{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:40:03Z","timestamp":1789533603292,"version":"build-2803163510"},"reference-count":48,"publisher":"American Chemical Society (ACS)","issue":"34","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2012,8,28]]},"DOI":"10.1021\/bi300656w","type":"journal-article","created":{"date-parts":[[2012,7,26]],"date-time":"2012-07-26T15:16:08Z","timestamp":1343315768000},"page":"6738-6752","source":"Crossref","is-referenced-by-count":23,"title":["Structural Insight into the Mechanism of DNA-Binding Attenuation of the Neisserial Adhesin Repressor NadR by the Small Natural Ligand 4-Hydroxyphenylacetic Acid"],"prefix":"10.1021","volume":"51","author":[{"given":"S\u00e9bastien","family":"Brier","sequence":"first","affiliation":[{"name":"Research\rCenter, Novartis Vaccines and Diagnostics, via Fiorentina 1, 53100, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Fagnocchi","sequence":"additional","affiliation":[{"name":"Research\rCenter, Novartis Vaccines and Diagnostics, via Fiorentina 1, 53100, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"Donnarumma","sequence":"additional","affiliation":[{"name":"Research\rCenter, Novartis Vaccines and Diagnostics, via Fiorentina 1, 53100, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Scarselli","sequence":"additional","affiliation":[{"name":"Research\rCenter, Novartis Vaccines and Diagnostics, via Fiorentina 1, 53100, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rino","family":"Rappuoli","sequence":"additional","affiliation":[{"name":"Research\rCenter, Novartis Vaccines and Diagnostics, via Fiorentina 1, 53100, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikkel","family":"Nissum","sequence":"additional","affiliation":[{"name":"Research\rCenter, Novartis Vaccines and Diagnostics, via Fiorentina 1, 53100, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Delany","sequence":"additional","affiliation":[{"name":"Research\rCenter, Novartis Vaccines and Diagnostics, via Fiorentina 1, 53100, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Norais","sequence":"additional","affiliation":[{"name":"Research\rCenter, Novartis Vaccines and Diagnostics, via Fiorentina 1, 53100, Siena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2012,8,15]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1017\/S0950268800066449","volume":"99","author":"Cartwright K. A.","year":"1987","journal-title":"Epidemiol. Infect."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1056\/NEJM200105033441807","volume":"344","author":"Rosenstein N. E.","year":"2001","journal-title":"N. Engl. J. Med."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1128\/JB.185.1.155-164.2003","volume":"185","author":"Dietrich G.","year":"2003","journal-title":"J. Bacteriol."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"e1002027","DOI":"10.1371\/journal.ppat.1002027","volume":"7","author":"Echenique-Rivera H.","year":"2011","journal-title":"PLoS Pathog."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.mib.2006.02.003","volume":"9","author":"Ellison D. W.","year":"2006","journal-title":"Curr. Opin. Microbiol."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/jmcb\/mjq021","volume":"2","author":"Perera I. C.","year":"2010","journal-title":"J. Mol. Cell. Biol."},{"key":"ref7\/cit7","first-page":"51","volume":"8","author":"Wilkinson S. P.","year":"2006","journal-title":"Curr. Issues Mol. Biol."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"e1000710","DOI":"10.1371\/journal.ppat.1000710","volume":"5","author":"Metruccio M. M.","year":"2009","journal-title":"PLoS Pathog."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1111\/j.1365-2958.2009.06710.x","volume":"72","author":"Schielke S.","year":"2009","journal-title":"Mol. Microbiol."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.1016\/j.vaccine.2009.02.098","volume":"27","author":"Bambini S.","year":"2009","journal-title":"Vaccine"},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"10834","DOI":"10.1073\/pnas.0603940103","volume":"103","author":"Giuliani M. M.","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1126\/science.287.5459.1816","volume":"287","author":"Pizza M.","year":"2000","journal-title":"Science"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"3770","DOI":"10.1073\/pnas.0915162107","volume":"107","author":"Serruto D.","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1128\/JB.06161-11","volume":"194","author":"Fagnocchi L.","year":"2012","journal-title":"J. Bacteriol."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.ijmm.2010.11.007","volume":"301","author":"Schielke S.","year":"2011","journal-title":"Int. J. Med. Microbiol."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1107\/S174430910900414X","volume":"65","author":"Nichols C. E.","year":"2009","journal-title":"Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"3530","DOI":"10.1128\/AEM.67.8.3530-3541.2001","volume":"67","author":"Providenti M. A.","year":"2001","journal-title":"Appl. Environ. Microbiol."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1038\/90429","volume":"8","author":"Alekshun M. N.","year":"2001","journal-title":"Nat. Struct. Biol."