{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T17:18:34Z","timestamp":1792516714873,"version":"4.5.0"},"reference-count":221,"publisher":"American Chemical Society (ACS)","issue":"29","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2012,7,24]]},"DOI":"10.1021\/bi300752r","type":"journal-article","created":{"date-parts":[[2012,6,15]],"date-time":"2012-06-15T11:37:17Z","timestamp":1339760237000},"page":"5705-5724","source":"Crossref","is-referenced-by-count":560,"title":["Mechanisms of Mammalian Iron Homeostasis"],"prefix":"10.1021","volume":"51","author":[{"given":"Kostas","family":"Pantopoulos","sequence":"first","affiliation":[{"name":"Lady Davis Institute for Medical\rResearch, Jewish General Hospital and Department of Medicine, McGill University, Montreal, QC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suheel Kumar","family":"Porwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Tartakoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Devireddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2012,7,9]]},"reference":[{"key":"ref1\/cit1","unstructured":"Theil, E. C. and Raymond, K. N. (1994) inBioinorganic chemistry(Bertini, I., Gray, H. B., Lippard, S. J., and Valentine, J. S., Eds.) pp1\u201336,University Science Books,Mill Valley, CA."},{"key":"ref2\/cit2","unstructured":"Wigglesworth, J. M. and Baum, H. (1980) inIron in Biochemistry and Medicine(Jacobs, A. and Worwood, M., Eds.) Vol.II, pp29\u201386,Academic Press,New York."},{"key":"ref3\/cit3","unstructured":"Pereira, I. A. C., Teixeira, M., and Xavier, A. V. (2010) inBioinorganic chemistry: Trace element evolution from anaerobes to aerobes(Williams, R. J. P., Ed.) pp91\u2013190,Springer-Verlag,New York."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"26723","DOI":"10.1074\/jbc.270.45.26723","volume":"27","author":"Nielands J. B.","year":"1995","journal-title":"J. Biol. Chem."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1039\/b906679a","volume":"27","author":"Hider R. C.","year":"2010","journal-title":"Nat. Prod. Rep."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1042\/BJ20101825","volume":"434","author":"Wang J.","year":"2011","journal-title":"Biochem. J."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cell.2010.06.028","volume":"142","author":"Hentze M. W.","year":"2010","journal-title":"Cell"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/713609210","volume":"38","author":"Knutson M.","year":"2003","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1042\/BST0361239","volume":"36","author":"McKie A. T.","year":"2008","journal-title":"Biochem. Soc. Trans."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"4101","DOI":"10.3748\/wjg.14.4101","volume":"14","author":"West A. R.","year":"2008","journal-title":"World J. Gastroenterol."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1152\/physrev.00011.2005","volume":"86","author":"Ryter S. W.","year":"2006","journal-title":"Physiol. Rev."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.bbamcr.2011.02.007","volume":"1813","author":"Kovac S.","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.bbagen.2011.10.013","volume":"1820","author":"Gkouvatsos K.","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.bbagen.2011.07.014","volume":"1820","author":"Brissot P.","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0014-5793(00)01920-7","volume":"480","author":"Krause A.","year":"2000","journal-title":"FEBS Lett."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"7806","DOI":"10.1074\/jbc.M008922200","volume":"276","author":"Park C. H.","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1126\/science.1104742","volume":"306","author":"Nemeth E.","year":"2004","journal-title":"Science"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1091\/mbc.e07-01-0060","volume":"18","author":"De Domenico I.","year":"2007","journal-title":"Mol. Biol. Cell"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1053\/j.gastro.2010.12.037","volume":"140","author":"Brasse-Lagnel C.","year":"2011","journal-title":"Gastroenterology"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.bbagen.2008.08.006","volume":"1790","author":"Weiss G.","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/ng.130","volume":"40","author":"Finberg K. E.","year":"2008","journal-title":"Nat. Genet."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1146\/annurev-med-050109-142444","volume":"62","author":"Ganz T.","year":"2011","journal-title":"Annu. Rev. Med."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1039\/c1mt00082a","volume":"3","author":"Sebastiani G.","year":"2011","journal-title":"Metallomics"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/ng1053","volume":"33","author":"Roetto A.","year":"2003","journal-title":"Nat. Genet."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/ng1274","volume":"36","author":"Papanikolaou G.","year":"2004","journal-title":"Nat. Genet."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/ng0896-399","volume":"13","author":"Feder J. N.","year":"1996","journal-title":"Nat. Genet."