{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:02:51Z","timestamp":1762542171075},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2013,5,28]]},"DOI":"10.1021\/bi4003887","type":"journal-article","created":{"date-parts":[[2013,5,16]],"date-time":"2013-05-16T18:05:09Z","timestamp":1368727509000},"page":"3712-3720","source":"Crossref","is-referenced-by-count":10,"title":["Covalent Inhibition of Serine \u03b2-Lactamases by Novel Hydroxamic Acid Derivatives"],"prefix":"10.1021","volume":"52","author":[{"given":"Ronak","family":"Tilvawala","sequence":"first","affiliation":[{"name":"Department of Chemistry, Wesleyan University, Lawn Avenue, Middletown, Connecticut\r06459, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. F.","family":"Pratt","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Wesleyan University, Lawn Avenue, Middletown, Connecticut\r06459, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2013,5,16]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1093\/jac\/dkq217","volume":"65","author":"Sykes R.","year":"2010","journal-title":"J. Antimicrob. Chemother."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"3013","DOI":"10.1021\/jm9012938","volume":"53","author":"Oelschlaeger P.","year":"2010","journal-title":"J. Med. Chem."},{"key":"ref3\/cit3","first-page":"343","volume-title":"Bacterial resistance to antimicrobials","author":"Georgopapadakou N. H.","year":"2008","edition":"2"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1586\/17512433.1.4.559","volume":"1","author":"Helfand M. S.","year":"2008","journal-title":"Expert Rev. Clin. Pharmacol."},{"key":"ref5\/cit5","volume-title":"\u03b2-Lactamases","author":"Wouters J.","year":"2012"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1128\/CMR.00037-09","volume":"23","author":"Drawz S. M.","year":"2010","journal-title":"Clin. Microbiol. Rev."},{"key":"ref7\/cit7","volume-title":"The Chemistry of \u03b2-Lactams","author":"Pratt R. F.","year":"1992"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1128\/AAC.00693-09","volume":"54","author":"Papp-Wallace K. M.","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"6420","DOI":"10.1016\/j.tet.2011.03.117","volume":"67","author":"Omura S.","year":"2011","journal-title":"Tetrahedron"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"949","DOI":"10.4155\/fmc.10.21","volume":"2","author":"Johnson D. S.","year":"2010","journal-title":"Future Med. Chem."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nrd3410","volume":"10","author":"Singh J.","year":"2011","journal-title":"Nat. Rev. Drug Discovery"},{"key":"ref12\/cit12","volume-title":"\u03b2-Lactamases","author":"Pratt R. F.","year":"2012"},{"key":"ref13\/cit13","volume-title":"\u03b2-Lactamases","author":"Buynak J. D.","year":"2012"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.cbpa.2010.03.035","volume":"14","author":"Kluge A. F.","year":"2010","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"9548","DOI":"10.1021\/ja072370u","volume":"129","author":"Wyrembak P. N.","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"12037","DOI":"10.1021\/bi8015247","volume":"47","author":"Pelto R. B.","year":"2008","journal-title":"Biochemistry"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"2946","DOI":"10.1021\/jo00114a059","volume":"60","author":"Saady M.","year":"1995","journal-title":"J. Org. Chem."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1006\/abio.1996.0238","volume":"237","author":"Kuzmic P.","year":"1996","journal-title":"Anal. Biochem."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"14988","DOI":"10.1021\/jp060168s","volume":"110","author":"Borden J.","year":"2006","journal-title":"J. Phys. Chem. B"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"5300","DOI":"10.1016\/j.tetlet.2008.06.083","volume":"49","author":"Dueymes C.","year":"2008","journal-title":"Tetrahedron Lett."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/1099-0690(200101)2001:1<141::AID-EJOC141>3.0.CO;2-J","author":"Cabaret D.","year":"2001","journal-title":"Eur. J. Org. Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1021\/bi00833a028","volume":"8","author":"De Jersey J.","year":"1969","journal-title":"Biochemistry"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1039\/p29910000947","author":"Rahil J.","year":"1991","journal-title":"J. Chem. Soc., Perkin Trans. 