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"8617","DOI":"10.1073\/pnas.0913302107","volume":"107","author":"Chang Y. M.","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"22178","DOI":"10.1074\/jbc.M111.245258","volume":"286","author":"Dolan K. T.","year":"2011","journal-title":"J. Biol. Chem."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"4723","DOI":"10.1093\/nar\/gkp496","volume":"37","author":"Kumarevel T.","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.jmb.2008.01.001","volume":"377","author":"Saridakis V.","year":"2008","journal-title":"J. Mol. Biol."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/j.1600-0722.2009.00671.x","volume":"117","author":"Takahama U.","year":"2009","journal-title":"Eur. J. Oral Sci."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S0014-5793(02)02659-5","volume":"518","author":"Takahama U.","year":"2002","journal-title":"FEBS Lett."},{"key":"ref25\/cit25","volume-title":"Molecular Cloning: A Laboratory Manual","author":"Sambrook J.","year":"1989"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"3421","DOI":"10.1128\/JB.187.10.3421-3430.2005","volume":"187","author":"Ieva R.","year":"2005","journal-title":"J. Bacteriol."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ijms.2010.06.039","volume":"302","author":"Fang J.","year":"2011","journal-title":"Int. J. Mass Spectrom."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/j.jasms.2006.07.025","volume":"17","author":"Weis D. D.","year":"2006","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1002\/jcc.21256","volume":"30","author":"Morris G. M.","year":"2009","journal-title":"J. Comput. Chem."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.jmb.2006.05.005","volume":"360","author":"Bordelon T.","year":"2006","journal-title":"J. Mol. Biol."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.jmb.2009.03.030","volume":"388","author":"Di Fiore A.","year":"2009","journal-title":"J. Mol. Biol."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"29253","DOI":"10.1074\/jbc.M111381200","volume":"277","author":"Lim D.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.molcel.2007.09.016","volume":"28","author":"Newberry K. J.","year":"2007","journal-title":"Mol. Cell"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"23517","DOI":"10.1074\/jbc.M109.015826","volume":"284","author":"Poor C. B.","year":"2009","journal-title":"J. Biol. Chem."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"20240","DOI":"10.1074\/jbc.M300292200","volume":"278","author":"Wu R. Y.","year":"2003","journal-title":"J. Biol. Chem."},{"key":"ref36\/cit36","unstructured":"Lunin, V. V., Evdokimova, E., Kudritska, M., Cuff, M. E., Joachimiak, A., Edwards, A. M., and Savchenko, A.The crystal structure of transcriptional regulator PA4135, Unpublished work, PDB accession mumber2FBI."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/S0022-2836(02)00419-9","volume":"321","author":"Hamuro Y.","year":"2002","journal-title":"J. Mol. Biol."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1002\/mas.20064","volume":"25","author":"Wales T. E.","year":"2006","journal-title":"Mass Spectrom. Rev."},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.molcel.2005.09.013","volume":"20","author":"Hong M.","year":"2005","journal-title":"Mol. Cell"},{"key":"ref40\/cit40","unstructured":"Brzovic, P. S., Le Trong, I., Navarre, W. W., Fang, F. C., Stenkamp, R. E., and Libby, S. J.Crystal structure of transcription regulatory protein slyA fromSalmonella typhimuriumin complex with salicylate ligands. Unpublished work, PDB accession mumber3DEU."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0065-3233(08)60129-1","volume":"21","author":"Hvidt A.","year":"1966","journal-title":"Adv. Protein Chem."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/mas.10017","volume":"21","author":"Kaltashov I. A.","year":"2002","journal-title":"Mass Spectrom. Rev."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.jmb.2009.06.002","volume":"390","author":"Perera I. C.","year":"2009","journal-title":"J. Mol. Biol."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1021\/jf0108056","volume":"50","author":"Aura A. M.","year":"2002","journal-title":"J. Agric. Food Chem."},{"key":"ref45\/cit45","first-page":"711","volume":"5","author":"Gross M.","year":"1996","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1126\/science.287.5459.1809","volume":"287","author":"Tettelin H.","year":"2000","journal-title":"Science"},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/S0022-2836(83)80284-8","volume":"166","author":"Hanahan D.","year":"1983","journal-title":"J. Mol. Biol."},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/0022-2836(86)90385-2","volume":"189","author":"Studier F. W.","year":"1986","journal-title":"J. Mol. Biol."}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi300656w","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T07:26:35Z","timestamp":1681629995000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi300656w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,15]]},"references-count":48,"journal-issue":{"issue":"34","published-print":{"date-parts":[[2012,8,28]]}},"alternative-id":["10.1021\/bi300656w"],"URL":"https:\/\/doi.org\/10.1021\/bi300656w","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,15]]}}}