{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:05:06Z","timestamp":1787000706022,"version":"build-2736575974"},"reference-count":32,"publisher":"American Chemical Society (ACS)","issue":"15","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2000,4,1]]},"DOI":"10.1021\/bi992952r","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T01:51:53Z","timestamp":1027648313000},"page":"4217-4224","source":"Crossref","is-referenced-by-count":82,"title":["Structural Basis for the Catalytic Mechanism of a Proficient Enzyme:\u2009 Orotidine 5\u2018-Monophosphate Decarboxylase\n                    <sup>,<\/sup>"],"prefix":"10.1021","volume":"39","author":[{"given":"Pernille","family":"Harris","sequence":"first","affiliation":[{"name":"Centre for Crystallographic Studies, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark, and Institute of Molecular Biology, University of Copenhagen, S\u00f8lvgade 83H, B07 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens-Christian","family":"Navarro Poulsen","sequence":"additional","affiliation":[{"name":"Centre for Crystallographic Studies, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark, and Institute of Molecular Biology, University of Copenhagen, S\u00f8lvgade 83H, B07 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaj Frank","family":"Jensen","sequence":"additional","affiliation":[{"name":"Centre for Crystallographic Studies, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark, and Institute of Molecular Biology, University of Copenhagen, S\u00f8lvgade 83H, B07 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sine","family":"Larsen","sequence":"additional","affiliation":[{"name":"Centre for Crystallographic Studies, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen, Denmark, and Institute of Molecular Biology, University of Copenhagen, S\u00f8lvgade 83H, B07 Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2000,3,23]]},"reference":[{"key":"bi992952rb00001\/bi992952rb00001_1","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1126\/science.7809611","volume":"267","author":"Radzicka A.","year":"1995","journal-title":"Science"},{"key":"bi992952rb00002\/bi992952rb00002_1","first-page":"78","volume":"53","author":"Traut T. W.","year":"1996","journal-title":"Prog. Nucleic Acid Res. Mol. Biol."},{"key":"bi992952rb00003\/bi992952rb00003_1","volume-title":"Biochemistry 33, 1287\u22121294","author":"Scapin G.","year":"1994"},{"key":"bi992952rb00004\/bi992952rb00004_1","volume-title":"Biochemistry 35, 3803\u22123809","author":"Henriksen A.","year":"1996"},{"key":"bi992952rb00005\/bi992952rb00005_1","volume-title":"Biochemistry 38, 275\u2212283","author":"Wang G. P.","year":"1999"},{"key":"bi992952rb00006\/bi992952rb00006_1","doi-asserted-by":"crossref","first-page":"6434","DOI":"10.1021\/ja00387a047","volume":"104","author":"Silverman R. B.","year":"1982","journal-title":"J. Am. Chem. Soc."},{"key":"bi992952rb00007\/bi992952rb00007_1","volume-title":"Biochemistry 29, 3198\u22123202","author":"Acheson S. A.","year":"1990"},{"key":"bi992952rb00008\/bi992952rb00008_1","volume-title":"Biochemistry 31, 12155\u221212161","author":"Shostak K.","year":"1992"},{"key":"bi992952rb00009\/bi992952rb00009_1","volume":"98","author":"Beak P.","year":"1976","journal-title":"J. Am. Chem. Soc."},{"key":"bi992952rb00010\/bi992952rb00010_1","volume-title":"Science 276, 942\u2212945","author":"Lee J. K.","year":"1997"},{"key":"bi992952rb00011\/bi992952rb00011_1","volume-title":"Biochemistry 31, 12162\u221212168","author":"Smiley J. A.","year":"1992"},{"key":"bi992952rb00012\/bi992952rb00012_1","volume":"266","author":"Bell J. B.","year":"1991","journal-title":"J. Biol. Chem."