{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T09:18:44Z","timestamp":1774689524096,"version":"3.50.1"},"reference-count":33,"publisher":"American Chemical Society (ACS)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2008,1,30]]},"DOI":"10.1021\/ja076557x","type":"journal-article","created":{"date-parts":[[2008,1,4]],"date-time":"2008-01-04T10:01:13Z","timestamp":1199440873000},"page":"1488-1494","source":"Crossref","is-referenced-by-count":20,"title":["Mg<sup>2+<\/sup>-Free <i>Bacillus stearothermophilus<\/i> Tryptophanyl-tRNA Synthetase Retains a Major Fraction of the Overall Rate Enhancement for Tryptophan Activation"],"prefix":"10.1021","volume":"130","author":[{"given":"Violetta","family":"Weinreb","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Biophysics, CB 7260, University of North Carolina, Chapel Hill, North Carolina 27599-7260"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles W.","family":"Carter","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Biophysics, CB 7260, University of North Carolina, Chapel Hill, North Carolina 27599-7260"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2008,1,4]]},"reference":[{"key":"ja076557xb00001\/ja076557xb00001_1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1021\/bi00902a030","volume":"2","author":"Tetas M.","year":"1963","journal-title":"Biochemistry"},{"key":"ja076557xb00002\/ja076557xb00002_1","doi-asserted-by":"crossref","first-page":"11627","DOI":"10.1021\/ja00152a001","volume":"117","author":"Fothergill M.","year":"1995","journal-title":"J. Am. Chem. Soc."},{"key":"ja076557xb00003\/ja076557xb00003_1","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1021\/ja00164a003","volume":"112","author":"\u00c5qvist J.","year":"1990","journal-title":"J. Am. Chem. Soc."},{"key":"ja076557xb00004\/ja076557xb00004_1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1002\/j.1460-2075.1991.tb07917.x","volume":"10","author":"Beese L. S.","year":"1991","journal-title":"EMBO J."},{"key":"ja076557xb00005\/ja076557xb00005_1","doi-asserted-by":"crossref","first-page":"12405","DOI":"10.1021\/bi0011781","volume":"39","author":"Saderholm M. J.","year":"2000","journal-title":"Biochemistry"},{"key":"ja076557xb00006\/ja076557xb00006_1","doi-asserted-by":"crossref","first-page":"7844","DOI":"10.1073\/pnas.82.23.7840","volume":"82","author":"Leatherbarrow R. J.","year":"1985","journal-title":"Proc. Natl. Acad. Sci., U.S.A."},{"key":"ja076557xb00007\/ja076557xb00007_1","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1021\/ja00978a044","volume":"89","author":"Kirby A. J.","year":"1967","journal-title":"J. Am. Chem. Soc."},{"key":"ja076557xb00008\/ja076557xb00008_1","first-page":"1172","volume":"418","author":"Kirby A. J.","year":"1970","journal-title":"J. Chem. Soc."},{"key":"ja076557xb00009\/ja076557xb00009_1","doi-asserted-by":"crossref","first-page":"5043","DOI":"10.1021\/bi00015a014","volume":"34","author":"First E. A.","year":"1995","journal-title":"Biochemistry"},{"key":"ja076557xb00011\/ja076557xb00011_1","first-page":"8037","volume":"26","author":"Fersht A. R.","year":"1987","journal-title":"Biochemistry"},{"key":"ja076557xb00012\/ja076557xb00012_1","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1021\/bi00405a029","volume":"27","author":"Fersht A. R.","year":"1988","journal-title":"Biochemistry"},{"key":"ja076557xb00013\/ja076557xb00013_1","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1016\/j.jmb.2006.06.078","volume":"362","author":"Kapustina M.","year":"2006","journal-title":"J. Mol. Biol."},{"key":"ja076557xb00014\/ja076557xb00014_1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0022-2836(02)01156-7","volume":"325","author":"Retailleau P.","year":"2003","journal-title":"J. Mol. Biol."