{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T02:12:54Z","timestamp":1790388774304,"version":"4.1.0"},"reference-count":34,"publisher":"American Chemical Society (ACS)","issue":"32","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[1999,8,1]]},"DOI":"10.1021\/bi990721e","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T05:32:25Z","timestamp":1027661545000},"page":"10239-10246","source":"Crossref","is-referenced-by-count":59,"title":["The Crystal Structure of Exfoliative Toxin B:\u2009 A Superantigen with Enzymatic Activity<sup>,<\/sup>"],"prefix":"10.1021","volume":"38","author":[{"given":"Gregory M.","family":"Vath","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Molecular Biology, and Biophysics and Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, and Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathleen A.","family":"Earhart","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Molecular Biology, and Biophysics and Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, and Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dileep D.","family":"Monie","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Molecular Biology, and Biophysics and Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, and Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Iandolo","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Molecular Biology, and Biophysics and Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, and Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick M.","family":"Schlievert","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Molecular Biology, and Biophysics and Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, and Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas H.","family":"Ohlendorf","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Molecular Biology, and Biophysics and Department of Microbiology, University of Minnesota Medical School, Minneapolis, Minnesota 55455, and Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[1999,7,13]]},"reference":[{"key":"bi990721eb00001\/bi990721eb00001_1","doi-asserted-by":"crossref","DOI":"10.1093\/infdis\/125.2.129","volume":"125","author":"Melish M. F.","year":"1972","journal-title":"J. Infect. Dis."},{"key":"bi990721eb00002\/bi990721eb00002_1","doi-asserted-by":"crossref","DOI":"10.1042\/bj2840177","volume":"284","author":"Bailey C. J.","year":"1992","journal-title":"Biochem. J."},{"key":"bi990721eb00003\/bi990721eb00003_1","doi-asserted-by":"crossref","DOI":"10.1111\/j.1574-6968.1991.tb04738.x","volume":"81","author":"Redpath M. B.","year":"1991","journal-title":"FEMS Microbiol. Lett."},{"key":"bi990721eb00004\/bi990721eb00004_1","volume-title":"Infect. Immun. 59, 3337\u22123339","author":"Prevost G.","year":"1991"},{"key":"bi990721eb00005\/bi990721eb00005_1","first-page":"489","volume-title":"B.","author":"Prevost G.","year":"1992"},{"key":"bi990721eb00006\/bi990721eb00006_1","volume-title":"Biochemistry 36, 1559\u22121566","author":"Vath G. M.","year":"1997"},{"key":"bi990721eb00007\/bi990721eb00007_1","volume-title":"Structure 5, 813\u2212824","author":"Cavarelli J.","year":"1997"},{"key":"bi990721eb00008\/bi990721eb00008_1","first-page":"36","volume":"165","author":"De Azavedo C. S.","year":"1988","journal-title":"Methods. Enzymol."},{"key":"bi990721eb00009\/bi990721eb00009_1","volume-title":"Infect. Immun. 30, 381\u2212384","author":"Morlock B. A.","year":"1980"},{"key":"bi990721eb00010\/bi990721eb00010_1","volume-title":"Science 248, 705\u2212711","author":"Marrack P.","year":"1990"},{"key":"bi990721eb00011\/bi990721eb00011_1","first-page":"35","volume":"56","author":"White J.","year":"1989","journal-title":"Cell"},{"key":"bi990721eb00012\/bi990721eb00012_1","doi-asserted-by":"crossref","DOI":"10.3109\/10408419009105728","volume":"17","author":"Bohach G. A.","year":"1990","journal-title":"Crit. Rev. Microbiol."},{"key":"bi990721eb00013\/bi990721eb00013_1","doi-asserted-by":"crossref","DOI":"10.4049\/jimmunol.162.8.4550","volume":"162","author":"Monday S. R.","year":"1999","journal-title":"J. Immunol."},{"key":"bi990721eb00014\/bi990721eb00014_1","volume-title":"Infect. Immun. 