{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:29:43Z","timestamp":1791930583181,"version":"4.3.4"},"reference-count":58,"publisher":"American Chemical Society (ACS)","issue":"48","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2008,12,2]]},"DOI":"10.1021\/bi8014357","type":"journal-article","created":{"date-parts":[[2008,11,7]],"date-time":"2008-11-07T09:02:20Z","timestamp":1226048540000},"page":"12689-12697","source":"Crossref","is-referenced-by-count":168,"title":["Structures of Rat and Human Islet Amyloid Polypeptide IAPP<sub>1\u221219<\/sub> in Micelles by NMR Spectroscopy"],"prefix":"10.1021","volume":"47","author":[{"given":"Ravi Prakash Reddy","family":"Nanga","sequence":"first","affiliation":[{"name":"Departments of Biophysics and Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055, and Department of Chemistry, Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Brender","sequence":"additional","affiliation":[{"name":"Departments of Biophysics and Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055, and Department of Chemistry, Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiadi","family":"Xu","sequence":"additional","affiliation":[{"name":"Departments of Biophysics and Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055, and Department of Chemistry, Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluigi","family":"Veglia","sequence":"additional","affiliation":[{"name":"Departments of Biophysics and Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055, and Department of Chemistry, Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayyalusamy","family":"Ramamoorthy","sequence":"additional","affiliation":[{"name":"Departments of Biophysics and Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055, and Department of Chemistry, Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2008,11,7]]},"reference":[{"key":"ref1\/cit1","first-page":"94","volume":"7","author":"Bailey C. J.","year":"1999","journal-title":"Diabetes Rev."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1210\/edrv-15-2-163","volume":"15","author":"Cooper G. J. S.","year":"1994","journal-title":"Endocr. Rev."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1038\/oby.2002.147","volume":"10","author":"Reda T. K.","year":"2002","journal-title":"Obes. Res."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"5950","DOI":"10.1111\/j.1742-4658.2005.05025.x","volume":"272","author":"Makin O. S.","year":"2005","journal-title":"FEBS J."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s00125-003-1304-4","volume":"47","author":"Clark A.","year":"2004","journal-title":"Diabetologia"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"10427","DOI":"10.1073\/pnas.0502066102","volume":"102","author":"Quist A.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"17294","DOI":"10.1074\/jbc.M500997200","volume":"280","author":"Demuro A.","year":"2005","journal-title":"J. Biol. Chem."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"46363","DOI":"10.1074\/jbc.C400260200","volume":"279","author":"Kayed R.","year":"2004","journal-title":"J. Biol. Chem."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1080\/15216540701283882","volume":"59","author":"Ferreira S. T.","year":"2007","journal-title":"IUBMB Life"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"6033","DOI":"10.1073\/pnas.0708354105","volume":"105","author":"Engel M. F.","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.febslet.2004.09.075","volume":"577","author":"Sparr E.","year":"2004","journal-title":"FEBS Lett."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"6424","DOI":"10.1021\/ja710484d","volume":"130","author":"Brender J. R.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.jmb.2005.12.020","volume":"356","author":"Engel M. F. M.","year":"2006","journal-title":"J. Mol. Biol."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1529\/biophysj.107.110635","volume":"93","author":"Lopes D. H. J.","year":"2007","journal-title":"Biophys. J."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.1073\/pnas.87.13.5036","volume":"87","author":"Westermark P.","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1006\/jmbi.2001.4593","volume":"308","author":"Jaikaran E.","year":"2001","journal-title":"J. Mol. Biol."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/S0022-2836(02)00887-2","volume":"322","author":"Mazor Y.","year":"2002","journal-title":"J. Mol. Biol."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"9496","DOI":"10.1021\/bi060579z","volume":"45","author":"Knight J. D.","year":"2006","journal-title":"Biochemistry"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"12680","DOI":"10.1021\/bi801427c","volume":"47","author":"Brender J. R.","year":"2008","journal-title":"Biochemistry"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"6352","DOI":"10.1021\/bi800503j","volume":"47","author":"Radovan D.","year":"2008","journal-title":"Biochemistry"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"17205","DOI":"10.1074\/jbc.M801383200","volume":"283","author":"Apostolidou M.","year":"2008","journal-title":"J. Biol. Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"5642","DOI":"10.1046\/j.1432-1033.2002.03271.x","volume":"269","author":"Crescenzi O.","year":"2002","journal-title":"Eur. J. Biochem."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1017\/S003358359800345X","volume":"31","author":"Buck M.","year":"1998","journal-title":"Q. Rev. Biophys."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"S24\u2212S40","DOI":"10.1002\/mrc.1816","volume":"44","author":"Sanders C. R.","year":"2006","journal-title":"Magn. Reson. Chem."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1016\/S0006-3495(03)74681-5","volume":"85","author":"Zamoon J.","year":"2003","journal-title":"Biophys. J."