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Lipid Res."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"7341","DOI":"10.1021\/bi200574f","volume":"50","author":"McCauliff L. A.","year":"2011","journal-title":"Biochemistry"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"5477","DOI":"10.1073\/pnas.0914309107","volume":"107","author":"Rosenbaum A. I.","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"e6951","DOI":"10.1371\/journal.pone.0006951","volume":"4","author":"Davidson C. D.","year":"2009","journal-title":"PLoS ONE"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1002\/jbm.a.10444","volume":"65","author":"Li J.","year":"2003","journal-title":"J. Biomed. Mater. Res. A"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"4132","DOI":"10.1016\/j.biomaterials.2006.03.025","volume":"27","author":"Li J.","year":"2006","journal-title":"Biomaterials"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1021\/bc970189c","volume":"9","author":"Yui N.","year":"1998","journal-title":"Bioconjugate Chem."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"13016","DOI":"10.1021\/ja034583z","volume":"125","author":"Ooya T.","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1021\/ja046294w","volume":"127","author":"Liu Y.","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1021\/bm0602076","volume":"7","author":"Loethen S.","year":"2006","journal-title":"Biomacromolecules"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1002\/marc.1995.030160405","volume":"16","author":"Ooya T.","year":"1995","journal-title":"Macromol. Rapid Commun."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1163\/156856297X00371","volume":"8","author":"Ooya T.","year":"1997","journal-title":"J. Biomater. Sci., Polym. Ed."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"7115","DOI":"10.1021\/ma970680z","volume":"30","author":"Harada A.","year":"1997","journal-title":"Macromolecules"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1002\/pol.1976.130140803","volume":"14","author":"Ogata N.","year":"1976","journal-title":"J. Polym. Sci,. Polym. Lett. Ed"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1039\/c39900001322","volume":"19","author":"Harada A.","year":"1990","journal-title":"J. Chem. Soc., Chem. Commun."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/356325a0","volume":"356","author":"Harada A.","year":"1992","journal-title":"Nature"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1038\/370126a0","volume":"370","author":"Harada A.","year":"1994","journal-title":"Nature"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"8406","DOI":"10.1021\/ma00128a060","volume":"28","author":"Harada A.","year":"1995","journal-title":"Macromolecules"},{"key":"ref29\/cit29","first-page":"61","volume":"347","author":"Panova I. G.","year":"1996","journal-title":"Dokl. Akad. Nauk"},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0169-409X(02)00018-2","volume":"54","author":"Kabanov A. V.","year":"2002","journal-title":"Adv. Drug Delivery Rev."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1002\/jssc.200600199","volume":"29","author":"Hemstrom P.","year":"2006","journal-title":"J. Sep. Sci."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.jpba.2005.04.034","volume":"39","author":"Agueros M.","year":"2005","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1007\/s00216-010-4187-5","volume":"399","author":"Beirne J.","year":"2011","journal-title":"Anal. Bioanal. Chem."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.ab.2003.12.014","volume":"326","author":"Vistica J.","year":"2004","journal-title":"Anal. Biochem."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1016\/S0006-3495(00)76713-0","volume":"78","author":"Schuck P.","year":"2000","journal-title":"Biophys. J."},{"key":"ref36\/cit36","unstructured":"Laue, T. M., Shah, B. D., Ridgeway, T. M., and Pelletier, S. L.Analytical Ultracentrifugation in Biochemistry and Polymer Science,Harding, S. and Rowe, A., Eds.Royal Society of Chemistry: 1992, pp.90\u2013125."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"6167","DOI":"10.1002\/chem.200305245","volume":"9","author":"Michels J.","year":"2003","journal-title":"Chem.\u2014Eur. J."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/3-540-44672-9_4","volume":"119","author":"Tziatzios C.","year":"2002","journal-title":"Prog. Colloid Polym. Sci."},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1063\/1.1673336","volume":"52","author":"Tanner J. E.","year":"1970","journal-title":"J. Chem. Phys."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"9859","DOI":"10.1021\/ma035513f","volume":"36","author":"Zhao T.","year":"2003","journal-title":"Macromolecules"},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.jcis.2010.07.019","volume":"350","author":"Qin J.","year":"2010","journal-title":"J. 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