65, 4048\u22124054","author":"Deringer J. R.","year":"1997"},{"key":"bi990721eb00015\/bi990721eb00015_1","volume":"131","author":"Kim Y. B.","year":"1970","journal-title":"J. Exp. Med."},{"key":"bi990721eb00016\/bi990721eb00016_1","doi-asserted-by":"crossref","DOI":"10.1128\/jb.166.2.574-580.1986","volume":"166","author":"Jackson M.","year":"1986","journal-title":"J. Bacteriol."},{"key":"bi990721eb00017\/bi990721eb00017_1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0076-6879(88)65010-5","volume":"165","author":"Blomster-Hautamaa D. A.","year":"1988","journal-title":"Methods Enzymol."},{"key":"bi990721eb00018\/bi990721eb00018_1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0022-2836(84)90448-0","volume":"175","author":"Moras D.","year":"1984","journal-title":"J. Mol. Biol."},{"key":"bi990721eb00019\/bi990721eb00019_1","volume":"20","author":"Howard A. J.","year":"1987","journal-title":"J. Appl. Crystallogr."},{"key":"bi990721eb00020\/bi990721eb00020_1","volume":"50","author":"Collaborative Computational Project, Number 4","year":"1994","journal-title":"Acta Crystallogr."},{"key":"bi990721eb00021\/bi990721eb00021_1","volume-title":"X-PLOR Version 3:\u2009 A system for Crystallography and NMR","author":"Br\u00fcnger A. T.","year":"1990"},{"key":"bi990721eb00022\/bi990721eb00022_1","doi-asserted-by":"crossref","DOI":"10.1002\/j.1460-2075.1989.tb08511.x","volume":"8","author":"Bode W.","year":"1989","journal-title":"EMBO J."},{"key":"bi990721eb00023\/bi990721eb00023_1","volume":"47","author":"Jones A. T.","year":"1991","journal-title":"Acta Crystallogr."},{"key":"bi990721eb00024\/bi990721eb00024_1","volume-title":"Funct., Genet. 11(4), 281\u2212296.","author":"Nicholls A.","year":"1991"},{"key":"bi990721eb00025\/bi990721eb00025_1","doi-asserted-by":"crossref","DOI":"10.1107\/S0021889892009944","volume":"26","author":"Laskowski R. A.","year":"1993","journal-title":"J. Appl. Crystallogr."},{"key":"bi990721eb00026\/bi990721eb00026_1","doi-asserted-by":"crossref","DOI":"10.1016\/0263-7855(93)87009-T","volume":"11","author":"Evans S. V.","year":"1993","journal-title":"J. Mol. Graphics"},{"key":"bi990721eb00027\/bi990721eb00027_1","volume-title":"Protein Sci. 4, 337\u2212360","author":"Perona J. J.","year":"1995"},{"key":"bi990721eb00028\/bi990721eb00028_1","volume-title":"Biochem. Biophys. Res. Commun. 27, 157\u2212162","author":"Schechter I.","year":"1968"},{"key":"bi990721eb00029\/bi990721eb00029_1","volume-title":"Biochemistry 31, 3059\u22123064","author":"McGrath M. E.","year":"1992"},{"key":"bi990721eb00030\/bi990721eb00030_1","doi-asserted-by":"crossref","DOI":"10.1146\/annurev.bb.11.060182.002223","volume":"11","author":"Steitz T. A.","year":"1982","journal-title":"Annu. Rev. Biophys. Bioeng."},{"key":"bi990721eb00031\/bi990721eb00031_1","doi-asserted-by":"crossref","DOI":"10.1107\/S010876818300275X","volume":"39","author":"Marquart M.","year":"1983","journal-title":"Acta Crystallogr., Sect. B"},{"key":"bi990721eb00032\/bi990721eb00032_1","volume-title":"Nature 384, 188\u2212192","author":"Fields B. A.","year":"1996"},{"key":"bi990721en00001\/bi990721en00001_1","volume-title":"exfoliative toxins","author":"Abbreviations"},{"key":"bi990721en00004\/bi990721en00004_1","unstructured":"Loops are named as described in Perona and Craik (28). Loop C is defined as residues 106(90)\u2212115(103) in ETB and residues 112(90)\u2212121(103) in ETA; loop D is residues 155(141)\u2212164(155) in ETB and residues 161(141)\u2212170(155) in ETA; loop 2 is residues 206(218)\u2212209(224) in ETB and residues 215(218)\u2212222(224) in ETA; and loop 3 is residues 171(162)\u2212175(181) in ETB and residues 177(162)\u2212184(181) in ETA."}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi990721e","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,19]],"date-time":"2023-04-19T21:59:06Z","timestamp":1681941546000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi990721e"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,7,13]]},"references-count":34,"journal-issue":{"issue":"32","published-print":{"date-parts":[[1999,8,1]]}},"alternative-id":["10.1021\/bi990721e"],"URL":"https:\/\/doi.org\/10.1021\/bi990721e","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,7,13]]}}}