{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:37:36Z","timestamp":1791981456966,"version":"4.4.0"},"reference-count":42,"publisher":"American Chemical Society (ACS)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2003,1,1]]},"DOI":"10.1021\/ja027983f","type":"journal-article","created":{"date-parts":[[2003,1,22]],"date-time":"2003-01-22T06:52:54Z","timestamp":1043218374000},"page":"940-950","source":"Crossref","is-referenced-by-count":66,"title":["Solid-Phase Chemical Synthesis of Phosphonoacetate and Thiophosphonoacetate Oligodeoxynucleotides"],"prefix":"10.1021","volume":"125","author":[{"given":"Douglas J.","family":"Dellinger","sequence":"first","affiliation":[{"name":"Contribution from the Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215 and MetaSense Technologies, Des Moines, Iowa 50322"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Sheehan","sequence":"additional","affiliation":[{"name":"Contribution from the Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215 and MetaSense Technologies, Des Moines, Iowa 50322"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanna K.","family":"Christensen","sequence":"additional","affiliation":[{"name":"Contribution from the Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215 and MetaSense Technologies, Des Moines, Iowa 50322"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James G.","family":"Lindberg","sequence":"additional","affiliation":[{"name":"Contribution from the Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215 and MetaSense Technologies, Des Moines, Iowa 50322"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marvin H.","family":"Caruthers","sequence":"additional","affiliation":[{"name":"Contribution from the Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215 and MetaSense Technologies, Des Moines, Iowa 50322"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2003,1,3]]},"reference":[{"key":"ja027983fb00001\/ja027983fb00001_1","volume-title":"appropriately protected purine or pyrimidine base","author":"Abbreviations B"},{"key":"ja027983fb00002\/ja027983fb00002_1","first-page":"30","volume":"1489","author":"Bennett C. F.","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"ja027983fb00003\/ja027983fb00003_1","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S1367-5931(98)80129-4","volume":"2","author":"Agrawal S.","year":"1998","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ja027983fb00004\/ja027983fb00004_1","first-page":"867","volume":"18","author":"Zhang H.","year":"2000","journal-title":"Nat. Biotechnol."},{"key":"ja027983fb00005\/ja027983fb00005_1","doi-asserted-by":"crossref","first-page":"8741","DOI":"10.1021\/bi960318x","volume":"35","author":"Cummins L.","year":"1996","journal-title":"Biochemistry"},{"key":"ja027983fb00006\/ja027983fb00006_1","doi-asserted-by":"crossref","first-page":"4564","DOI":"10.1093\/nar\/24.22.4558","volume":"24","author":"Vaughn J. P.","year":"1996","journal-title":"Nucleic Acids Res."},{"key":"ja027983fb00007\/ja027983fb00007_1","volume-title":"CA","author":"Yuen A.","year":"2001"},{"key":"ja027983fb00008\/ja027983fb00008_1","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1126\/science.8351515","volume":"261","author":"Stein C. A.","year":"1993","journal-title":"Science"},{"key":"ja027983fb00009\/ja027983fb00009_1","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1002\/anie.199213731","volume":"31","author":"Tomasz J.","year":"1992","journal-title":"Angew. Chem., Int. Ed. Engl."},{"key":"ja027983fb00010\/ja027983fb00010_1","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.1016\/S0040-4039(98)00687-X","volume":"39","author":"Higson A. P.","year":"1998","journal-title":"Tetrahedron Lett."},{"key":"ja027983fb00011\/ja027983fb00011_1","doi-asserted-by":"crossref","first-page":"9427","DOI":"10.1021\/ja9814927","volume":"120","author":"Sergueev D. S.","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"ja027983fb00012\/ja027983fb00012_1","first-page":"788","volume":"20","author":"Wang J.","year":"2001","journal-title":"Nucleosides Nucleotides"},{"key":"ja027983fb00013\/ja027983fb00013_1","doi-asserted-by":"crossref","first-page":"13545","DOI":"10.1021\/ja985535v","volume":"120","author":"Damha M. J.","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"ja027983fb00014\/ja027983fb00014_1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0958-1669(00)00170-1","volume":"12","author":"Nielsen P. E.","year":"2001","journal-title":"Curr. Opin. Biotechnol."},{"key":"ja027983fb00015\/ja027983fb00015_1","doi-asserted-by":"crossref","first-page":"3630","DOI":"10.1016\/S0040-4020(98)00094-5","volume":"54","author":"Koshkin A. A.","year":"1998","journal-title":"Tetrahedron"},{"key":"ja027983fb00016\/ja027983fb00016_1","first-page":"304","volume":"23","author":"Miller P. S.","year":"1988","journal-title":"Annu. Rep. Med. Chem."},{"key":"ja027983fb00017\/ja027983fb00017_1","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1021\/jm00117a026","volume":"31","author":"Griengl H.","year":"1988","journal-title":"J. Med. Chem."