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0140-6736(03)12602-5","volume":"361","author":"Bridle K. R.","year":"2003","journal-title":"Lancet"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/75534","volume":"25","author":"Camaschella C.","year":"2000","journal-title":"Nat. Genet."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"8955","DOI":"10.1073\/pnas.0503804102","volume":"102","author":"De Domenico I.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1053\/j.gastro.2011.02.064","volume":"140","author":"Mayr R.","year":"2011","journal-title":"Gastroenterology"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"4425","DOI":"10.1182\/blood-2011-01-258467","volume":"117","author":"Ganz T.","year":"2011","journal-title":"Blood"},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.bcmd.2007.07.009","volume":"40","author":"Valore E. V.","year":"2008","journal-title":"Blood Cells, Mol., Dis."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.1182\/blood-2009-01-201590","volume":"113","author":"Peslova G.","year":"2009","journal-title":"Blood"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"41163","DOI":"10.1074\/jbc.M202653200","volume":"277","author":"Courselaud B.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"4224","DOI":"10.1182\/blood-2011-03-339952","volume":"118","author":"Steinbicker A. U.","year":"2011","journal-title":"Blood"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"4096","DOI":"10.1182\/blood-2007-06-096503","volume":"110","author":"Piperno A.","year":"2007","journal-title":"Blood"},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"500","DOI":"10.3324\/haematol.2010.033449","volume":"96","author":"Girelli D.","year":"2011","journal-title":"Haematologica"},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1182\/blood-2002-11-3610","volume":"102","author":"Gehrke S. G.","year":"2003","journal-title":"Blood"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1136\/gut.2004.062018","volume":"54","author":"Wallace D. F.","year":"2005","journal-title":"Gut"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1172\/JCI25683","volume":"115","author":"Niederkofler V.","year":"2005","journal-title":"J. Clin. Invest."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1172\/JCI25049","volume":"115","author":"Huang F. W.","year":"2005","journal-title":"J. Clin. Invest."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1002\/hep.24178","volume":"53","author":"Ramos E.","year":"2011","journal-title":"Hepatology"},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1053\/j.gastro.2011.06.077","volume":"141","author":"Corradini E.","year":"2011","journal-title":"Gastroenterology"},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/ng1777","volume":"38","author":"Babitt J. L.","year":"2006","journal-title":"Nat. Genet."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s00109-009-0447-2","volume":"87","author":"Casanovasqq G.","year":"2009","journal-title":"J. Mol. Med."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.cmet.2005.10.010","volume":"2","author":"Wang R. H.","year":"2005","journal-title":"Cell Metab."},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1182\/blood-2009-09-238105","volume":"115","author":"Mleczko-Sanecka K.","year":"2010","journal-title":"Blood"},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1038\/ng.320","volume":"41","author":"Meynard D.","year":"2009","journal-title":"Nat. Genet."},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/ng.335","volume":"41","author":"Andriopoulos B.","year":"2009","journal-title":"Nat. Genet."},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1172\/JCI31342","volume":"117","author":"Babitt J. L.","year":"2007","journal-title":"J. Clin. Invest."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/nchembio.2007.54","volume":"4","author":"Yu P. B.","year":"2008","journal-title":"Nat. Chem. Biol."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"2884","DOI":"10.1182\/blood-2005-05-1845","volume":"106","author":"Lin L.","year":"2005","journal-title":"Blood"},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"6319","DOI":"10.1182\/blood-2010-12-327957","volume":"117","author":"Chen W.","year":"2011","journal-title":"Blood"},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1002\/hep.24547","volume":"54","author":"Gkouvatsos K.","year":"2011","journal-title":"Hepatology"},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.cmet.2008.09.012","volume":"8","author":"Silvestri L.","year":"2008","journal-title":"Cell Metab."},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1126\/science.1157121","volume":"320","author":"Du X.","year":"2008","journal-title":"Science"},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"2539","DOI":"10.1182\/blood-2008-04-149773","volume":"112","author":"Folgueras A. R.","year":"2008","journal-title":"Blood"},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.bcmd.2011.04.009","volume":"47","author":"Krijt J.","year":"2011","journal-title":"Blood Cells, Mol., Dis."