{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T11:17:05Z","timestamp":1778671025210,"version":"3.51.4"},"reference-count":47,"publisher":"American Chemical Society (ACS)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2012,9,10]]},"DOI":"10.1021\/bm300843u","type":"journal-article","created":{"date-parts":[[2012,8,7]],"date-time":"2012-08-07T18:48:39Z","timestamp":1344365319000},"page":"2831-2842","source":"Crossref","is-referenced-by-count":17,"title":["Biotinylated Polyacrylamide-Based Metal-Chelating Polymers and Their Influence on Antigen Recognition Following Conjugation to a Trastuzumab Fab Fragment"],"prefix":"10.1021","volume":"13","author":[{"given":"Peng","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Toronto, 80 Saint George Street, Toronto,\rOntario, Canada M5S 3H6"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda J.","family":"Boyle","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical\rSciences, University of Toronto, 144 College\rStreet, Toronto, Ontario, Canada M5S 3M2"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yijie","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Toronto, 80 Saint George Street, Toronto,\rOntario, Canada M5S 3H6"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond M.","family":"Reilly","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical\rSciences, University of Toronto, 144 College\rStreet, Toronto, Ontario, Canada M5S 3M2"},{"name":"Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada\rM5G 2M9"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell A.","family":"Winnik","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Toronto, 80 Saint George Street, Toronto,\rOntario, Canada M5S 3H6"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2012,8,7]]},"reference":[{"key":"ref1\/cit1a","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1080\/08982100500528784","volume":"16","author":"Erdogan S.","year":"2006","journal-title":"J. Liposome Res."},{"key":"ref1\/cit1b","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0927-7765(99)00155-1","volume":"18","author":"Weissig V.","year":"2000","journal-title":"Colloids Surf., B"},{"key":"ref1\/cit1c","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1002\/jmri.21202","author":"Erdogan S.","year":"2008","journal-title":"J. Magn. Reson. Imaging"},{"key":"ref1\/cit1d","unstructured":"dTorchilin, V. P.InHandbook of Targeted Delivery of Imaging Agents;CRC Press:Boca Raton, FL, 1995; pp149\u2013173."},{"key":"ref1\/cit1e","volume-title":"Stealth Liposomes","author":"Lasic D.","year":"1995"},{"key":"ref2\/cit2","first-page":"275","volume":"7","author":"Torchilin V. P.","year":"1991","journal-title":"Crit. Rev. Ther. Drug Carrier Syst."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1021\/bc9800567","volume":"10","author":"Torchilin V. P.","year":"1999","journal-title":"Bioconjugate Chem."},{"key":"ref4\/cit4","first-page":"1","volume":"5","author":"Patel K.","year":"2010","journal-title":"Mater. Matters"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1126\/science.2645643","volume":"243","author":"Grubbs R. H.","year":"1989","journal-title":"Science"},{"key":"ref6\/cit6a","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1002\/pola.10660","volume":"41","author":"Hernandez J. R.","year":"2003","journal-title":"J. Polym. Sci., Part A: Polym. Chem."},{"key":"ref6\/cit6b","doi-asserted-by":"crossref","first-page":"5528","DOI":"10.1021\/cr900049t","volume":"109","author":"Hadjichristidis N.","year":"2009","journal-title":"Chem. Rev."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1002\/pola.20134","volume":"42","author":"Carlise J. R.","year":"2004","journal-title":"J. Polym. Sci., Part A: Polym. Chem."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/marc.200900869","volume":"31","author":"Shunmgam R.","year":"2010","journal-title":"Macromol. Rapid Commun."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1002\/marc.200800083","volume":"29","author":"Shunmgam R.","year":"2008","journal-title":"Macromol. Rapid Commun."},{"key":"ref10\/cit10a","doi-asserted-by":"crossref","first-page":"6090","DOI":"10.1021\/ma025551j","volume":"35","author":"Calzia K. J.","year":"2002","journal-title":"Macromolecules"},{"key":"ref10\/cit10b","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1002\/1521-3927(20020601)23:9<561::AID-MARC561>3.0.CO;2-W","volume":"23","author":"Schubert U. S.","year":"2002","journal-title":"Macromol. Rapid Commun."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"3955","DOI":"10.1021\/ma026011p","volume":"36","author":"El-Ghayoury A.","year":"2003","journal-title":"Macromolecules"},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1021\/ma0352375","volume":"37","author":"Aamer K. A.","year":"2004","journal-title":"Macromolecules"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"13567","DOI":"10.1021\/ja053048r","volume":"127","author":"Shunmugam R.","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"5409","DOI":"10.1002\/chem.200800461","volume":"14","author":"Shunmugam R.","year":"2008","journal-title":"Chem.