{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T16:57:40Z","timestamp":1790528260677,"version":"4.1.0"},"reference-count":49,"publisher":"American Chemical Society (ACS)","issue":"35","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2007,9,1]]},"DOI":"10.1021\/bi700797f","type":"journal-article","created":{"date-parts":[[2007,8,14]],"date-time":"2007-08-14T11:42:34Z","timestamp":1187091754000},"page":"9929-9940","source":"Crossref","is-referenced-by-count":73,"title":["Structure and Sodium Channel Activity of an Excitatory I<sub>1<\/sub>-Superfamily Conotoxin<sup>,<\/sup>"],"prefix":"10.1021","volume":"46","author":[{"given":"Olga","family":"Buczek","sequence":"first","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daxiu","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey J.","family":"Babon","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Fiedler","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doju","family":"Yoshikami","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baldomero M.","family":"Olivera","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Bulaj","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond S.","family":"Norton","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Utah, Salt Lake City, Utah 84112, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville 3050, Australia, and Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84108"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2007,8,14]]},"reference":[{"key":"bi700797fb00001\/bi700797fb00001_1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1152\/physrev.00020.2003","volume":"84","author":"Terlau H.","year":"2004","journal-title":"Physiol. Rev."},{"key":"bi700797fb00002\/bi700797fb00002_1","volume-title":"Toxicon 48, 780\u2212798.","author":"Norton R. S.","year":"2006"},{"key":"bi700797fb00003\/bi700797fb00003_1","volume":"281","author":"Olivera B. M.","year":"2006","journal-title":"J. Biol. Chem."},{"key":"bi700797fb00004\/bi700797fb00004_1","volume-title":"Cell Mol. Life Sci. 62, 3067\u22123079.","author":"Buczek O.","year":"2005"},{"key":"bi700797fb00005\/bi700797fb00005_1","doi-asserted-by":"crossref","DOI":"10.1046\/j.1471-4159.2003.01685.x","volume":"85","author":"Jimenez E. C.","year":"2003","journal-title":"J. Neurochem."},{"key":"bi700797fb00006\/bi700797fb00006_1","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M405835200","volume":"280","author":"Buczek O.","year":"2005","journal-title":"J. Biol. Chem."},{"key":"bi700797fb00007\/bi700797fb00007_1","doi-asserted-by":"crossref","DOI":"10.1111\/j.1742-4658.2005.04830.x","volume":"272","author":"Buczek O.","year":"2005","journal-title":"FEBS J."},{"key":"bi700797fb00008\/bi700797fb00008_1","volume-title":"Toxicon 44, 539\u2212548.","author":"Kauferstein S.","year":"2004"},{"key":"bi700797fb00009\/bi700797fb00009_1","volume":"278","author":"Fan C. X.","year":"2003","journal-title":"J. Biol. Chem."},{"key":"bi700797fb00010\/bi700797fb00010_1","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S0041-0101(03)00099-0","volume":"42","author":"Kauferstein S.","year":"2003","journal-title":"Toxicon"},{"key":"bi700797fb00011\/bi700797fb00011_1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0041-0101(00)00157-4","volume":"39","author":"Olivera B. M.","year":"2001","journal-title":"Toxicon"},{"key":"bi700797fb00012\/bi700797fb00012_1","volume-title":"Nat. Struct. Biol. 7, 505\u2212513.","author":"Wang X.","year":"2000"},{"key":"bi700797fb00013\/bi700797fb00013_1","volume-title":"Mol. Pharmacol. 44, 681\u2212688.","author":"Adams M. E.","year":"1993"},{"key":"bi700797fb00014\/bi700797fb00014_1","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M202297200","volume":"277","author":"Maggio F.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"bi700797fb00015\/bi700797fb00015_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0014-5793(97)01452-X","volume":"419","author":"Pallaghy P. K.","year":"1997","journal-title":"FEBS Lett."},{"key":"bi700797fb00016\/bi700797fb00016_1","doi-asserted-by":"crossref","unstructured":"Fletcher, J. I., Chapman, B. E., Mackay, J. P., Howden, M. E., and King, G. F. (1997) The structure of versutoxin (\u03b4-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel,Structure 5, 1525\u22121535.","DOI":"10.1016\/S0969-2126(97)00301-8"},{"key":"bi700797fb00017\/bi700797fb00017_1","volume-title":"Protein Sci. 2, 1732\u22121748.","author":"Gray W. R.","year":"1993"},{"key":"bi700797fb00018\/bi700797fb00018_1","volume":"93","author":"Gibbs S. J.","year":"1991","journal-title":"J. Magn. Reson."},{"key":"bi700797fb00019\/bi700797fb00019_1","doi-asserted-by":"crossref","DOI":"10.1007\/BF00197813","volume":"6","author":"Dingley A. J.","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"bi700797fb00020\/bi700797fb00020_1","volume":"16","author":"Yao S.","year":"2000","journal-title":"J. Biomol. NMR"},{"key":"bi700797fb00021\/bi700797fb00021_1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/BF00417486","volume":"6","author":"Bartels C.","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"bi700797fb00022\/bi700797fb00022_1","volume":"93","author":"Palmer A. G.","year":"1991","journal-title":"J. Magn. Reson."