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.jmb.2006.02.047","volume":"358","author":"Traaseth N. J.","year":"2006","journal-title":"J. Mol. Biol."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"4747","DOI":"10.1073\/pnas.0406039102","volume":"102","author":"Zamoon J.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1023\/A:1008289624496","volume":"11","author":"Vinogradova O.","year":"1998","journal-title":"J. Biomol. NMR"},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"5793","DOI":"10.1021\/bi0601813","volume":"45","author":"Porcelli F.","year":"2006","journal-title":"Biochemistry"},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"5565","DOI":"10.1021\/bi702036s","volume":"47","author":"Porcelli F.","year":"2008","journal-title":"Biochemistry"},{"key":"ref31\/cit31","first-page":"355","volume":"65","author":"Bax A.","year":"1985","journal-title":"J. Magn. Reson."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-291X(80)90695-6","volume":"95","author":"Kumar A.","year":"1980","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF00197809","volume":"6","author":"Delaglio F.","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"ref34\/cit34","first-page":"254","author":"Kneller D. G.","year":"1993","journal-title":"J. Cell. Biochem."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","DOI":"10.1051\/epn\/19861701011","volume-title":"NMR of Proteins and Nucleic Acids","author":"Wuthrich K.","year":"1986"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/protein\/2.1.27","volume":"2","author":"Nilges M.","year":"1988","journal-title":"Protein Eng."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S1090-7807(02)00014-9","volume":"160","author":"Schwieters C. D.","year":"2003","journal-title":"J. Magn. Reson."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1023\/A:1008392405740","volume":"13","author":"Cornilescu G.","year":"1999","journal-title":"J. Biomol. NMR"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1007\/BF00228148","volume":"8","author":"Laskowski R. A.","year":"1996","journal-title":"J. Biomol. NMR"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0263-7855(96)00009-4","volume":"14","author":"Koradi R.","year":"1996","journal-title":"J. Mol. Graphics"},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1017\/S0033583506004422","volume":"39","author":"Lashuel H. A.","year":"2006","journal-title":"Q. Rev. Biophys."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1210\/er.2007-0037","volume":"29","author":"Haataja L.","year":"2008","journal-title":"Endocr. Rev."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"12113","DOI":"10.1021\/bi050840w","volume":"44","author":"Jayasinghe S. A.","year":"2005","journal-title":"Biochemistry"},{"key":"ref44\/cit44a","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.jmb.2003.11.046","volume":"335","author":"Bokvist M.","year":"2004","journal-title":"J. Mol. Biol."},{"key":"ref44\/cit44b","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/(SICI)1097-0282(199801)45:1<9::AID-BIP2>3.0.CO;2-X","volume":"45","author":"Ilangovan U.","year":"1998","journal-title":"Biopolymers"},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"9443","DOI":"10.1074\/jbc.273.16.9443","volume":"273","author":"Davidson W. S.","year":"1998","journal-title":"J. Biol. Chem."},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1002\/bip.10305","volume":"69","author":"Mascioni A.","year":"2003","journal-title":"Biopolymers"},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1006\/jmbi.1999.3422","volume":"295","author":"Tenidis K.","year":"2000","journal-title":"J. Mol. Biol."},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1110\/ps.062486907","volume":"16","author":"Williamson J. A.","year":"2007","journal-title":"Protein Sci."},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"9900","DOI":"10.1021\/bi800828u","volume":"47","author":"Yonemoto I. T.","year":"2008","journal-title":"Biochemistry"},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s10858-007-9176-4","volume":"39","author":"Jarvet J.","year":"2007","journal-title":"J. Biomol. NMR"},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1529\/biophysj.106.097543","volume":"94","author":"Daily A. E.","year":"2008","journal-title":"Biophys. J."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/j.febslet.2004.12.085","volume":"579","author":"Balali-Mood K.","year":"2005","journal-title":"FEBS Lett."},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1002\/(SICI)1097-0134(19980815)32:3<314::AID-PROT7>3.0.CO;2-H","volume":"32","author":"Motta A.","year":"1998","journal-title":"Proteins"},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1186\/1471-2105-7-382","volume":"7","author":"Roberts E.","year":"2006","journal-title":"BMC Bioinf."},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0263-7855(96)00018-5","volume":"14","author":"Humphrey W.","year":"1996","journal-title":"J. Mol. Graphics"},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"8459","DOI":"10.1021\/bi036284s","volume":"43","author":"Henzler-Wildman K. A.","year":"2004","journal-title":"Biochemistry"},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.bbamem.2006.02.014","volume":"1758","author":"Ramamoorthy A.","year":"2006","journal-title":"Biochim. Biophys. Acta"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi8014357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T00:47:06Z","timestamp":1678322826000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi8014357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11,7]]},"references-count":58,"journal-issue":{"issue":"48","published-print":{"date-parts":[[2008,12,2]]}},"alternative-id":["10.1021\/bi8014357"],"URL":"https:\/\/doi.org\/10.1021\/bi8014357","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,11,7]]}}}