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Ther."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.cardiores.2003.09.019","volume":"61","author":"Schulz R.","year":"2004","journal-title":"Cardiovasc. Res."},{"key":"ref17\/cit17","first-page":"653","volume":"23","author":"Mellion B. T.","year":"1983","journal-title":"Mol. Pharmacol."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1111\/j.1476-5381.1992.tb14517.x","volume":"107","author":"Radomski M. W.","year":"1992","journal-title":"Br. J. Pharmacol."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1093\/cvr\/28.5.691","volume":"28","author":"de Belder A. J.","year":"1994","journal-title":"Cardiovasc. Res."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S1569-2558(08)60422-1","volume":"18","author":"Radomski M. W.","year":"1997","journal-title":"Adv. Molec. 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