05-05T17:28:17Z","timestamp":1304616497000},"page":"4843-4854","source":"Crossref","is-referenced-by-count":7,"title":["Dynamics of a Heparin-Binding Domain of VEGF<sub>165<\/sub> Complexed with Its Inhibitor Triamterene"],"prefix":"10.1021","volume":"50","author":[{"given":"Ki-Woong","family":"Jeong","sequence":"first","affiliation":[{"name":"Department of Bioscience and Biotechnology and Bio\/Molecular Informatics Center, Konkuk University, Seoul 143-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jee-Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Bioscience and Biotechnology and Bio\/Molecular Informatics Center, Konkuk University, Seoul 143-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Ah","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Bioscience and Biotechnology and Bio\/Molecular Informatics Center, Konkuk University, Seoul 143-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung-Pil","family":"Yang","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Science and Technology, Konkuk University, Seoul 143-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyunsook","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Bioscience and Biotechnology and Bio\/Molecular Informatics Center, Konkuk University, Seoul 143-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Il","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Konkuk University, Seoul 143-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Bom","family":"Chae","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Science and Technology, Konkuk University, Seoul 143-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangmee","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Bioscience and Biotechnology and Bio\/Molecular Informatics Center, Konkuk University, Seoul 143-701, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2011,5,13]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0896-6273(00)80115-4","volume":"16","author":"Yankner B. A.","year":"1996","journal-title":"Neuron"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1126\/science.1072994","volume":"297","author":"Hardy J.","year":"2002","journal-title":"Science"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S1471-4892(01)00126-6","volume":"2","author":"Sommer B.","year":"2002","journal-title":"Curr. Opin. Pharmacol."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0197-4580(03)00111-8","volume":"25","author":"Yang S.-P.","year":"2004","journal-title":"Neurobiol. Aging"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.1471-4159.2004.02993.x","volume":"93","author":"Yang S.-P.","year":"2005","journal-title":"J. Neurochem."},{"key":"ref6\/cit6","first-page":"1029","volume":"146","author":"Dvorak H. F.","year":"1995","journal-title":"Am. J. Pathol."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00666035","volume":"36","author":"Ferrara N.","year":"1995","journal-title":"Breast Cancer Res. Treat."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/380435a0","volume":"380","author":"Carmeliet P.","year":"1996","journal-title":"Nature"},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/380439a0","volume":"380","author":"Ferrara N.","year":"1996","journal-title":"Nature"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/nm0195-27","volume":"1","author":"Folkman J.","year":"1995","journal-title":"Nature Med."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1385\/JMN:14:3:197","volume":"14","author":"Jin K. L.","year":"2000","journal-title":"J. Mol. Neurosci."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"10242","DOI":"10.1073\/pnas.97.18.10242","volume":"97","author":"Jin K. L.","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1172\/JCI20682","volume":"113","author":"Storkebaum E.","year":"2004","journal-title":"J. Cin. Invest."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/S0969-2126(97)00284-0","volume":"5","author":"Muller Y. A.","year":"1997","journal-title":"Structure"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1146\/annurev.bb.24.060195.001413","volume":"24","author":"Sun P. D.","year":"1995","journal-title":"Annu. Rev. Biophys. Biomol. Struct."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/0092-8674(93)90127-C","volume":"73","author":"McDonald N. Q.","year":"1993","journal-title":"Cell"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0969-2126(93)90029-G","volume":"1","author":"Murray-Rust J.","year":"1993","journal-title":"Structure"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/0959-440X(95)80102-2","volume":"5","author":"Isaacs N. W.","year":"1995","journal-title":"Curr. Opin. Struct. Biol."},{"key":"ref19\/cit19","first-page":"11","volume":"1","author":"Ferrara N.","year":"2009","journal-title":"Curr. Clin. Onco."