},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1182\/blood-2011-04-348698","volume":"118","author":"Meynard D.","year":"2011","journal-title":"Blood"},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.cmet.2007.11.014","volume":"7","author":"Vujic Spasic M.","year":"2008","journal-title":"Cell Metab."},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1053\/j.gastro.2006.11.028","volume":"132","author":"Wallace D. F.","year":"2007","journal-title":"Gastroenterology"},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1111\/j.1365-2141.2008.07273.x","volume":"142","author":"van Dijk B. A.","year":"2008","journal-title":"Br. J. Haematol."},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.3945\/ajcn.2009.28129","volume":"90","author":"Zimmermann M. B.","year":"2009","journal-title":"Am. J. Clin. Nutr."},{"key":"ref64\/cit64","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0092-8674(00)81151-4","volume":"93","author":"Lebr\u00f3n J. A.","year":"1998","journal-title":"Cell"},{"key":"ref65\/cit65","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.cmet.2007.11.016","volume":"7","author":"Schmidt P. J.","year":"2008","journal-title":"Cell Metab."},{"key":"ref66\/cit66","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1006\/jmbi.2001.5048","volume":"313","author":"West A. P.","year":"2001","journal-title":"J. Mol. Biol."},{"key":"ref67\/cit67","doi-asserted-by":"crossref","first-page":"36862","DOI":"10.1074\/jbc.M706720200","volume":"282","author":"Chen J.","year":"2007","journal-title":"J. Biol. Chem."},{"key":"ref68\/cit68","doi-asserted-by":"crossref","first-page":"25866","DOI":"10.1074\/jbc.M401467200","volume":"279","author":"Giannetti A. M.","year":"2004","journal-title":"J. Biol. Chem."},{"key":"ref69\/cit69","doi-asserted-by":"crossref","first-page":"28494","DOI":"10.1074\/jbc.C600197200","volume":"281","author":"Goswami T.","year":"2006","journal-title":"J. Biol. Chem."},{"key":"ref70\/cit70","doi-asserted-by":"crossref","first-page":"4287","DOI":"10.1182\/blood-2004-06-2477","volume":"104","author":"Johnson M. B.","year":"2004","journal-title":"Blood"},{"key":"ref71\/cit71","doi-asserted-by":"crossref","first-page":"4294","DOI":"10.1182\/blood-2004-06-2481","volume":"104","author":"Robb A.","year":"2004","journal-title":"Blood"},{"key":"ref72\/cit72","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1053\/j.gastro.2010.06.013","volume":"139","author":"Pietrangelo A.","year":"2010","journal-title":"Gastroenterology"},{"key":"ref73\/cit73","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1002\/hep.23198","volume":"50","author":"Wallace D. F.","year":"2009","journal-title":"Hepatology"},{"key":"ref74\/cit74","doi-asserted-by":"crossref","first-page":"765","DOI":"10.3324\/haematol.2008.003541","volume":"94","author":"Ramey G.","year":"2009","journal-title":"Haematologica"},{"key":"ref75\/cit75","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.3324\/haematol.2010.027003","volume":"95","author":"Poli M.","year":"2010","journal-title":"Haematologica"},{"key":"ref76\/cit76","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1002\/hep.23814","volume":"52","author":"Ryan J. D.","year":"2010","journal-title":"Hepatology"},{"key":"ref77\/cit77","doi-asserted-by":"crossref","first-page":"3204","DOI":"10.1182\/blood-2006-06-027631","volume":"108","author":"Wrighting D. M.","year":"2006","journal-title":"Blood"},{"key":"ref78\/cit78","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1182\/blood-2006-07-033969","volume":"109","author":"Verga Falzacappa M. V.","year":"2007","journal-title":"Blood"},{"key":"ref79\/cit79","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1053\/j.gastro.2006.10.018","volume":"132","author":"Pietrangelo A.","year":"2007","journal-title":"Gastroenterology"},{"key":"ref80\/cit80","doi-asserted-by":"crossref","first-page":"3730","DOI":"10.1182\/blood-2006-06-028787","volume":"108","author":"Pak M.","year":"2006","journal-title":"Blood"},{"key":"ref81\/cit81","doi-asserted-by":"crossref","first-page":"667","DOI":"10.33549\/physiolres.930841","volume":"55","author":"Vokurka M.","year":"2006","journal-title":"Physiol. Res."},{"key":"ref82\/cit82","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1038\/nm1629","volume":"13","author":"Tanno T.","year":"2007","journal-title":"Nat. Med."},{"key":"ref83\/cit83","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1182\/blood-2008-12-195503","volume":"114","author":"Tanno T.","year":"2009","journal-title":"Blood"},{"key":"ref84\/cit84","doi-asserted-by":"crossref","first-page":"e23109","DOI":"10.1371\/journal.pone.0023109","volume":"6","author":"Santini V.","year":"2011","journal-title":"PLoS One"},{"key":"ref85\/cit85","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.1182\/blood-2004-12-4844","volume":"105","author":"Papanikolaou G.","year":"2005","journal-title":"Blood"},{"key":"ref86\/cit86","first-page":"809","volume":"91","author":"Kattamis A.","year":"2006","journal-title":"Haematologica"},{"key":"ref87\/cit87","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1172\/JCI31370","volume":"117","author":"Peyssonnaux C.","year":"2007","journal-title":"J. Clin. Invest."