\u2014Eur. J."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"6813","DOI":"10.1021\/ac901049w","volume":"81","author":"Bandura D. R.","year":"2009","journal-title":"Anal. Chem."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"6111","DOI":"10.1002\/anie.200700796","volume":"46","author":"Lou X.","year":"2007","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"8961","DOI":"10.1021\/ac101901x","volume":"82","author":"Majonis D.","year":"2010","journal-title":"Anal. Chem."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1126\/science.1198704","volume":"332","author":"Bendall S. C.","year":"2011","journal-title":"Science"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.2967\/jnumed.106.037937","volume":"48","author":"Costantini D. L.","year":"2007","journal-title":"J. Nucl. Med."},{"key":"ref20\/cit20","first-page":"3","volume":"23","author":"Costantini D. L.","year":"2008","journal-title":"Cancer Biother. Radiopharm."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.2967\/jnumed.108.051771","volume":"49","author":"Costantini D. L.","year":"2008","journal-title":"J. Nucl. Med."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"5402","DOI":"10.1021\/cr9001403","volume":"109","author":"Boyer B.","year":"2009","journal-title":"Chem. Rev."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1021\/bm901249n","volume":"11","author":"York A. W.","year":"2010","journal-title":"Biomacromolecules"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"3245","DOI":"10.1039\/b804812f","volume":"28","author":"Heredia K. L.","year":"2008","journal-title":"Chem. Commun. (Cambridge, U. K.)"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1021\/bm800657e","volume":"9","author":"Jia Z.","year":"2008","journal-title":"Biomacromolecules"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1021\/mp800003u","volume":"5","author":"Pan H. Z.","year":"2008","journal-title":"Mol. Pharmaceutics"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.biomaterials.2008.09.057","volume":"30","author":"Rossi N. A. A.","year":"2009","journal-title":"Biomaterials"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1021\/bm2005774","volume":"12","author":"Allmeroth M.","year":"2011","journal-title":"Biomacromolecules"},{"key":"ref29\/cit29","unstructured":"Boyle, A. J.; Liu, P.; Lu, Y.; Weinrich, D.; Scollard, A. D.; Mbong, G. N. N.; Winnik, M. A.; Reilly, R. M.Pharm. Res. 2012, in press."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1139\/V10-134","volume":"89","author":"Li B.","year":"2011","journal-title":"Can. J. Chem."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"2531","DOI":"10.1080\/00397919608004566","volume":"26","author":"Korshun V. A.","year":"1996","journal-title":"Synth. Commun."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1039\/b210678g","volume":"1","author":"Reizelman A.","year":"2003","journal-title":"Org. Biomol. Chem."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"8513","DOI":"10.1021\/ma801681b","volume":"41","author":"Roth P. J.","year":"2008","journal-title":"Macromolecules"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"2546","DOI":"10.1021\/ja057481c","volume":"128","author":"Bathfield M.","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"3997","DOI":"10.1021\/bm201011t","volume":"12","author":"Majonis D.","year":"2011","journal-title":"Biomacromolecules"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"5851","DOI":"10.1016\/S0040-4039(00)97976-0","volume":"31","author":"Green M.","year":"1990","journal-title":"Tetrahedron Lett."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1021\/bm0702049","volume":"8","author":"You Y. Z.","year":"2007","journal-title":"Biomacromolecules"},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"7069","DOI":"10.1021\/ma071359b","volume":"40","author":"Qiu X.-P.","year":"2007","journal-title":"Macromolecules"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/pola.21042","volume":"44","author":"Thompson K.","year":"2006","journal-title":"J. Polym. Sci., Part A: Polym. Chem."},{"key":"ref40\/cit40","unstructured":"Reilly, R. M.InHandbook of Biopharmaceutical Technology,Gad, S. C., Eds.John Wiley & Sons, Ltd:Toronto, ON, 2007; pp987\u20131053."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1002\/elps.200600807","volume":"28","author":"Zheng C. Y.","year":"2007","journal-title":"Electrophoresis"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bm300843u","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T03:45:43Z","timestamp":1681443943000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bm300843u"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,7]]},"references-count":47,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012,9,10]]}},"alternative-id":["10.1021\/bm300843u"],"URL":"https:\/\/doi.org\/10.1021\/bm300843u","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,7]]}}}