{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T11:41:59Z","timestamp":1769600519244,"version":"3.49.0"},"reference-count":33,"publisher":"American Chemical Society (ACS)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Chem. Neurosci."],"published-print":{"date-parts":[[2012,1,18]]},"DOI":"10.1021\/cn200085z","type":"journal-article","created":{"date-parts":[[2011,10,18]],"date-time":"2011-10-18T17:08:20Z","timestamp":1318957700000},"page":"5-11","source":"Crossref","is-referenced-by-count":32,"title":["Identification of a Maleimide-Based Glycogen Synthase Kinase-3 (GSK-3) Inhibitor, BIP-135, That Prolongs the Median Survival Time of \u03947 SMA KO Mouse Model of Spinal Muscular Atrophy"],"prefix":"10.1021","volume":"3","author":[{"given":"Po C.","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Medicinal Chemistry\rand Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago,\rIllinois 60612, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina N.","family":"Gaisina","sequence":"additional","affiliation":[{"name":"Department of Medicinal Chemistry\rand Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago,\rIllinois 60612, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bassem F.","family":"El-Khodor","sequence":"additional","affiliation":[{"name":"PsychoGenics Inc., 765 Old Sawmill River\rRoad, Tarrytown, New York 10591, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Ramboz","sequence":"additional","affiliation":[{"name":"PsychoGenics Inc., 765 Old Sawmill River\rRoad, Tarrytown, New York 10591, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina R.","family":"Makhortova","sequence":"additional","affiliation":[{"name":"Department of Stem Cell and Regenerative\rBiology and Harvard Stem Cell Institute, Harvard University, 7 Divinity Avenue, Cambridge, Massachusetts 02138, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee L.","family":"Rubin","sequence":"additional","affiliation":[{"name":"Department of Stem Cell and Regenerative\rBiology and Harvard Stem Cell Institute, Harvard University, 7 Divinity Avenue, Cambridge, Massachusetts 02138, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan P.","family":"Kozikowski","sequence":"additional","affiliation":[{"name":"Department of Medicinal Chemistry\rand Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago,\rIllinois 60612, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2011,10,26]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1038\/nrd1415","volume":"3","author":"Cohen P.","year":"2004","journal-title":"Nat. Rev. Drug Discovery"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/35096075","volume":"2","author":"Cohen P.","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"2431","DOI":"10.1002\/j.1460-2075.1990.tb07419.x","volume":"9","author":"Woodgett J. R.","year":"1990","journal-title":"EMBO J."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1038\/sj.npp.1300731","volume":"30","author":"Gould T. D.","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1080\/07853890701483270","volume":"39","author":"Tanis K. Q.","year":"2007","journal-title":"Ann. Med."},{"key":"ref6\/cit6","first-page":"1","volume":"4","author":"Chuang D.-M.","year":"2011","journal-title":"Front. Mol. Neurosci."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1038\/nrd2959","volume":"8","author":"Brunden K. R.","year":"2009","journal-title":"Nat. Rev. Drug Discovery"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1038\/nrd2999","volume":"8","author":"Chico L. K.","year":"2009","journal-title":"Nat Rev Drug Discovery"},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1460-9568.2005.04191.x","volume":"22","author":"Koh S. H.","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.expneurol.2007.03.004","volume":"205","author":"Koh S. H.","year":"2007","journal-title":"Exp. Neurol."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.nurx.2006.01.010","volume":"3","author":"Sumner C. J.","year":"2006","journal-title":"NeuroRx"},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.nurt.2008.08.007","volume":"5","author":"Oskoui M.","year":"2008","journal-title":"Neurotherapeutics"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1038\/nchembio.595","volume":"7","author":"Makhortova N. R.","year":"2011","journal-title":"Nat. Chem. Biol."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.tips.2004.07.006","volume":"25","author":"Meijer L.","year":"2004","journal-title":"Trends Phamacol. Sci."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1021\/jm801317h","volume":"52","author":"Gaisina I. N.","year":"2009","journal-title":"J. Med. Chem."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"8328","DOI":"10.1021\/ja068969w","volume":"129","author":"Kozikowski A. P.","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1002\/cmdc.200500039","volume":"1","author":"Kozikowski A. P.","year":"2006","journal-title":"ChemMedChem"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/jnr.21850","volume":"87","author":"LaPointe N. E.","year":"2009","journal-title":"J. Neurosci. Res."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"5781","DOI":"10.1016\/j.bmc.2006.05.033","volume":"14","author":"Tanaka M.","year":"2006","journal-title":"Bioorg. Med. Chem."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1385\/CBB:45:3:303","volume":"45","author":"Mercer S. E.","year":"2006","journal-title":"Cell Biochem. Biophys."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1741-7015-7-14","volume":"7","author":"Millino C.","year":"2009","journal-title":"BMC Med."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/S0387-7604(02)00103-1","volume":"24","author":"Hayashi M.","year":"2002","journal-title":"Brain Dev."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1046\/j.1471-4159.1994.62010376.x","volume":"62","author":"Ratan R. R.","year":"1994","journal-title":"J. Neurochem."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/nrd1330","volume":"3","author":"Barnham K. J.","year":"2004","journal-title":"Nat. Rev. Drug Discovery"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"2748","DOI":"10.1002\/jnr.22106","volume":"87","author":"Acsadi G.","year":"2009","journal-title":"J. Neurosci. Res."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1523\/JNEUROSCI.3200-07.2008","volume":"28","author":"Langley B.","year":"2008","journal-title":"J. Neurosci."},{"key":"ref27\/cit27","first-page":"161","volume":"1","author":"Natasha G.","year":"2008","journal-title":"Mol. Med. Rep."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1007\/s00109-008-0388-1","volume":"86","author":"Tsai L. K.","year":"2008","journal-title":"J. Mol. Med."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1177\/1756285610369026","volume":"3","author":"Sproule D. M.","year":"2010","journal-title":"Ther. Adv. Neurol. Disord."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1093\/hmg\/ddi078","volume":"14","author":"Le T. T.","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.expneurol.2008.02.025","volume":"212","author":"El-Khodor B. F.","year":"2008","journal-title":"Exp. Neurol."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"4239","DOI":"10.1093\/hmg\/ddq343","volume":"19","author":"Gladman J. T.","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"19599","DOI":"10.1073\/pnas.0907935106","volume":"106","author":"Rivieccio M. A.","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["ACS Chemical Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/cn200085z","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,5]],"date-time":"2023-04-05T19:30:08Z","timestamp":1680723008000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/cn200085z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,10,26]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1,18]]}},"alternative-id":["10.1021\/cn200085z"],"URL":"https:\/\/doi.org\/10.1021\/cn200085z","relation":{},"ISSN":["1948-7193","1948-7193"],"issn-type":[{"value":"1948-7193","type":"print"},{"value":"1948-7193","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,10,26]]}}}