},{"key":"ref88\/cit88","doi-asserted-by":"crossref","first-page":"e7875","DOI":"10.1371\/journal.pone.0007875","volume":"4","author":"Volke M.","year":"2009","journal-title":"PLoS One"},{"key":"ref89\/cit89","doi-asserted-by":"crossref","first-page":"827","DOI":"10.3324\/haematol.2011.056119","volume":"97","author":"Mastrogiannaki M.","year":"2012","journal-title":"Haematologica"},{"key":"ref90\/cit90","doi-asserted-by":"crossref","first-page":"C888","DOI":"10.1152\/ajpcell.00121.2010","volume":"300","author":"Chaston T. B.","year":"2011","journal-title":"Am. J. Physiol."},{"key":"ref91\/cit91","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.cmet.2008.12.012","volume":"9","author":"Shah Y. M.","year":"2009","journal-title":"Cell Metab."},{"key":"ref92\/cit92","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1172\/JCI38499","volume":"119","author":"Mastrogiannaki M.","year":"2009","journal-title":"J. Clin. Invest."},{"key":"ref93\/cit93","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.cmet.2010.08.003","volume":"12","author":"Vanoaica L.","year":"2010","journal-title":"Cell Metab."},{"key":"ref94\/cit94","doi-asserted-by":"crossref","first-page":"4148","DOI":"10.1182\/blood-2002-08-2459","volume":"101","author":"Ludwiczek S.","year":"2003","journal-title":"Blood"},{"key":"ref95\/cit95","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/jcp.20932","volume":"211","author":"Paradkar P. N.","year":"2007","journal-title":"J. Cell. Physiol."},{"key":"ref96\/cit96","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0014-5793(01)03189-1","volume":"509","author":"Gunshin H.","year":"2001","journal-title":"FEBS Lett."},{"key":"ref97\/cit97","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/S0168-8278(03)00408-2","volume":"39","author":"Lymboussaki A.","year":"2003","journal-title":"J. Hepatol."},{"key":"ref98\/cit98","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1053\/j.gastro.2004.11.057","volume":"128","author":"Pietrangelo A.","year":"2005","journal-title":"Gastroenterology"},{"key":"ref99\/cit99","first-page":"585","volume":"35","author":"Aisen P.","year":"1998","journal-title":"Met. Ions Biol. Syst."},{"key":"ref100\/cit100","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/35042073","volume":"1","author":"Andrews N. C.","year":"2000","journal-title":"Nat. Rev. Genet."},{"key":"ref101\/cit101","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.biocel.2004.02.007","volume":"36","author":"Aisen P.","year":"2004","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"ref102\/cit102","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1073\/pnas.80.8.2258","volume":"80","author":"Dautry-Varsat A.","year":"1983","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref103\/cit103","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1021\/bi00216a003","volume":"30","author":"Bali P. K.","year":"1991","journal-title":"Biochemistry"},{"key":"ref104\/cit104","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1182\/blood-2006-02-003681","volume":"108","author":"Ohgami R. S.","year":"2006","journal-title":"Blood"},{"key":"ref105\/cit105","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/ng0897-383","volume":"16","author":"Fleming M. D.","year":"1997","journal-title":"Nat. Genet."},{"key":"ref106\/cit106","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1073\/pnas.95.3.1148","volume":"95","author":"Fleming M. D.","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref107\/cit107","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/41343","volume":"388","author":"Gunshin H.","year":"1997","journal-title":"Nature"},{"key":"ref108\/cit108","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1172\/JCI24356","volume":"115","author":"Gunshin H.","year":"2005","journal-title":"J. Clin. Invest."},{"key":"ref109\/cit109","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1182\/blood-2004-07-2966","volume":"105","author":"Mims M. P.","year":"2005","journal-title":"Blood"},{"key":"ref110\/cit110","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1038\/ng1658","volume":"37","author":"Ohgami R. S.","year":"2005","journal-title":"Nat. Genet."},{"key":"ref111\/cit111","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1182\/blood-2005-01-0379","volume":"106","author":"Ohgami R. S.","year":"2005","journal-title":"Blood"},{"key":"ref112\/cit112","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1182\/blood-2007-11-120402","volume":"113","author":"Lambe T.","year":"2009","journal-title":"Blood"},{"key":"ref113\/cit113","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1038\/7727","volume":"21","author":"Levy J. E.","year":"1999","journal-title":"Nat. Genet."