{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:15:49Z","timestamp":1792793749489,"version":"4.5.0"},"reference-count":59,"publisher":"American Chemical Society (ACS)","issue":"2","license":[{"start":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:00:00Z","timestamp":1761004800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012582","name":"Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["2023QNXZ05"],"award-info":[{"award-number":["2023QNXZ05"]}],"id":[{"id":"10.13039\/501100012582","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013061","name":"Jilin Provincial Scientific and Technological Development Program","doi-asserted-by":"publisher","award":["YDZJ202301ZYTS227"],"award-info":[{"award-number":["YDZJ202301ZYTS227"]}],"id":[{"id":"10.13039\/501100013061","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42307187"],"award-info":[{"award-number":["42307187"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42377282"],"award-info":[{"award-number":["42377282"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A6001"],"award-info":[{"award-number":["U23A6001"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Health"],"published-print":{"date-parts":[[2026,2,20]]},"DOI":"10.1021\/envhealth.5c00170","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T14:41:16Z","timestamp":1761057676000},"page":"313-323","source":"Crossref","is-referenced-by-count":12,"title":["Microplastics and Nanoplastics Cause Thyroid Dysfunction in Adolescent Mice through the Intestinal Microbiota-Mediated Hypothalamus-Pituitary-Thyroid Axis"],"prefix":"10.1021","volume":"4","author":[{"given":"Jinpeng","family":"Zhang","sequence":"first","affiliation":[{"name":"Research Center of Regional Development and Environment","place":["Changchun, China"]},{"name":"Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences","place":["Changchun, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaoyang","family":"Ji","sequence":"additional","affiliation":[{"name":"Research Center of Regional Development and Environment","place":["Changchun, China"]},{"name":"Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences","place":["Changchun, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaowei","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Reproductive Medicine Center","place":["Changchun, China"]},{"name":"The Second Norman Bethune Hospital of Jilin University","place":["Changchun, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Endocrinology","place":["Tianjin, China"]},{"name":"Tianjin Huanghe Hospital","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Research Center of Regional Development and Environment","place":["Changchun, China"]},{"name":"Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences","place":["Changchun, China"]},{"name":"College of Horticulture","place":["Changchun, China"]},{"name":"Jilin Agricultural University","place":["Changchun, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoxuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Animal Sciences","place":["Changchun, China"]},{"name":"Jilin University","place":["Changchun, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6903-2367","authenticated-orcid":true,"given":"Yong","family":"Yu","sequence":"additional","affiliation":[{"name":"Research Center of Regional Development and Environment","place":["Changchun, China"]},{"name":"Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences","place":["Changchun, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,10,21]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b04535"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2018.01.024"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.4c00351"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.3c06668"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.176228"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c02407"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.3c09756"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2024.134960"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2025.125754"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.abn6875"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1126\/science.abg5645"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-56979-4"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-95005-x"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-023-01525-x"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3196"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-019-0231-1"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41417-024-00833-0"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.aninu.2024.05.001"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-024-01108-6"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-06466-x"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.4c00267"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-56375-y"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.2c04888"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-67881-2"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.903316"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2020.11.015"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2022.107199"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c07933"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.168421"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2017.47"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.eprac.2025.02.004"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00604-6"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03634-7"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-024-01873-w"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2025.126242"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.thscie.2025.100025"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-85693-w"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2024.124103"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-50548-x"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2024.153883"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01954-21"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-74379-0"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.03144-23"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5c00817"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c00573"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(88)90003-9"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.joim.2024.06.004"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(95)02525-2"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2024.107972"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-024-01827-7"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-48220-5"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2025.110352"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.136817"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2023.115411"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-022-00646-6"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1007\/s13317-016-0090-1"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-49824-7"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2300582121"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.3c01942"}],"container-title":["Environment & Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/envhealth.5c00170","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/envhealth.5c00170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T08:54:11Z","timestamp":1773132851000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/envhealth.5c00170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,21]]},"references-count":59,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2,20]]}},"alternative-id":["10.1021\/envhealth.5c00170"],"URL":"https:\/\/doi.org\/10.1021\/envhealth.5c00170","relation":{},"ISSN":["2833-8278","2833-8278"],"issn-type":[{"value":"2833-8278","type":"print"},{"value":"2833-8278","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,21]]}}}