{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:52:09Z","timestamp":1792605129693,"version":"4.5.0"},"reference-count":25,"publisher":"American Chemical Society (ACS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2014,5,12]]},"DOI":"10.1021\/bm401593n","type":"journal-article","created":{"date-parts":[[2014,3,26]],"date-time":"2014-03-26T19:10:04Z","timestamp":1395861004000},"page":"1560-1567","source":"Crossref","is-referenced-by-count":265,"title":["Synthesis and Cellular Uptake of Folic Acid-Conjugated Cellulose Nanocrystals for Cancer Targeting"],"prefix":"10.1021","volume":"15","author":[{"given":"Shuping","family":"Dong","sequence":"first","affiliation":[{"name":"Macromolecules and Interfaces Institute, \u2021School of Biomedical Engineering\rand Sciences, \u00a7Department of Biomedical Sciences and Pathobiology, Virginia-Maryland\rRegional College of Veterinary Medicine, and \u2225Department of Sustainable Biomaterials, Virginia Tech, Blacksburg, Virginia 24061, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung Joon","family":"Cho","sequence":"additional","affiliation":[{"name":"Macromolecules and Interfaces Institute, \u2021School of Biomedical Engineering\rand Sciences, \u00a7Department of Biomedical Sciences and Pathobiology, Virginia-Maryland\rRegional College of Veterinary Medicine, and \u2225Department of Sustainable Biomaterials, Virginia Tech, Blacksburg, Virginia 24061, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Woo","family":"Lee","sequence":"additional","affiliation":[{"name":"Macromolecules and Interfaces Institute, \u2021School of Biomedical Engineering\rand Sciences, \u00a7Department of Biomedical Sciences and Pathobiology, Virginia-Maryland\rRegional College of Veterinary Medicine, and \u2225Department of Sustainable Biomaterials, Virginia Tech, Blacksburg, Virginia 24061, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Roman","sequence":"additional","affiliation":[{"name":"Macromolecules and Interfaces Institute, \u2021School of Biomedical Engineering\rand Sciences, \u00a7Department of Biomedical Sciences and Pathobiology, Virginia-Maryland\rRegional College of Veterinary Medicine, and \u2225Department of Sustainable Biomaterials, Virginia Tech, Blacksburg, Virginia 24061, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2014,4,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1517\/17425240802567846","volume":"5","author":"Simone E. A.","year":"2008","journal-title":"Expert Opin. Drug Delivery"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/nnano.2007.70","volume":"2","author":"Geng Y.","year":"2007","journal-title":"Nat. Nanotechnol."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1002\/smll.200800323","volume":"4","author":"Lacerda L.","year":"2008","journal-title":"Small"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1021\/bm049300p","volume":"6","author":"Beck-Candanedo S.","year":"2005","journal-title":"Biomacromolecules"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0261-5614(92)90006-C","volume":"11","author":"Carstensen H.","year":"1992","journal-title":"Clin. Nutr."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0168-3659(92)90126-C","volume":"20","author":"M\u00fcller R. H.","year":"1992","journal-title":"J. Controlled Release"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/0142-9612(92)90177-P","volume":"13","author":"Norman M. E.","year":"1992","journal-title":"Biomaterials"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.ejpb.2004.02.016","volume":"58","author":"Lemarchand C.","year":"2004","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijpharm.2005.10.010","volume":"307","author":"Owens D. E.","year":"2006","journal-title":"Int. J. Pharm."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"4356","DOI":"10.1016\/j.biomaterials.2006.03.039","volume":"27","author":"Vonarbourg A.","year":"2006","journal-title":"Biomaterials"},{"key":"ref11\/cit11","first-page":"81","volume-title":"Polysaccharide Materials: Performance by Design","author":"Roman M.","year":"2009"},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1241006","DOI":"10.1142\/S1793984412410061","volume":"2","author":"Dong S.","year":"2012","journal-title":"Nano LIFE"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"13810","DOI":"10.1021\/ja076196l","volume":"129","author":"Dong S.","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1021\/am1006222","volume":"2","author":"Mahmoud K. A.","year":"2010","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.7785\/tcrt.2012.500428"},{"key":"ref16\/cit16","first-page":"102","volume":"10","author":"Arena C. B.","year":"2011","journal-title":"Biomed. Eng."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"681","DOI":"10.3171\/2010.5.JNS091448","volume":"114","author":"Ellis T. L.","year":"2011","journal-title":"J. Neurosurg."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"73","DOI":"10.7785\/tcrt.2012.500181","volume":"10","author":"Garcia P. A.","year":"2011","journal-title":"Technol. Cancer Res. Treat."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1177\/004051755902901003","volume":"29","author":"Segal L.","year":"1959","journal-title":"Text. Res. J."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.carres.2004.11.027","volume":"340","author":"Oh S. Y.","year":"2005","journal-title":"Carbohydr. Res."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.molcata.2006.03.024","volume":"254","author":"Lex A.","year":"2006","journal-title":"J. Mol. Catal. A: Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"385102","DOI":"10.1088\/0957-4484\/18\/38\/385102","volume":"18","author":"Mohapatra S.","year":"2007","journal-title":"Nanotechnology"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0008-6215(00)81824-8","volume":"30","author":"De Belder A. N.","year":"1973","journal-title":"Carbohydr. Res."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0008-6215(00)84168-3","volume":"44","author":"De Belder A. N.","year":"1975","journal-title":"Carbohydr. Res."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0083-6729(08)00407-X","volume-title":"Folic Acid and Folates","volume":"79","author":"Leamon C. P.","year":"2008"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/bm401593n","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T14:29:02Z","timestamp":1682260142000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/bm401593n"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4,9]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,5,12]]}},"alternative-id":["10.1021\/bm401593n"],"URL":"https:\/\/doi.org\/10.1021\/bm401593n","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,9]]}}}