},{"key":"ref114\/cit114","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1056\/NEJM198407263110402","volume":"311","author":"Larrick J.","year":"1984","journal-title":"N. Engl. J. Med."},{"key":"ref115\/cit115","doi-asserted-by":"crossref","first-page":"20826","DOI":"10.1074\/jbc.274.30.20826","volume":"274","author":"Kawabata H.","year":"1999","journal-title":"J. Biol. Chem."},{"key":"ref116\/cit116","doi-asserted-by":"crossref","first-page":"38135","DOI":"10.1074\/jbc.C000664200","volume":"275","author":"West A. P.","year":"2000","journal-title":"J. Biol. Chem."},{"key":"ref117\/cit117","doi-asserted-by":"crossref","first-page":"4287","DOI":"10.1182\/blood-2004-06-2477","volume":"104","author":"Johnson M. B.","year":"2004","journal-title":"Blood"},{"key":"ref118\/cit118","doi-asserted-by":"crossref","first-page":"4294","DOI":"10.1182\/blood-2004-06-2481","volume":"104","author":"Robb A.","year":"2004","journal-title":"Blood"},{"key":"ref119\/cit119","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1182\/blood-2004-04-1416","volume":"105","author":"Kawabata H.","year":"2005","journal-title":"Blood"},{"key":"ref120\/cit120","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1053\/j.gastro.2006.11.028","volume":"132","author":"Wallace D. F.","year":"2007","journal-title":"Gastroenterology"},{"key":"ref121\/cit121","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0955-3886(00)00087-4","volume":"23","author":"Breuer W.","year":"2000","journal-title":"Transfus. Sci."},{"key":"ref122\/cit122","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/S1097-2765(02)00710-4","volume":"10","author":"Yang J.","year":"2002","journal-title":"Mol. Cell"},{"key":"ref123\/cit123","first-page":"F9","volume":"285","author":"Yang J.","year":"2003","journal-title":"Am. J. Physiol."},{"key":"ref124\/cit124","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/nature03104","volume":"432","author":"Flo T. H.","year":"2004","journal-title":"Nature"},{"key":"ref125\/cit125","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1073\/pnas.0510847103","volume":"103","author":"Berger T.","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref126\/cit126","doi-asserted-by":"crossref","first-page":"20606","DOI":"10.1074\/jbc.M110.216549","volume":"286","author":"Liu Z.","year":"2011","journal-title":"J. Biol. Chem."},{"key":"ref127\/cit127","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1002\/hep.22699","volume":"49","author":"Huang H.","year":"2009","journal-title":"Hepatology"},{"key":"ref128\/cit128","first-page":"G964","volume":"288","author":"Collins J. F.","year":"2005","journal-title":"Am. J. Physiol."},{"key":"ref129\/cit129","first-page":"152","volume":"35","author":"Shindo M.","year":"2006","journal-title":"Hepatol. Res."},{"key":"ref130\/cit130","doi-asserted-by":"crossref","first-page":"0378","DOI":"10.1371\/journal.pbio.0020378","volume":"2","author":"Xu H.","year":"2004","journal-title":"PLoS Biol."},{"key":"ref131\/cit131","doi-asserted-by":"crossref","first-page":"13612","DOI":"10.1073\/pnas.0606424103","volume":"103","author":"Liuzzi J. P.","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref132\/cit132","doi-asserted-by":"crossref","first-page":"21462","DOI":"10.1074\/jbc.M803150200","volume":"283","author":"Gao J.","year":"2008","journal-title":"J. Biol. Chem."},{"key":"ref133\/cit133","doi-asserted-by":"crossref","first-page":"e18059","DOI":"10.1371\/journal.pone.0018059","volume":"6","author":"Hojyo S.","year":"2011","journal-title":"PLoS One"},{"key":"ref134\/cit134","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1161\/01.RES.84.11.1302","volume":"84","author":"Tsushima R. G.","year":"1999","journal-title":"Circ. Res."},{"key":"ref135\/cit135","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1038\/nm920","volume":"9","author":"Oudit G. Y.","year":"2003","journal-title":"Nat. Med."},{"key":"ref136\/cit136","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/nm1542","volume":"13","author":"Ludwiczek S.","year":"2007","journal-title":"Nat. Med."},{"key":"ref137\/cit137","doi-asserted-by":"crossref","first-page":"4148","DOI":"10.1182\/blood-2010-03-274738","volume":"115","author":"Mackenzie B.","year":"2010","journal-title":"Blood"},{"key":"ref138\/cit138","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.pharmthera.2004.12.003","volume":"106","author":"Moosmang M.","year":"2005","journal-title":"Pharmacol. Ther."},{"key":"ref139\/cit139","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1084\/jem.20042433","volume":"202","author":"Chen T. T.","year":"2005","journal-title":"J. Exp. Med."},{"key":"ref140\/cit140","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.devcel.2008.12.002","volume":"16","author":"Li J. Y.","year":"2009","journal-title":"Dev. Cell"},{"key":"ref141\/cit141","doi-asserted-by":"crossref","first-page":"4311","DOI":"10.4049\/jimmunol.177.7.4311","volume":"177","author":"Rennert P. D.","year":"2006","journal-title":"J. Immunol."},{"key":"ref142\/cit142","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1172\/JCI38012","volume":"120","author":"Huang J.","year":"2010","journal-title":"J. Clin. Invest."