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Chem."},{"key":"ref13\/cit13a","unstructured":"aHayes, B. L.Microwave Synthesis: Chemistry at the Speed of Light;CEM Publishing:Mathews, NC, 2002; pp29\u221236."},{"key":"ref13\/cit13b","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1039\/b601452f","volume":"8","author":"Gellis A.","year":"2006","journal-title":"Green Chem."},{"key":"ref14\/cit14a","doi-asserted-by":"crossref","first-page":"5323","DOI":"10.1002\/chem.200400597","volume":"10","author":"Ramachary D. B.","year":"2004","journal-title":"Chem.\u2014Eur. J."},{"key":"ref14\/cit14b","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1002\/anie.200351916","volume":"42","author":"Ramachary D. B.","year":"2003","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref15\/cit15a","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1080\/00397919008051547","volume":"20","author":"Villemin D.","year":"1990","journal-title":"Synth. 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