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1124\/pr.56.4.3","volume":"56","author":"Hoeben A.","year":"2004","journal-title":"Pharmacol. Rev."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"7788","DOI":"10.1074\/jbc.271.13.7788","volume":"271","author":"Keyt B. A.","year":"1996","journal-title":"J. Biol. Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1042\/BST0371201","volume":"37","author":"Krilleke D.","year":"2009","journal-title":"Biochem. Soc. Trans."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"31508","DOI":"10.1074\/jbc.M414581200","volume":"280","author":"Ashikari-Hada S.","year":"2005","journal-title":"J. Biol. Chem."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"39748","DOI":"10.1074\/jbc.M101117200","volume":"276","author":"Hamma-Kourbali Y.","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S0969-2126(98)00065-3","volume":"15","author":"Fairbrother W. J.","year":"1998","journal-title":"Structure"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1023\/A:1015346504499","volume":"23","author":"Stauffer M. E.","year":"2002","journal-title":"J. Biomol. NMR"},{"key":"ref27\/cit27","unstructured":"Chae, C. B., Gho, Y. S., Yang, S., Bae, D. G., Kwon, B. O., and Hwang, S. (2010) Methods of Contacting \u03b2 amyloid protein with VEGF, U.S. Patent 7,795,213 B2."},{"key":"ref28\/cit28","first-page":"142","volume":"5","author":"Mukne A. P.","year":"2004","journal-title":"AAPS Pharm. Sci. Tech."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1126\/science.1066176","volume":"295","author":"Eisenmesser E. Z.","year":"2002","journal-title":"Science"},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"16046","DOI":"10.1021\/bi048119y","volume":"43","author":"Venkitakrishnan R. P.","year":"2004","journal-title":"Biochemistry"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"6072","DOI":"10.1021\/bi025655m","volume":"41","author":"Cole R.","year":"2002","journal-title":"Biochemistry"},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"15161","DOI":"10.1021\/bi026776p","volume":"41","author":"Codreanu S. G.","year":"2002","journal-title":"Biochemistry"},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"13588","DOI":"10.1074\/jbc.275.18.13588","volume":"275","author":"Bae D.-G.","year":"2000","journal-title":"J. Biol. Chem."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1158\/1078-0432.CCR-04-1564","volume":"11","author":"Bae D.-G.","year":"2005","journal-title":"Clin. Cancer Res."},{"issue":"3","key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1002\/pro.5560020312","volume":"2","author":"Levine H.","year":"1993","journal-title":"Protein Sci."},{"issue":"1","key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1099-1352(199601)9:1<1::AID-JMR241>3.0.CO;2-6","volume":"9","author":"Goodsell D. S.","year":"1996","journal-title":"J. Mol. Recognit."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1002\/(SICI)1096-987X(19981115)19:14<1639::AID-JCC10>3.0.CO;2-B","volume":"19","author":"Morris G. M.","year":"1998","journal-title":"J. Comput. Chem."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"6150","DOI":"10.1021\/bi00441a004","volume":"28","author":"Marion E.","year":"1989","journal-title":"Biochemistry"},{"key":"ref39\/cit39","first-page":"72","volume":"88","author":"Cavanagh J.","year":"1990","journal-title":"J. Magn. Reson."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"4856","DOI":"10.1021\/bi00135a017","volume":"31","author":"Kordel J.","year":"1992","journal-title":"Biochemistry"},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1006\/jmrb.1993.1095","volume":"102","author":"Skelton N. J.","year":"1993","journal-title":"J. Magn. Reson., Ser. B"},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"10663","DOI":"10.1021\/ja00052a088","volume":"114","author":"Kay L. E.","year":"1992","journal-title":"J. Am. Chem. Soc."},{"key":"ref43\/cit43","volume-title":"Protein NMR Techniques","author":"Kempf J. G.","year":"2003"},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF00197809","volume":"6","author":"Delaglio F.","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"ref45\/cit45","unstructured":"Goddard, T. D. and Kneller, D. G.SPARKY 3, University of California, San Francisco."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"4546","DOI":"10.1021\/ja00381a009","volume":"104","author":"Lipari G.","year":"1982","journal-title":"J. Am. Chem. Soc."},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"4559","DOI":"10.1021\/ja00381a010","volume":"104","author":"Lipari G.","year":"1982","journal-title":"J. Am. Chem. Soc."