},{"key":"ref143\/cit143","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.cell.2005.06.025","volume":"122","author":"Shayegi M.","year":"2005","journal-title":"Cell"},{"key":"ref144\/cit144","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.cell.2006.09.041","volume":"127","author":"Qiu A. D.","year":"2006","journal-title":"Cell"},{"key":"ref145\/cit145","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1080\/10245330500093419","volume":"10","author":"Mims M. P.","year":"2005","journal-title":"Hematology"},{"key":"ref146\/cit146","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1038\/nature07311","volume":"455","author":"Dong X.-P.","year":"2008","journal-title":"Nature"},{"key":"ref147\/cit147","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1038\/nature06934","volume":"453","author":"Rajagopal A.","year":"2008","journal-title":"Nature"},{"key":"ref148\/cit148","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.mrfmmm.2003.08.004","volume":"531","author":"Kruszewski M.","year":"2003","journal-title":"Mutat. Res."},{"key":"ref149\/cit149","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1515\/BC.2002.051","volume":"383","author":"Petrat F.","year":"2002","journal-title":"Biol. Chem."},{"key":"ref150\/cit150","doi-asserted-by":"crossref","first-page":"3242","DOI":"10.1182\/blood-2005-02-0460","volume":"106","author":"Glickstein H.","year":"2005","journal-title":"Blood"},{"key":"ref151\/cit151","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/S0891-5849(97)00016-6","volume":"23","author":"Meneghini R.","year":"1997","journal-title":"Free Radical Biol. Med."},{"key":"ref152\/cit152","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/j.cell.2005.10.027","volume":"123","author":"Devireddy L. R.","year":"2005","journal-title":"Cell"},{"key":"ref153\/cit153","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/j.cell.2005.12.008","volume":"123","author":"Richardson D. R.","year":"2005","journal-title":"Cell"},{"key":"ref154\/cit154","doi-asserted-by":"crossref","first-page":"10775","DOI":"10.1073\/pnas.0912925107","volume":"107","author":"Richardson D. R.","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref155\/cit155","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0092-8674(78)90235-0","volume":"14","author":"Fernandez-Pol J. A.","year":"1977","journal-title":"Cell"},{"key":"ref156\/cit156","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1084\/jem.151.2.418","volume":"151","author":"Jones R.","year":"1980","journal-title":"J. Exp. Med."},{"key":"ref157\/cit157","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0167-4838(00)00169-2","volume":"1482","author":"Flower D. R.","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"ref158\/cit158","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S1097-2765(02)00708-6","volume":"10","author":"Goetz D.","year":"2002","journal-title":"Mol. Cell"},{"key":"ref159\/cit159","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/nchembio771","volume":"2","author":"Fischbach M. A.","year":"2006","journal-title":"Nat. Chem. Biol."},{"key":"ref160\/cit160","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.cell.2010.04.040","volume":"141","author":"Devireddy L. R.","year":"2010","journal-title":"Cell"},{"key":"ref161\/cit161","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1128\/MMBR.66.2.223-249.2002","volume":"66","author":"Crosa J. H.","year":"2002","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"ref162\/cit162","doi-asserted-by":"crossref","first-page":"3584","DOI":"10.1073\/pnas.0630018100","volume":"100","author":"Raymond K. N.","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref163\/cit163","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.cmet.2010.08.001","volume":"12","author":"Muhlenhoff U.","year":"2010","journal-title":"Cell Metab."},{"key":"ref164\/cit164","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.cmet.2009.06.012","volume":"10","author":"Nilsson R.","year":"2009","journal-title":"Cell Metab."},{"key":"ref165\/cit165","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/nature04512","volume":"440","author":"Shaw G. C.","year":"2006","journal-title":"Nature"},{"key":"ref166\/cit166","doi-asserted-by":"crossref","first-page":"16263","DOI":"10.1073\/pnas.0904519106","volume":"106","author":"Chen W.","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref167\/cit167","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1128\/MCB.01685-08","volume":"29","author":"Paradkar P. N.","year":"2009","journal-title":"Mol. Cell. Biol."},{"key":"ref168\/cit168","doi-asserted-by":"crossref","first-page":"5494","DOI":"10.1182\/blood-2010-11-319483","volume":"117","author":"Troadec M.-B.","year":"2011","journal-title":"Blood"},{"key":"ref169\/cit169","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1182\/blood-2004-06-2226","volume":"105","author":"Zhang A. S.","year":"2005","journal-title":"Blood"},{"key":"ref170\/cit170","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.cmet.2010.06.007","volume":"12","author":"Galy B.","year":"2010","journal-title":"Cell Metab."