2"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1039\/p29800000181","author":"Farrar C. R.","year":"1980","journal-title":"J. Chem. Soc., Perkin Trans. 2"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1021\/jo00055a031","volume":"58","author":"Pfeiffer M. J.","year":"1993","journal-title":"J. Org. Chem."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"4186","DOI":"10.1016\/j.febslet.2012.10.019","volume":"586","author":"Adediran S. A.","year":"2012","journal-title":"FEBS Lett."},{"key":"ref27\/cit27","unstructured":"Jencks, W. P. and Regenstein, J. (1975) inHandbook of Biochemistry and Molecular Biology(Fasman, G. D., Ed.)3rd ed., Physical and Chemical Data, Vol.1, pp305\u2013351,CRC Press,Cleveland, OH."},{"key":"ref28\/cit28","unstructured":"Calculated using Advanced Chemistry Development (ACD\/Labs) version 11.02 (1994\u20132013) ."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1039\/jr9600001859","author":"Hudson R. F.","year":"1960","journal-title":"J. Chem. Soc."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1021\/jo00800a021","volume":"36","author":"Hays H. R.","year":"1971","journal-title":"J. Org. Chem."},{"key":"ref31\/cit31","unstructured":"Di Ninno, F., Hammond, M. L., Dykstra, K., Kim, S., Tan, Q., Young, K., Hermes, J. D., Chen, H., Raeppel, S., and Mannion, M. (2008) (Hetero)arylsulfonamidomethylphosphonate derivatives as \u03b2-lactamase inhibitors and their preparation, pharmaceutical compositions and use in the treatment of bacterial infection. PCT Int. Appl. WO 2008073142."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"5869","DOI":"10.1021\/bi00140a024","volume":"31","author":"Rahil J.","year":"1992","journal-title":"Biochemistry"},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"3252","DOI":"10.1021\/cr050287o","volume":"106","author":"Cleland W. W.","year":"2006","journal-title":"Chem. Rev."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1042\/bj2750793","volume":"275","author":"Rahil J.","year":"1991","journal-title":"Biochem. J."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1042\/bj2960389","volume":"296","author":"Rahil J.","year":"1993","journal-title":"Biochem. J."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"9664","DOI":"10.1021\/bi049309b","volume":"43","author":"Nagarajan R.","year":"2004","journal-title":"Biochemistry"},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"10763","DOI":"10.1021\/bi00091a030","volume":"32","author":"Rahil J.","year":"1993","journal-title":"Biochemistry"},{"key":"ref38\/cit38","first-page":"99","volume":"55","author":"Thatcher G. R. J.","year":"1987","journal-title":"Adv. Phys. Org. Chem."},{"key":"ref39\/cit39","volume-title":"The Enzymes","author":"Gerlt J. A.","year":"1992","edition":"3"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1021\/ar040053b","volume":"37","author":"Holmes R. R.","year":"2004","journal-title":"Acc. Chem. Res."},{"key":"ref41\/cit41","first-page":"3653","author":"Birchall J. M.","year":"1956","journal-title":"J. Chem. Soc."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1039\/b107097p","author":"Pratt R. F.","year":"2002","journal-title":"J. Chem. Soc., Perkin Trans. 2"},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"4769","DOI":"10.1016\/S0021-9258(19)43731-9","volume":"248","author":"Dunn B. M.","year":"1973","journal-title":"J. Biol. Chem."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"5457","DOI":"10.1021\/ja00384a035","volume":"104","author":"Deiters J. A.","year":"1982","journal-title":"J. Am. Chem. Soc."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"9207","DOI":"10.1021\/bi0109358","volume":"40","author":"Powers R. A.","year":"2001","journal-title":"Biochemistry"},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/S0969-2126(02)00799-2","volume":"10","author":"Powers R. A.","year":"2002","journal-title":"Structure"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi4003887","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T09:31:05Z","timestamp":1681464665000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi4003887"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,16]]},"references-count":46,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2013,5,28]]}},"alternative-id":["10.1021\/bi4003887"],"URL":"https:\/\/doi.org\/10.1021\/bi4003887","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,16]]}}}