{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T08:03:06Z","timestamp":1774425786551,"version":"3.50.1"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2012,5,14]]},"DOI":"10.1021\/bm300135h","type":"journal-article","created":{"date-parts":[[2012,3,19]],"date-time":"2012-03-19T14:47:03Z","timestamp":1332168423000},"page":"1400-1409","source":"Crossref","is-referenced-by-count":22,"title":["Enhanced Self-Association of Mucins Possessing the T and Tn Carbohydrate Cancer Antigens at the Single-Molecule Level"],"prefix":"10.1021","volume":"13","author":[{"given":"Kristin E.","family":"Haugstad","sequence":"first","affiliation":[{"name":"Biophysics and Medical Technology, Department of Physics, The Norwegian University of Science and Technology, NO-7491 Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Gerken","sequence":"additional","affiliation":[{"name":"W. A. Bernbaum Center for Cystic\rFibrosis Research, Departments of Pediatrics and Biochemistry, Case Western Reserve University, School\rof Medicine, Cleveland, Ohio 44106-4948, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f8rn T.","family":"Stokke","sequence":"additional","affiliation":[{"name":"Biophysics and Medical Technology, Department of Physics, The Norwegian University of Science and Technology, NO-7491 Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarun K.","family":"Dam","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Michigan Technological University, Houghton,\rMichigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Fred","family":"Brewer","sequence":"additional","affiliation":[{"name":"Departments of Molecular\rPharmacology and Microbiology and Immunology, Albert Einstein College of Medicine,\rBronx, New York 10461, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marit","family":"Sletmoen","sequence":"additional","affiliation":[{"name":"Biophysics and Medical Technology, Department of Physics, The Norwegian University of Science and Technology, NO-7491 Trondheim, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2012,4,3]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"5021","DOI":"10.1016\/j.bmc.2005.04.085","volume":"13","author":"Hang H. C.","year":"2005","journal-title":"Bioorg. Med. Chem."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.sbi.2004.08.006","volume":"14","author":"Bucior I.","year":"2004","journal-title":"Curr. Opin. Struct. Biol."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1166\/sl.2009.1148","volume":"7","author":"Rodriguez-Segui S. A.","year":"2009","journal-title":"Sens. Lett."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"6192","DOI":"10.1021\/ja0431354","volume":"127","author":"de la Fuente J. M.","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1002\/1521-3773(20010618)40:12<2257::AID-ANIE2257>3.0.CO;2-S","volume":"40","author":"de la Fuente J. M.","year":"2001","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1002\/1521-3773(20020503)41:9<1554::AID-ANIE1554>3.0.CO;2-3","volume":"41","author":"Hernaiz M. J.","year":"2002","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1146\/annurev.ph.57.030195.003025","volume":"57","author":"Lichtenberger L. M.","year":"1995","journal-title":"Annu. Rev. Physiol."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1023\/A:1025815113599","volume":"23","author":"Byrd J. C.","year":"2004","journal-title":"Cancer Metastasis Rev."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/nrc1251","volume":"4","author":"Hollingsworth M. A.","year":"2004","journal-title":"Nat. Rev. Cancer"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/nrd1751","volume":"4","author":"Dube D. H.","year":"2005","journal-title":"Nat. Rev. Drug Discovery"},{"key":"ref11\/cit11","unstructured":"Strick, R. V. a. W.; Spencer, J.Carbohydrates, the essential molecules of life,2nd ed.Elsevier:Oxford, 2009; p474."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0006-3495(99)76910-9","volume":"77","author":"McMaster T. J.","year":"1999","journal-title":"Biophys. J."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1021\/bm0505843","volume":"6","author":"Hong Z. N.","year":"2005","journal-title":"Biomacromolecules"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1093\/glycob\/cwm027","volume":"17","author":"Round A. N.","year":"2007","journal-title":"Glycobiology"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"5525","DOI":"10.1021\/bi00439a029","volume":"28","author":"Shogren R.","year":"1989","journal-title":"Biochemistry"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.carres.2007.10.005","volume":"343","author":"Maleki A.","year":"2008","journal-title":"Carbohydr. Res."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"3216","DOI":"10.1021\/bm800799u","volume":"9","author":"Di Cola E.","year":"2008","journal-title":"Biomacromolecules"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"5536","DOI":"10.1021\/bi00439a030","volume":"28","author":"Gerken T. A.","year":"1989","journal-title":"Biochemistry"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1146\/annurev.ph.57.030195.003223","volume":"57","author":"Bansil R.","year":"1995","journal-title":"Annu. Rev. Physiol."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"33204","DOI":"10.1074\/jbc.272.52.33204","volume":"272","author":"Eckhardt A. E.","year":"1997","journal-title":"J. Biol. Chem."