},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1023\/A:1023808801134","volume":"26","author":"Cole R.","year":"2003","journal-title":"J. Biomol. NMR"},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"4989","DOI":"10.1021\/ja00168a070","volume":"112","author":"Clore G. M.","year":"1990","journal-title":"J. Am. Chem. Soc."},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1021\/ja00012a001","volume":"113","author":"Palmer A. G.","year":"1991","journal-title":"J. Am. Chem. Soc."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1006\/jmbi.1994.0073","volume":"246","author":"Mandel A. M.","year":"1995","journal-title":"J. Mol. Biol."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"12562","DOI":"10.1021\/ja00155a020","volume":"117","author":"Tjandra N.","year":"1995","journal-title":"J. Am. Chem. Soc."},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"2378","DOI":"10.1021\/ja00216a006","volume":"110","author":"Hiyama Y.","year":"1988","journal-title":"J. Am. Chem. Soc."},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1006\/jmbi.1998.1837","volume":"279","author":"Fairbrother W. J.","year":"1998","journal-title":"J. Mol. Biol."},{"key":"ref55\/cit55","first-page":"381","volume":"62","author":"Lamy S.","year":"2002","journal-title":"Cancer Res."},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0304-3835(02)00007-1","volume":"180","author":"Kondo T.","year":"2002","journal-title":"Cancer Lett."},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/7573","volume":"6","author":"Pellecchia M.","year":"1999","journal-title":"Nat. Struct. Biol."},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"7192","DOI":"10.1073\/pnas.94.14.7192","volume":"94","author":"Muller Y. A.","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1006\/jmbi.1999.3134","volume":"293","author":"Starovasnik M. A.","year":"1999","journal-title":"J. Mol. Biol."},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"23779","DOI":"10.1074\/jbc.M110.130658","volume":"285","author":"Iyer S.","year":"2010","journal-title":"J. Biol. Chem."},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1016\/S0969-2126(98)00116-6","volume":"6","author":"Muller Y. A.","year":"1998","journal-title":"Structure"},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"17765","DOI":"10.1021\/bi9819327","volume":"37","author":"Wiesmann C.","year":"1998","journal-title":"Biochemistry"},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1006\/jmbi.1999.3192","volume":"293","author":"Chen Y.","year":"1999","journal-title":"J. Mol. Biol."},{"key":"ref64\/cit64","doi-asserted-by":"crossref","first-page":"4902","DOI":"10.1038\/sj.emboj.7601906","volume":"26","author":"Appleton B. A.","year":"2007","journal-title":"EMBO J."},{"key":"ref65\/cit65","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/j.jmb.2008.09.076","volume":"384","author":"Leonard P.","year":"2008","journal-title":"J. Mol. Biol."},{"key":"ref66\/cit66","doi-asserted-by":"crossref","first-page":"28045","DOI":"10.1074\/jbc.M700319200","volume":"282","author":"Krilleke D.","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"12","key":"ref67\/cit67","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.1016\/j.bpj.2010.03.047","volume":"98","author":"Long D.","year":"2010","journal-title":"Biopys. J."},{"issue":"11","key":"ref68\/cit68","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1038\/nchembio.238","volume":"5","author":"Baldwin A. J.","year":"2009","journal-title":"Nat. Chem. Biol."},{"issue":"2","key":"ref69\/cit69","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1021\/ar700132n","volume":"41","author":"Loria J. P.","year":"2008","journal-title":"Acc. Chem. Res."},{"key":"ref70\/cit70","doi-asserted-by":"crossref","first-page":"14324","DOI":"10.1021\/ja0367389","volume":"125","author":"Grey M. J.","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"ref71\/cit71","doi-asserted-by":"crossref","first-page":"39444","DOI":"10.1074\/jbc.M007205200","volume":"275","author":"Chi Y. H.","year":"2000","journal-title":"J. Biol. Chem."},{"key":"ref72\/cit72","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0263-7855(96)00009-4","volume":"14","author":"Koradi R.","year":"1996","journal-title":"J. Mol. Graphics"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi2000752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T04:12:04Z","timestamp":1680495124000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi2000752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,13]]},"references-count":72,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2011,6,7]]}},"alternative-id":["10.1021\/bi2000752"],"URL":"https:\/\/doi.org\/10.1021\/bi2000752","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,13]]}}}