},{"key":"bi700797fb00023\/bi700797fb00023_1","volume":"114","author":"Kay L. E.","year":"1992","journal-title":"J. Am. Chem. Soc."},{"key":"bi700797fb00024\/bi700797fb00024_1","doi-asserted-by":"crossref","DOI":"10.1016\/S0022-2836(02)00241-3","volume":"319","author":"Herrmann T.","year":"2002","journal-title":"J. Mol. Biol."},{"key":"bi700797fb00025\/bi700797fb00025_1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S1090-7807(02)00014-9","volume":"160","author":"Schwieters C. D.","year":"2003","journal-title":"J. Magn. Reson."},{"key":"bi700797fb00026\/bi700797fb00026_1","doi-asserted-by":"crossref","DOI":"10.1007\/BF00228148","volume":"8","author":"Laskowski R. A.","year":"1996","journal-title":"J. Biomol. NMR"},{"key":"bi700797fb00027\/bi700797fb00027_1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/0263-7855(96)00009-4","volume":"14","author":"Koradi R.","year":"1996","journal-title":"J. Mol. Graphics"},{"key":"bi700797fb00028\/bi700797fb00028_1","volume-title":"The PyMol Molecular Graphics System","author":"DeLano W. L.","year":"2002"},{"key":"bi700797fb00029\/bi700797fb00029_1","volume-title":"Proteins 11, 281\u2212296.","author":"Nicholls A.","year":"1991"},{"key":"bi700797fb00030\/bi700797fb00030_1","doi-asserted-by":"crossref","DOI":"10.1007\/BF01875516","volume":"1","author":"Seavey B. R.","year":"1991","journal-title":"J. Biomol. NMR"},{"key":"bi700797fb00031\/bi700797fb00031_1","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/BF00227471","volume":"5","author":"Wishart D. S.","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"bi700797fb00032\/bi700797fb00032_1","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M605403200","volume":"282","author":"Corzo G.","year":"2007","journal-title":"J. Biol. Chem."},{"key":"bi700797fb00033\/bi700797fb00033_1","volume-title":"Protein Sci. 3","author":"Pallaghy P. K.","year":"1994"},{"key":"bi700797fb00034\/bi700797fb00034_1","volume-title":"Toxicon 36, 1573\u22121583.","author":"Norton R. S.","year":"1998"},{"key":"bi700797fb00035\/bi700797fb00035_1","volume":"277","author":"Miles L. A.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"bi700797fb00036\/bi700797fb00036_1","volume-title":"Nucleic Acids Res. 28, 235\u2212242.","author":"Berman H. M.","year":"2000"},{"key":"bi700797fb00037\/bi700797fb00037_1","volume-title":"Nucleic Acids Res. 26, 316\u2212319.","author":"Holm L.","year":"1998"},{"key":"bi700797fb00038\/bi700797fb00038_1","volume-title":"Biochemistry 32, 13123\u221213129.","author":"Yu H.","year":"1993"},{"key":"bi700797fb00039\/bi700797fb00039_1","volume":"250","author":"Kim J. I.","year":"1995","journal-title":"J. Mol. Biol."},{"key":"bi700797fb00040\/bi700797fb00040_1","volume-title":"Mol. Pharmacol. 46, 587\u2212593.","author":"Kuwada M.","year":"1994"},{"key":"bi700797fb00041\/bi700797fb00041_1","doi-asserted-by":"crossref","DOI":"10.1007\/BF00208803","volume":"5","author":"Reily M. D.","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"bi700797fb00042\/bi700797fb00042_1","volume-title":"Proc. Natl. Acad. Sci. U.S.A. 97","author":"Caldwell J. H.","year":"2000"},{"key":"bi700797fb00043\/bi700797fb00043_1","doi-asserted-by":"crossref","DOI":"10.1002\/jnr.20073","volume":"76","author":"Rasband M. N.","year":"2004","journal-title":"J. Neurosci. Res."},{"key":"bi700797fb00044\/bi700797fb00044_1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1113\/jphysiol.2006.106815","volume":"573","author":"Schwarz J. R.","year":"2006","journal-title":"J. Physiol."},{"key":"bi700797fb00045\/bi700797fb00045_1","volume":"270","author":"McIntosh J. M.","year":"1995","journal-title":"J. Biol. Chem."},{"key":"bi700797fb00046\/bi700797fb00046_1","first-page":"38","volume":"273","author":"Shon K. J.","year":"1998","journal-title":"J. Biol. Chem."},{"key":"bi700797fb00047\/bi700797fb00047_1","volume-title":"Peptides 26, 361\u2212367.","author":"Kauferstein S.","year":"2005"},{"key":"bi700797fb00048\/bi700797fb00048_1","volume":"94","author":"West P. J.","year":"2005","journal-title":"J. Neurophysiol."},{"key":"bi700797fn00001\/bi700797fn00001_1","volume-title":"iodoacetic acid","author":"Abbreviations IAA"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi700797f","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T23:42:20Z","timestamp":1680219740000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi700797f"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8,14]]},"references-count":49,"journal-issue":{"issue":"35","published-print":{"date-parts":[[2007,9,1]]}},"alternative-id":["10.1021\/bi700797f"],"URL":"https:\/\/doi.org\/10.1021\/bi700797f","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,8,14]]}}}