},{"key":"ja027983fb00018\/ja027983fb00018_1","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1021\/jm00122a014","volume":"32","author":"Lambert R. W.","year":"1989","journal-title":"J. Med. Chem."},{"key":"ja027983fb00019\/ja027983fb00019_1","first-page":"1739","volume":"15","author":"Rudolph M. J.","year":"1996","journal-title":"Nucleosides Nucleotides"},{"key":"ja027983fb00020\/ja027983fb00020_1","doi-asserted-by":"crossref","first-page":"3191","DOI":"10.1021\/ja00401a041","volume":"103","author":"Matteucci M. D.","year":"1981","journal-title":"J. Am. Chem. Soc."},{"key":"ja027983fb00021\/ja027983fb00021_1","doi-asserted-by":"crossref","first-page":"6694","DOI":"10.1093\/nar\/10.21.6675","volume":"10","author":"Efimov V. A.","year":"1982","journal-title":"Nucleic Acids Res."},{"key":"ja027983fb00022\/ja027983fb00022_1","first-page":"222","volume":"42","author":"VanDoorn J. A.","year":"1989","journal-title":"Phosphorus, Sulfur Silicon Relat. Elem."},{"key":"ja027983fb00023\/ja027983fb00023_1","first-page":"1700","volume":"42","author":"Matrosov E. I.","year":"1972","journal-title":"Zh. Obshch. Khim."},{"key":"ja027983fb00024\/ja027983fb00024_1","first-page":"72","volume":"43","author":"Podlahova J.","year":"1978","journal-title":"Collect. Czech. Chem. Commun."},{"key":"ja027983fb00025\/ja027983fb00025_1","first-page":"578","volume":"46","author":"Novikova Z. S.","year":"1976","journal-title":"Zh. Obshch. Khim."},{"key":"ja027983fb00026\/ja027983fb00026_1","first-page":"2217","volume":"46","author":"Novikova Z. S.","year":"1976","journal-title":"Zh. Obshch. Khim."},{"key":"ja027983fb00027\/ja027983fb00027_1","first-page":"2390","volume":"49","author":"Stepanov I. A.","year":"1979","journal-title":"Zh. Obshch. Khim."},{"key":"ja027983fb00028\/ja027983fb00028_1","first-page":"128","volume":"18","author":"King R. B.","year":"1983","journal-title":"Phosphorus Sulfur Relat. Elem."},{"key":"ja027983fb00030\/ja027983fb00030_1","first-page":"2392","volume":"46","author":"Malenko D. M.","year":"1976","journal-title":"Yu. G. Zh. Obshch. Khim."},{"key":"ja027983fb00031\/ja027983fb00031_1","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1021\/ja01638a008","volume":"76","author":"Bayles P. L.","year":"1954","journal-title":"J. Am. Chem. Soc."},{"key":"ja027983fb00032\/ja027983fb00032_1","first-page":"2038","volume":"21","author":"Hogrefe R. I.","year":"1993","journal-title":"J. Nucleic Acids Res."},{"key":"ja027983fb00033\/ja027983fb00033_1","first-page":"608","volume":"7","author":"Ugi I.","year":"1988","journal-title":"Nucleosides Nucleotides"},{"key":"ja027983fb00034\/ja027983fb00034_1","doi-asserted-by":"crossref","first-page":"4699","DOI":"10.1021\/jo00302a040","volume":"55","author":"Iyer R. P.","year":"1990","journal-title":"J. Org. Chem."},{"key":"ja027983fb00036\/ja027983fb00036_1","unstructured":"Emsley, J.; Hall, D.The Chemistry of Phosphorus; Harper and Row:\u2009 London, 1976; pp 133\u2212139."},{"key":"ja027983fb00037\/ja027983fb00037_1","doi-asserted-by":"crossref","first-page":"4167","DOI":"10.1021\/jo01309a019","volume":"45","author":"Sekine M.","year":"1980","journal-title":"J. Org. Chem."},{"key":"ja027983fb00038\/ja027983fb00038_1","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1021\/ja00495a018","volume":"101","author":"Narayanan K. S.","year":"1979","journal-title":"J. Am. Chem. Soc."},{"key":"ja027983fb00039\/ja027983fb00039_1","doi-asserted-by":"crossref","first-page":"7388","DOI":"10.1021\/ja00491a041","volume":"100","author":"Kluger R.","year":"1978","journal-title":"J. Am. Chem. Soc."},{"key":"ja027983fb00040\/ja027983fb00040_1","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1021\/ja01462a032","volume":"83","author":"Tener G.","year":"1961","journal-title":"J. Am. Chem. Soc."},{"key":"ja027983fb00041\/ja027983fb00041_1","volume-title":"R.","author":"Caruthers M. H.","year":"1987"},{"key":"ja027983fb00042\/ja027983fb00042_1","unstructured":"The Glen Report,Glen Research Corporation Technical Report, Vol. 9; Glen Research Sterling, VA, 1996; pp 8\u22129."},{"key":"ja027983fb00043\/ja027983fb00043_1","first-page":"4314","volume":"35","author":"Reddy M. P.","year":"1994","journal-title":"Tetrahedron Lett."},{"key":"ja027983fb00045\/ja027983fb00045_1","doi-asserted-by":"crossref","first-page":"5566","DOI":"10.1016\/S0021-9258(19)39397-4","volume":"265","author":"Hogrefe H. H.","year":"1990","journal-title":"J. Biol. Chem."}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ja027983f","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,17]],"date-time":"2021-10-17T22:39:57Z","timestamp":1634510397000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ja027983f"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,1]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,1,1]]}},"alternative-id":["10.1021\/ja027983f"],"URL":"https:\/\/doi.org\/10.1021\/ja027983f","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,1,1]]}}}