},{"key":"ja076557xb00015\/ja076557xb00015_1","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jmb.2007.01.091","volume":"369","author":"Retailleau P.","year":"2007","journal-title":"J. Mol. Biol."},{"key":"ja076557xb00016\/ja076557xb00016_1","first-page":"110","volume-title":"The Aminoacyl-tRNA Synthetases","author":"Carter C. W.","year":"2005"},{"key":"ja076557xb00017\/ja076557xb00017_1","first-page":"249","volume":"103","author":"Levitt M.","year":"1976","journal-title":"J. Mol. Biol."},{"key":"ja076557xb00018\/ja076557xb00018_1","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/j.1749-6632.1990.tb37669.x","volume":"603","author":"Cohn M.","year":"1990","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"ja076557xb00019\/ja076557xb00019_1","first-page":"4379","volume":"253","author":"Adolfson R.","year":"1978","journal-title":"J. Biol. Chem."},{"key":"ja076557xb00020\/ja076557xb00020_1","volume-title":"The Handbook - A Guide to Fluorescent Probes and Labeling Technologies","author":"Haugland R. P.","year":"2005"},{"key":"ja076557xb00021\/ja076557xb00021_1","first-page":"12","volume":"158","author":"Holmquist B.","year":"1981","journal-title":"Methods Enzymol."},{"key":"ja076557xb00022\/ja076557xb00022_1","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/1074-5521(95)90101-9","volume":"2","author":"Admiraal S. J.","year":"1995","journal-title":"Chem. Biol."},{"key":"ja076557xb00023\/ja076557xb00023_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0969-2126(01)00132-0","volume":"3","author":"Doublie S.","year":"1995","journal-title":"Structure"},{"key":"ja076557xb00024\/ja076557xb00024_1","first-page":"1608","volume":"57","author":"Retailleau P.","year":"2001","journal-title":"Acta Crystallogr."},{"key":"ja076557xb00025\/ja076557xb00025_1","first-page":"568","volume":"564","author":"Carter P.","year":"1988","journal-title":"Nature"},{"key":"ja076557xb00026\/ja076557xb00026_1","first-page":"229","volume":"1205","author":"Chan K. W.","year":"1994","journal-title":"Biochim. Biophys. Acta"},{"key":"ja076557xb00027\/ja076557xb00027_1","first-page":"36","volume":"363","author":"Chan K. W.","year":"1995","journal-title":"FEBS Lett."},{"key":"ja076557xb00028\/ja076557xb00028_1","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1016\/j.str.2007.08.010","volume":"15","author":"Kapustina M.","year":"2007","journal-title":"Structure"},{"key":"ja076557xb00029\/ja076557xb00029_1","first-page":"862","volume":"25","author":"Pham Y.","year":"2006","journal-title":"Mol. Cell"},{"key":"ja076557xb00030\/ja076557xb00030_1","volume-title":"Stability Constants of Metal Ion Complexes","author":"Sillen L. G.","year":"1964"},{"key":"ja076557xb00031\/ja076557xb00031_1","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.ceca.2003.10.006","volume":"35","author":"Patton C.","year":"2004","journal-title":"Cell Calcium"},{"key":"ja076557xb00032\/ja076557xb00032_1","volume-title":"WA, 2002.","author":"Microsoft Excel","year":"2002"},{"key":"ja076557xb00033\/ja076557xb00033_1","unstructured":"SAS, V.6 ed.; SAS:\u2009 Cary, NC, 2004."},{"key":"ja076557xb00034\/ja076557xb00034_1","unstructured":"Synergy, 4.01 ed.; Synergy Software:\u2009 Reading, PA, 2005."}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ja076557x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,6]],"date-time":"2021-10-06T02:04:15Z","timestamp":1633485855000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ja076557x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1,4]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,1,30]]}},"alternative-id":["10.1021\/ja076557x"],"URL":"https:\/\/doi.org\/10.1021\/ja076557x","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,1,4]]}}}