},{"key":"ref171\/cit171","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.bbamcr.2006.05.005","volume":"1763","author":"Ajioka R. S.","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"ref172\/cit172","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1159\/000243796","volume":"122","author":"Sheftel A. D.","year":"2009","journal-title":"Acta Hematol."},{"key":"ref173\/cit173","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1038\/nature05125","volume":"443","author":"Krishnamurthy P. C.","year":"2006","journal-title":"Nature"},{"key":"ref174\/cit174","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1093\/clinchem\/47.6.1112","volume":"47","author":"Rufenacht U.","year":"2001","journal-title":"Clin. Chem."},{"key":"ref175\/cit175","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.cmet.2006.02.003","volume":"3","author":"Tong W. H.","year":"2006","journal-title":"Cell Metab."},{"key":"ref176\/cit176","doi-asserted-by":"crossref","first-page":"26737","DOI":"10.1074\/jbc.R110.118679","volume":"285","author":"Stemmler T. L.","year":"2010","journal-title":"J. Biol. Chem."},{"key":"ref177\/cit177","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/s00415-009-1004-1","volume":"256","author":"Puccio H.","year":"2009","journal-title":"J. Neurol."},{"key":"ref178\/cit178","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1146\/annurev.biochem.76.052705.162653","volume":"77","author":"Lill R.","year":"2008","journal-title":"Annu. Rev. Biochem."},{"key":"ref179\/cit179","doi-asserted-by":"crossref","first-page":"3981","DOI":"10.1093\/emboj\/18.14.3981","volume":"18","author":"Kispal G.","year":"1999","journal-title":"EMBO J."},{"key":"ref180\/cit180","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/hmg\/ddl012","volume":"15","author":"Pondarre C.","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"ref181\/cit181","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1182\/blood-2004-10-3856","volume":"105","author":"Napier I.","year":"2005","journal-title":"Blood"},{"key":"ref182\/cit182","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1093\/hmg\/8.5.743","volume":"8","author":"Allikmets R.","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"ref183\/cit183","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1261\/rna.464807","volume":"13","author":"Piccinelli P.","year":"2007","journal-title":"RNA"},{"key":"ref184\/cit184","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1006\/bcmd.2002.0590","volume":"29","author":"Roetto A.","year":"2002","journal-title":"Blood Cells, Mol., Dis."},{"key":"ref185\/cit185","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.bbagen.2010.02.005","volume":"1800","author":"Arosio P.","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"ref186\/cit186","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.cmet.2009.03.006","volume":"9","author":"Zhang D. L.","year":"2009","journal-title":"Cell Metab."},{"key":"ref187\/cit187","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S1097-2765(00)80425-6","volume":"5","author":"McKie A. T.","year":"2000","journal-title":"Mol. Cell"},{"key":"ref188\/cit188","doi-asserted-by":"crossref","first-page":"4159","DOI":"10.1182\/blood-2005-05-1809","volume":"107","author":"Schranzhofer M.","year":"2006","journal-title":"Blood"},{"key":"ref189\/cit189","doi-asserted-by":"crossref","first-page":"24185","DOI":"10.1074\/jbc.M000944200","volume":"275","author":"Lok C. N.","year":"2000","journal-title":"J. Biol. Chem."},{"key":"ref190\/cit190","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1126\/science.1176333","volume":"326","author":"Vashisht A. A.","year":"2009","journal-title":"Science"},{"key":"ref191\/cit191","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1126\/science.1176326","volume":"326","author":"Salahudeen A. A.","year":"2009","journal-title":"Science"},{"key":"ref192\/cit192","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/sj.emboj.7600954","volume":"25","author":"Clarke S. L.","year":"2006","journal-title":"EMBO J."},{"key":"ref193\/cit193","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1128\/MCB.01111-06","volume":"27","author":"Wang J.","year":"2007","journal-title":"Mol. Cell. Biol."},{"key":"ref194\/cit194","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.bcmd.2005.12.006","volume":"36","author":"Smith S. R.","year":"2006","journal-title":"Blood Cells, Mol., Dis."},{"key":"ref195\/cit195","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.cmet.2007.10.006","volume":"7","author":"Galy B.","year":"2008","journal-title":"Cell Metab."},{"key":"ref196\/cit196","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/sj.emboj.7600041","volume":"23","author":"Meyron-Holtz E. G.","year":"2004","journal-title":"EMBO J."