{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T03:42:07Z","timestamp":1792208527260,"version":"4.4.0"},"reference-count":38,"publisher":"American Chemical Society (ACS)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2013,3,27]]},"DOI":"10.1021\/ja312221g","type":"journal-article","created":{"date-parts":[[2013,3,15]],"date-time":"2013-03-15T17:18:10Z","timestamp":1363367890000},"page":"4799-4804","source":"Crossref","is-referenced-by-count":497,"title":["Multifunctional Mesoporous Silica-Coated Graphene Nanosheet Used for Chemo-Photothermal Synergistic Targeted Therapy of Glioma"],"prefix":"10.1021","volume":"135","author":[{"given":"Yi","family":"Wang","sequence":"first","affiliation":[{"name":"Center of Analysis\rand Measurement, Fudan University, Shanghai 200433, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiyuan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin\r150040, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfeng","family":"Zhao","sequence":"additional","affiliation":[{"name":"Center of Analysis\rand Measurement, Fudan University, Shanghai 200433, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingang","family":"Liu","sequence":"additional","affiliation":[{"name":"Center of Analysis\rand Measurement, Fudan University, Shanghai 200433, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Bu","sequence":"additional","affiliation":[{"name":"Department of Macromolecular\rScience, State Key Laboratory of Molecular Engineering\rof Polymers, Fudan University, Shanghai\r200433, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueying","family":"Yan","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin\r150040, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongqin","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, School of Pharmacy, Key Laboratory of Smart Drug Delivery, Ministry\rof Education and PLA, Fudan University,\rShanghai 201203, China"},{"name":"Department of Macromolecular\rScience, State Key Laboratory of Molecular Engineering\rof Polymers, Fudan University, Shanghai\r200433, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2013,3,15]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/nrc2818","volume":"10","author":"Huse J. T.","year":"2010","journal-title":"Nat. Rev. Cancer."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1038\/nrclinonc.2010.98","volume":"7","author":"Morris P. G.","year":"2010","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1038\/ncponc1204","volume":"5","author":"Sorensen A. G.","year":"2008","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"10876","DOI":"10.1021\/ja803688x","volume":"130","author":"Liu Z.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.1021\/nn200021j","volume":"5","author":"Hu W.","year":"2011","journal-title":"ACS Nano"},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1002\/smll.201100191","volume":"7","author":"Bao H.","year":"2011","journal-title":"Small"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1002\/adma.201104070","volume":"24","author":"Hu S. H.","year":"2012","journal-title":"Adv. Mater."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"6825","DOI":"10.1021\/ja2010175","volume":"133","author":"Robinson J. T.","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"3318","DOI":"10.1021\/nl100996u","volume":"10","author":"Yang K.","year":"2010","journal-title":"Nano Lett."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1002\/adma.201104864","volume":"24","author":"Li M.","year":"2012","journal-title":"Adv. Mater."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nnano.2007.451","volume":"3","author":"Li D.","year":"2008","journal-title":"Nat. Nanotechnol."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1126\/science.1150878","volume":"319","author":"Li X. L.","year":"2008","journal-title":"Science"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"7437","DOI":"10.1021\/nn102618n","volume":"4","author":"Wang Z. M.","year":"2010","journal-title":"ACS Nano"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/nnano.2008.34","volume":"3","author":"Tasciotti E.","year":"2008","journal-title":"Nat. Nanotechnol."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"14608","DOI":"10.1039\/c2jm32398b","volume":"22","author":"Wang Y.","year":"2012","journal-title":"J. Mater. Chem."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1021\/bm101206g","volume":"12","author":"Wang J.","year":"2011","journal-title":"Biomacromolecules"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.1016\/j.biomaterials.2010.11.079","volume":"32","author":"Huang R. Q.","year":"2011","journal-title":"Biomaterials"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"18143","DOI":"10.1073\/pnas.1003919107","volume":"107","author":"Ding H.","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U S A."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1038\/nbt0598-449","volume":"16","author":"Debinski W.","year":"1998","journal-title":"Nat. Biotechnol."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1158\/1535-7163.MCT-08-0853","volume":"8","author":"Madhankumar A. B.","year":"2009","journal-title":"Mol. Cancer. Ther."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1021\/ja01539a017","volume":"80","author":"Hummers W. S. J.","year":"1958","journal-title":"J. Am. Chem. Soc."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/nnano.2008.365","volume":"4","author":"Choucair M.","year":"2009","journal-title":"Nat. Nanotechnol."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"4490","DOI":"10.1002\/adma.200801306","volume":"20","author":"Fan X. B.","year":"2008","journal-title":"Adv. Mater."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s12274-008-8021-8","volume":"1","author":"Sun X.","year":"2008","journal-title":"Nano Res."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/j.biomaterials.2010.10.030","volume":"32","author":"Markovic Z. M.","year":"2011","journal-title":"Biomaterials"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1002\/smll.201200217","volume":"8","author":"Zhu J.","year":"2012","journal-title":"Small"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1002\/adma.201104714","volume":"24","author":"Zhang Z.","year":"2012","journal-title":"Adv. Mater."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1021\/mp100221h","volume":"7","author":"Mok H.","year":"2010","journal-title":"Mol. Pharmaceutics"},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"17627","DOI":"10.1073\/pnas.1211714109","volume":"109","author":"Padilla-Parra S.","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U S A."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"4907","DOI":"10.1016\/j.biomaterials.2012.03.031","volume":"33","author":"Liu S. H.","year":"2012","journal-title":"Biomaterials"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1021\/tx200339h","volume":"25","author":"Sanchez V. C.","year":"2012","journal-title":"Chem. Res. Toxicol."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"7785","DOI":"10.1016\/j.biomaterials.2010.07.008","volume":"31","author":"He Q.","year":"2010","journal-title":"Biomaterials"},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"4987","DOI":"10.1021\/nn201092p","volume":"5","author":"Singh S. K.","year":"2011","journal-title":"ACS Nano"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1021\/nn1024303","volume":"5","author":"Yang K.","year":"2011","journal-title":"ACS Nano"},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1021\/nn300172t","volume":"6","author":"Singh S. K.","year":"2012","journal-title":"ACS Nano"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1039\/C2CS35342C","volume":"42","author":"Yang K.","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"6116","DOI":"10.1158\/0008-5472.CAN-10-4557","volume":"71","author":"Lu W.","year":"2011","journal-title":"Cancer Res."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.2217\/nnm.11.189","volume":"7","author":"Day E. S.","year":"2012","journal-title":"Nanomedicine"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ja312221g","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T15:08:32Z","timestamp":1682262512000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ja312221g"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,15]]},"references-count":38,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,3,27]]}},"alternative-id":["10.1021\/ja312221g"],"URL":"https:\/\/doi.org\/10.1021\/ja312221g","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,15]]}}}