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/S0021-9258(18)93649-5","volume":"243","author":"Carlson D. M.","year":"1968","journal-title":"J. Biol. Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"4689","DOI":"10.1021\/bi00389a015","volume":"26","author":"Gerken T. A.","year":"1987","journal-title":"Biochemistry"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"7736","DOI":"10.1074\/jbc.M111690200","volume":"277","author":"Gerken T. A.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1002\/bip.21213","volume":"91","author":"Sletmoen M.","year":"2009","journal-title":"Biopolymers"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"9709","DOI":"10.1074\/jbc.272.15.9709","volume":"272","author":"Gerken T. A.","year":"1997","journal-title":"J. Biol. Chem."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1021\/bi00118a002","volume":"31","author":"Gerken T. A.","year":"1992","journal-title":"Biochemistry"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1021\/bi00302a023","volume":"23","author":"Gerken T. A.","year":"1984","journal-title":"Biochemistry"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/S0968-0004(01)02052-7","volume":"27","author":"Dekker J.","year":"2002","journal-title":"Trends Biochem. Sci."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/0956-5663(95)99227-C","volume":"10","author":"Florin E. L.","year":"1995","journal-title":"Biosens. Bioelectron."},{"key":"ref30\/cit30","first-page":"1","author":"Evans E.","year":"1998","journal-title":"Faraday Discuss."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1016\/S0006-3495(97)78802-7","volume":"72","author":"Evans E.","year":"1997","journal-title":"Biophys. J."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1126\/science.347575","volume":"200","author":"Bell G. I.","year":"1978","journal-title":"Science"},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"15755","DOI":"10.1073\/pnas.0806085105","volume":"105","author":"Dudko O. K.","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"3477","DOI":"10.1073\/pnas.93.8.3477","volume":"93","author":"Hinterdorfer P.","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"3052","DOI":"10.1002\/1521-3773(20010817)40:16<3052::AID-ANIE3052>3.0.CO;2-Q","volume":"40","author":"Tromas C.","year":"2001","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"10174","DOI":"10.1021\/la9009515","volume":"25","author":"Takemasa M.","year":"2009","journal-title":"Langmuir"},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1126\/science.7855599","volume":"267","author":"Dammer U.","year":"1995","journal-title":"Science"},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1039\/B811426A","volume":"39","author":"Bizzarri A. R.","year":"2010","journal-title":"Chem. Soc. Rev."},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"3498","DOI":"10.1016\/j.bpj.2010.09.002","volume":"99","author":"Harder A.","year":"2010","journal-title":"Biophys. J."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"16638","DOI":"10.1073\/pnas.0505208102","volume":"102","author":"Sulchek T. A.","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1126\/science.8153628","volume":"264","author":"Moy V. T.","year":"1994","journal-title":"Science"},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1002\/jmr.1109","volume":"24","author":"Teulon J. M.","year":"2011","journal-title":"J. Mol. Recognit."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1021\/bm0345211","volume":"2004","author":"Sletmoen M.","year":"2004","journal-title":"Biomacromolecules"},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/sj.embor.7400705","volume":"7","author":"Brockhausen I.","year":"2006","journal-title":"EMBO Rep."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1126\/science.6729450","volume":"224","author":"Springer G. F.","year":"1984","journal-title":"Science"},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/glycob\/10.5.439","volume":"10","author":"Hanisch F.-G.","year":"2000","journal-title":"Glycobiology"},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1073\/pnas.012540899","volume":"99","author":"Hakomori S.","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.tcb.2006.07.006","volume":"16","author":"Singh P. K.","year":"2006","journal-title":"Trends Cell Biol."},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/S0959-440X(02)00364-0","volume":"12","author":"Brewer C. F.","year":"2002","journal-title":"Curr. Opin. Struct. Biol."},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.cell.2007.01.049","volume":"129","author":"Lau K. S.","year":"2007","journal-title":"Cell"},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1023\/B:GLYC.0000044844.95878.cf","volume":"21","author":"Hakomori S.","year":"2004","journal-title":"Glycoconjugate J."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/1040-8428(92)90087-7","volume":"12","author":"Glinksky G. V.","year":"1992","journal-title":"Crit. Rev. Oncol.\/Hematol."}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bm300135h","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T01:17:24Z","timestamp":1681521444000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bm300135h"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,3]]},"references-count":52,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,5,14]]}},"alternative-id":["10.1021\/bm300135h"],"URL":"https:\/\/doi.org\/10.1021\/bm300135h","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,3]]}}}