},{"key":"bi992952rb00013\/bi992952rb00013_1","volume-title":"Biochemistry 19, 4993\u22124999","author":"Levine H. L.","year":"1980"},{"key":"bi992952rb00014\/bi992952rb00014_1","volume-title":"Biochemistry 30, 6216\u22126223","author":"Smiley J. A.","year":"1991"},{"key":"bi992952rb00015\/bi992952rb00015_1","volume-title":"Manuscript to be published","author":"Poulsen J.-C. N.","year":"1999"},{"key":"bi992952rb00016\/bi992952rb00016_1","volume-title":"The HKL-manual:\u2009 On oscillation Data Processing Suite for Macromolecular Crystallography","author":"Gerwith D.","year":"1999"},{"key":"bi992952rb00017\/bi992952rb00017_1","volume":"50","author":"The","year":"1994","journal-title":"Acta Crystallogr. D"},{"key":"bi992952rb00018\/bi992952rb00018_1","volume":"55","author":"Terwilliger T. C.","year":"1999","journal-title":"Acta Crystallogr. D"},{"key":"bi992952rb00019\/bi992952rb00019_1","volume-title":"TURBO-FRODO biographics and AFMP. Architecture et Function des Macromol\u00e9cules Biologique","author":"Roussel A.","year":"1992"},{"key":"bi992952rb00020\/bi992952rb00020_1","doi-asserted-by":"crossref","DOI":"10.1107\/S0907444998003254","volume":"54","author":"Br\u00fcnger A. T.","year":"1998","journal-title":"Acta Crystallogr. D"},{"key":"bi992952rb00021\/bi992952rb00021_1","volume-title":"unpublished results","author":"Harris P.","year":"1999"},{"key":"bi992952rb00022\/bi992952rb00022_1","volume-title":"Protein Sci. 7, 1269\u22121279","author":"Rowland P.","year":"1998"},{"key":"bi992952rb00023\/bi992952rb00023_1","doi-asserted-by":"crossref","DOI":"10.1021\/j100025a013","volume":"99","author":"Flensburg C.","year":"1995","journal-title":"J. Phys. Chem."},{"key":"bi992952rb00024\/bi992952rb00024_1","doi-asserted-by":"crossref","DOI":"10.1021\/jp972419q","volume":"102","author":"Madsen D.","year":"1998","journal-title":"J. Phys. Chem. A"},{"key":"bi992952rb00025\/bi992952rb00025_1","doi-asserted-by":"crossref","first-page":"3639","DOI":"10.1021\/ja00507a059","volume":"101","author":"Abu-Dari K.","year":"1979","journal-title":"J. Am. Chem. Soc."},{"key":"bi992952rb00026\/bi992952rb00026_1","unstructured":"March, J. (1992) in\n                      Advances in Organic Chemistry\n                      , pp 628, Wiley, New York."},{"key":"bi992952rb00027\/bi992952rb00027_1","volume":"121","author":"Erhlich J. I.","year":"1999","journal-title":"J. Am. Chem. Soc."},{"key":"bi992952rb00028\/bi992952rb00028_1","doi-asserted-by":"crossref","DOI":"10.1107\/S0021889891004399","volume":"24","author":"Kraulis P. J.","year":"1991","journal-title":"J. Appl. Crystallogr."},{"key":"bi992952rb00029\/bi992952rb00029_1","volume-title":"Methods Enzymol. 277, 505\u2212524","author":"Merrit E. A.","year":"1999"},{"key":"bi992952rb00030\/bi992952rb00030_1","volume-title":"Protein Eng. 8, 127\u2212134","author":"Wallace A. C.","year":"1995"},{"key":"bi992952rb00031\/bi992952rb00031_1","volume":"50","author":"Jones T.","year":"1991","journal-title":"Acta Crystallogr. D"},{"key":"bi992952rn00001\/bi992952rn00001_1","volume-title":"orotidine 5\u2018-monophosphate decarboxylase","author":"Abbreviations"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bi992952r","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,17]],"date-time":"2021-10-17T14:56:30Z","timestamp":1634482590000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bi992952r"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,3,23]]},"references-count":32,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2000,4,1]]}},"alternative-id":["10.1021\/bi992952r"],"URL":"https:\/\/doi.org\/10.1021\/bi992952r","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,3,23]]}}}