{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T16:52:47Z","timestamp":1790527967176,"version":"4.1.0"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Comb. Chem."],"published-print":{"date-parts":[[2010,1,11]]},"DOI":"10.1021\/cc900157w","type":"journal-article","created":{"date-parts":[[2009,11,30]],"date-time":"2009-11-30T15:13:27Z","timestamp":1259594007000},"page":"206-214","source":"Crossref","is-referenced-by-count":75,"title":["Use of Cyclohexylisocyanide and Methyl 2-Isocyanoacetate as Convertible Isocyanides for Microwave-Assisted Fluorous Synthesis of 1,4-Benzodiazepine-2,5-dione Library"],"prefix":"10.1021","volume":"12","author":[{"given":"Hongyu","family":"Zhou","sequence":"first","affiliation":[{"name":"St. Jude Children\u2019s Research Hospital, Memphis, Tennessee 38105, School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, China, and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, Massachusetts 02125"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"St. Jude Children\u2019s Research Hospital, Memphis, Tennessee 38105, School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, China, and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, Massachusetts 02125"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Yan","sequence":"additional","affiliation":[{"name":"St. Jude Children\u2019s Research Hospital, Memphis, Tennessee 38105, School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, China, and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, Massachusetts 02125"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2009,11,30]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1021\/jm00056a008","volume":"36","author":"Ananthan S.","year":"1993","journal-title":"J. Med. Chem."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"4730","DOI":"10.1021\/jm8002944","volume":"51","author":"Anzini M.","year":"2008","journal-title":"J. Med. Chem."},{"key":"ref3\/cit3","first-page":"9152S","volume":"11","author":"Leonard K.","year":"2005","journal-title":"Clin. Cancer Res."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1016\/j.bmcl.2006.03.067","volume":"16","author":"Marugan J. J.","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1021\/cc030034d","volume":"6","author":"Cheng M. F.","year":"2004","journal-title":"J. Comb. Chem."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"14475","DOI":"10.1021\/ja047472o","volume":"126","author":"Cuny G.","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"3423","DOI":"10.1016\/j.tetlet.2006.03.069","volume":"47","author":"Kalinski C.","year":"2006","journal-title":"Tetrahedron Lett."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1021\/ol0256015","volume":"4","author":"Kennedy A. L.","year":"2002","journal-title":"Org. Lett."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1021\/ol7029799","volume":"10","author":"Salcedo A.","year":"2008","journal-title":"Org. Lett."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"4963","DOI":"10.1016\/S0040-4039(01)00920-0","volume":"42","author":"Tempest P.","year":"2001","journal-title":"Tetrahedron Lett."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1016\/S0040-4039(03)00084-4","volume":"44","author":"Tempest P.","year":"2003","journal-title":"Tetrahedron Lett."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1016\/j.tetlet.2005.01.063","volume":"46","author":"Vasudevan A.","year":"2005","journal-title":"Tetrahedron Lett."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1021\/ar9502083","volume":"29","author":"Armstrong R. W.","year":"1996","journal-title":"Acc. Chem. Res."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1021\/cr0505728","volume":"106","author":"Domling A.","year":"2006","journal-title":"Chem. Rev."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0076-6879(03)69024-5","volume":"369","author":"Hulme C.","year":"2003","journal-title":"Methods Enzymol."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1021\/jo9622845","volume":"62","author":"Boojamra C. G.","year":"1997","journal-title":"J. Org. Chem."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1021\/cc020100w","volume":"5","author":"Ettmayer P.","year":"2003","journal-title":"J. Comb. Chem."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/S0040-4039(99)02326-6","volume":"41","author":"Hulme C.","year":"2000","journal-title":"Tetrahedron Lett."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1021\/cc800085d","volume":"10","author":"Verdie P.","year":"2008","journal-title":"J. Comb. Chem."},{"key":"ref20\/cit20","first-page":"205","author":"Xie H. W.","year":"2009","journal-title":"Synthesis-Stuttgart"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1021\/cc900109e","volume":"11","author":"Liu A. F.","year":"2009","journal-title":"J. Comb. Chem."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"8935","DOI":"10.1021\/jo961517p","volume":"61","author":"Keating T. A.","year":"1996","journal-title":"J. Org. Chem."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"2574","DOI":"10.1021\/ja953868b","volume":"118","author":"Keating T. A.","year":"1996","journal-title":"J. Am. Chem. Soc."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1021\/jm049137g","volume":"48","author":"Grasberger B. L.","year":"2005","journal-title":"J. Med. Chem."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"8021","DOI":"10.1021\/jo980622r","volume":"63","author":"Hulme C.","year":"1998","journal-title":"J. Org. Chem."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.bmcl.2004.11.009","volume":"15","author":"Parks D. J.","year":"2005","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"3310","DOI":"10.1016\/j.bmcl.2006.03.055","volume":"16","author":"Parks D. J.","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"11772","DOI":"10.1021\/ja0644374","volume":"128","author":"Pirrung M. C.","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"5121","DOI":"10.1016\/S0040-4039(03)01119-5","volume":"44","author":"Portlock D. E.","year":"2003","journal-title":"Tetrahedron Lett."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"4110","DOI":"10.1021\/jo900414n","volume":"74","author":"Pirrung M. C.","year":"2009","journal-title":"J. Org. Chem."},{"key":"ref31\/cit31","first-page":"1553","author":"Faggi C.","year":"2003","journal-title":"Synthesis-Stuttgart"},{"key":"ref32\/cit32","first-page":"2756","author":"Faggi C.","year":"2002","journal-title":"Synthesis-Stuttgart"},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"5295","DOI":"10.1016\/S0040-4039(99)00960-0","volume":"40","author":"Hulme C.","year":"1999","journal-title":"Tetrahedron Lett."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.tetlet.2005.01.117","volume":"46","author":"Zhang W.","year":"2005","journal-title":"Tetrahedron Lett."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1021\/ol0496428","volume":"6","author":"Zhang W.","year":"2004","journal-title":"Org. Lett."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.1016\/j.tetlet.2004.04.115","volume":"45","author":"Zhang W.","year":"2004","journal-title":"Tetrahedron Lett."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1021\/cc700164u","volume":"10","author":"Zhou H. Y.","year":"2008","journal-title":"J. Comb. Chem."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1002\/ejoc.200700142","author":"Egger M.","year":"2007","journal-title":"Eur. J. Org. Chem."},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1016\/S0960-894X(03)00626-7","volume":"13","author":"Furet P.","year":"2003","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1021\/ja952220w","volume":"118","author":"Tanaka F.","year":"1996","journal-title":"J. Am. Chem. Soc."}],"container-title":["Journal of Combinatorial Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/cc900157w","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T02:44:23Z","timestamp":1627613063000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/cc900157w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11,30]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1,11]]}},"alternative-id":["10.1021\/cc900157w"],"URL":"https:\/\/doi.org\/10.1021\/cc900157w","relation":{},"ISSN":["1520-4766","1520-4774"],"issn-type":[{"value":"1520-4766","type":"print"},{"value":"1520-4774","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11,30]]}}}