},{"key":"ref197\/cit197","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1182\/blood-2004-12-4703","volume":"106","author":"Cooperman S. S.","year":"2005","journal-title":"Blood"},{"key":"ref198\/cit198","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1182\/blood-2005-04-1365","volume":"106","author":"Galy B.","year":"2005","journal-title":"Blood"},{"key":"ref199\/cit199","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1182\/blood-2008-05-155093","volume":"113","author":"Ferring-Appel D.","year":"2009","journal-title":"Blood"},{"key":"ref200\/cit200","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1038\/84859","volume":"27","author":"LaVaute T.","year":"2001","journal-title":"Nat. Genet."},{"key":"ref201\/cit201","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.cmet.2011.07.011","volume":"14","author":"Moroishi T.","year":"2011","journal-title":"Cell Metab."},{"key":"ref202\/cit202","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.bbagen.2008.09.004","volume":"1790","author":"Arosio P.","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"ref203\/cit203","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1126\/science.1157643","volume":"320","author":"Shi H.","year":"2009","journal-title":"Science"},{"key":"ref204\/cit204","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1089\/ars.2010.3129","volume":"13","author":"Zhang Y.","year":"2010","journal-title":"Antioxid. Redox Signaling"},{"key":"ref205\/cit205","doi-asserted-by":"crossref","first-page":"5396","DOI":"10.1038\/sj.emboj.7601409","volume":"25","author":"De Domenico I.","year":"2006","journal-title":"EMBO J."},{"key":"ref206\/cit206","doi-asserted-by":"crossref","first-page":"4546","DOI":"10.1182\/blood-2009-05-224188","volume":"114","author":"De Domenico I.","year":"2009","journal-title":"Blood"},{"key":"ref207\/cit207","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1182\/blood-2003-06-1842","volume":"103","author":"Cozzi A.","year":"2004","journal-title":"Blood"},{"key":"ref208\/cit208","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1182\/blood.V94.10.3593.422k26_3593_3603","volume":"94","author":"Epsztein S.","year":"1999","journal-title":"Blood"},{"key":"ref209\/cit209","doi-asserted-by":"crossref","first-page":"24437","DOI":"10.1074\/jbc.C100141200","volume":"276","author":"Levi S.","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref210\/cit210","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1369\/jhc.7A7273.2007","volume":"55","author":"Santambrogio P.","year":"2007","journal-title":"J. Histochem. Cytochem."},{"key":"ref211\/cit211","doi-asserted-by":"crossref","first-page":"2428","DOI":"10.1182\/blood-2006-04-018341","volume":"108","author":"Nie G.","year":"2006","journal-title":"Blood"},{"key":"ref212\/cit212","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.cmet.2005.02.005","volume":"1","author":"Ganz T.","year":"2005","journal-title":"Cell Metab."},{"key":"ref213\/cit213","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/nrm2295","volume":"9","author":"De Domenico I.","year":"2008","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"ref214\/cit214","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.cmet.2005.01.003","volume":"1","author":"Donovan A.","year":"2005","journal-title":"Cell Metab."},{"key":"ref215\/cit215","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1172\/JCI200113468","volume":"108","author":"Montosi G.","year":"2002","journal-title":"J. Clin. Invest."},{"key":"ref216\/cit216","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1126\/science.1151133","volume":"319","author":"Keel S. B.","year":"2008","journal-title":"Science"},{"key":"ref217\/cit217","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.cell.2004.08.014","volume":"118","author":"Quigley J. G.","year":"2004","journal-title":"Cell"},{"key":"ref218\/cit218","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/j.ajhg.2010.10.013","volume":"87","author":"Rajadhyaksha A. M.","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"ref219\/cit219","doi-asserted-by":"crossref","first-page":"5318","DOI":"10.1128\/MCB.00690-10","volume":"30","author":"Duffy S. P.","year":"2010","journal-title":"Mol. Cell. Biol."},{"key":"ref220\/cit220","doi-asserted-by":"crossref","first-page":"15649","DOI":"10.1073\/pnas.202607599","volume":"99","author":"Jonker J. W.","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref221\/cit221","doi-asserted-by":"crossref","first-page":"10338","DOI":"10.1073\/pnas.0901249106","volume":"106","author":"Woodward O. M.","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi300752r","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T05:37:12Z","timestamp":1680500232000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi300752r"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7,9]]},"references-count":221,"journal-issue":{"issue":"29","published-print":{"date-parts":[[2012,7,24]]}},"alternative-id":["10.1021\/bi300752r"],"URL":"https:\/\/doi.org\/10.1021\/bi300752r","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7,9]]}}}