{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T05:05:04Z","timestamp":1773291904140,"version":"3.50.1"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Chem. Biol."],"published-print":{"date-parts":[[2013,5,17]]},"DOI":"10.1021\/cb300374h","type":"journal-article","created":{"date-parts":[[2013,3,15]],"date-time":"2013-03-15T16:55:38Z","timestamp":1363366538000},"page":"914-922","source":"Crossref","is-referenced-by-count":8,"title":["Small Molecule Screen Reveals Regulation of Survival Motor Neuron Protein Abundance by Ras Proteins"],"prefix":"10.1021","volume":"8","author":[{"given":"Reka R.","family":"Letso","sequence":"first","affiliation":[{"name":"Howard\rHughes Medical Institute, Department of Biological Sciences and \u2021Department of\rChemistry, Columbia University, Northwest Corner Building, MC 4846, 550 West 120th Street, New\rYork, New York 10027, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andras J.","family":"Bauer","sequence":"additional","affiliation":[{"name":"Howard\rHughes Medical Institute, Department of Biological Sciences and \u2021Department of\rChemistry, Columbia University, Northwest Corner Building, MC 4846, 550 West 120th Street, New\rYork, New York 10027, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell R.","family":"Lunn","sequence":"additional","affiliation":[{"name":"Howard\rHughes Medical Institute, Department of Biological Sciences and \u2021Department of\rChemistry, Columbia University, Northwest Corner Building, MC 4846, 550 West 120th Street, New\rYork, New York 10027, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan Seok","family":"Yang","sequence":"additional","affiliation":[{"name":"Howard\rHughes Medical Institute, Department of Biological Sciences and \u2021Department of\rChemistry, Columbia University, Northwest Corner Building, MC 4846, 550 West 120th Street, New\rYork, New York 10027, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent R.","family":"Stockwell","sequence":"additional","affiliation":[{"name":"Howard\rHughes Medical Institute, Department of Biological Sciences and \u2021Department of\rChemistry, Columbia University, Northwest Corner Building, MC 4846, 550 West 120th Street, New\rYork, New York 10027, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2013,3,29]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.molcel.2005.12.011","volume":"21","author":"Sopko R.","year":"2006","journal-title":"Mol. Cell"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1080\/09540260902962206","volume":"21","author":"Atmaca M.","year":"2009","journal-title":"Int. Rev. Psychiatry"},{"issue":"8","key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1528-1167.2007.01349.x","volume":"48","author":"Trinka E.","year":"2007","journal-title":"Epilepsia"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1038\/sj.onc.1210204","volume":"26","author":"Marks P. A.","year":"2007","journal-title":"Oncogene"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1177\/107327480301000502","volume":"10","author":"Richardson P. G.","year":"2003","journal-title":"Cancer Control"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/sj.onc.1209793","volume":"26","author":"Sun L.","year":"2007","journal-title":"Oncogene"},{"key":"ref7\/cit7","first-page":"2010","author":"Chateauvieux S.","year":"2010","journal-title":"J. Biomed. Biotechnol."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1093\/hmg\/8.7.1177","volume":"8","author":"Monani U. R.","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/nrn2670","volume":"10","author":"Burghes A. H.","year":"2009","journal-title":"Nat. Rev. Neurosci."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/nchembio.595","volume":"7","author":"Makhortova N. R.","year":"2011","journal-title":"Nat. Chem. Biol."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1093\/hmg\/ddi205","volume":"14","author":"Jarecki J.","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1093\/hmg\/10.24.2841","volume":"10","author":"Andreassi C.","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S1074-5521(99)80004-0","volume":"6","author":"Stockwell B. R.","year":"1999","journal-title":"Chem. Biol."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.chembiol.2003.08.009","volume":"10","author":"Root D. E.","year":"2003","journal-title":"Chem. Biol."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1177\/108705719900400206","volume":"4","author":"Zhang J. H.","year":"1999","journal-title":"J. Biomol. Screening"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.chembiol.2004.08.026","volume":"11","author":"Kelley B. P.","year":"2004","journal-title":"Chem. Biol."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1021\/ci010127n","volume":"42","author":"Rose K.","year":"2002","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1021\/ci990307l","volume":"39","author":"Wildman S. A.","year":"1999","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1093\/hmg\/6.8.1205","volume":"6","author":"Coovert D. D.","year":"1997","journal-title":"Hum. Mol. Genet."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1016\/S0140-6736(08)60921-6","volume":"371","author":"Lunn M. R.","year":"2008","journal-title":"Lancet"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"19925","DOI":"10.1074\/jbc.273.32.19925","volume":"273","author":"Vojtek A. B.","year":"1998","journal-title":"J. Biol. Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/22780","volume":"400","author":"Hahn W. C.","year":"1999","journal-title":"Nature"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.1093\/hmg\/ddp352","volume":"18","author":"Farooq F.","year":"2009","journal-title":"Hum. Mol. Genet."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1128\/MCB.01262-08","volume":"29","author":"Burnett B. G.","year":"2009","journal-title":"Mol. Cell. Biol."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1101\/gad.1884910","volume":"24","author":"Cho S.","year":"2010","journal-title":"Genes Dev."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1126\/science.1177585","volume":"326","author":"Wolan D. W.","year":"2009","journal-title":"Science"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"4955","DOI":"10.1016\/j.febslet.2007.09.031","volume":"581","author":"Huang L.","year":"2007","journal-title":"FEBS Lett."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.chembiol.2009.12.016","volume":"17","author":"Grimm C.","year":"2010","journal-title":"Chem. Biol."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"e4236","DOI":"10.1371\/journal.pone.0004236","volume":"4","author":"Mruk K.","year":"2009","journal-title":"PLoS One"},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1146\/annurev.pharmtox.43.100901.135823","volume":"43","author":"Small K. M.","year":"2003","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/nrd892","volume":"1","author":"Hopkins A. L.","year":"2002","journal-title":"Nat. Rev. Drug Discovery"},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1750-1172-2-30","volume":"2","author":"Segalat L.","year":"2007","journal-title":"Orphanet J. Rare Dis."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/S0092-8674(00)81632-3","volume":"95","author":"Pellizzoni L.","year":"1998","journal-title":"Cell"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1083\/jcb.200304128","volume":"163","author":"Rossoll W.","year":"2003","journal-title":"J. Cell Biol."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/ng0797-265","volume":"16","author":"Lefebvre S.","year":"1997","journal-title":"Nat. Genet."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.cell.2009.01.042","volume":"136","author":"Sonenberg N.","year":"2009","journal-title":"Cell"},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1146\/annurev.ne.19.030196.002335","volume":"19","author":"Segal R. A.","year":"1996","journal-title":"Annu. Rev. Neurosci."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/0896-6273(89)90233-X","volume":"2","author":"Borasio G. D.","year":"1989","journal-title":"Neuron"},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1083\/jcb.151.7.1537","volume":"151","author":"Heumann R.","year":"2000","journal-title":"J. Cell Biol."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1021\/ci990423o","volume":"39","author":"Hann M.","year":"1999","journal-title":"J. Chem. Inf. Comput. Sci."}],"container-title":["ACS Chemical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/cb300374h","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T19:16:20Z","timestamp":1682190980000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/cb300374h"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,29]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5,17]]}},"alternative-id":["10.1021\/cb300374h"],"URL":"https:\/\/doi.org\/10.1021\/cb300374h","relation":{},"ISSN":["1554-8929","1554-8937"],"issn-type":[{"value":"1554-8929","type":"print"},{"value":"1554-8937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,29]]}}}