{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:27:17Z","timestamp":1791203237930,"version":"4.2.0"},"reference-count":62,"publisher":"American Chemical Society (ACS)","issue":"36","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2013,9,11]]},"DOI":"10.1021\/ja404714a","type":"journal-article","created":{"date-parts":[[2013,8,26]],"date-time":"2013-08-26T14:15:58Z","timestamp":1377526558000},"page":"13414-13424","source":"Crossref","is-referenced-by-count":68,"title":["Mimicry of High-Density Lipoprotein: Functional Peptide\u2013Lipid Nanoparticles Based on Multivalent Peptide Constructs"],"prefix":"10.1021","volume":"135","author":[{"given":"Yannan","family":"Zhao","sequence":"first","affiliation":[{"name":"Department\rof Chemistry, \u2021Department of Immunology and Microbial Science, and \u00a7The Skaggs Institute\rfor Chemical Biology, The Scripps Research Institute, 10550 North\rTorrey Pines Road, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Imura","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, \u2021Department of Immunology and Microbial Science, and \u00a7The Skaggs Institute\rfor Chemical Biology, The Scripps Research Institute, 10550 North\rTorrey Pines Road, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke J.","family":"Leman","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, \u2021Department of Immunology and Microbial Science, and \u00a7The Skaggs Institute\rfor Chemical Biology, The Scripps Research Institute, 10550 North\rTorrey Pines Road, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda K.","family":"Curtiss","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, \u2021Department of Immunology and Microbial Science, and \u00a7The Skaggs Institute\rfor Chemical Biology, The Scripps Research Institute, 10550 North\rTorrey Pines Road, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce E.","family":"Maryanoff","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, \u2021Department of Immunology and Microbial Science, and \u00a7The Skaggs Institute\rfor Chemical Biology, The Scripps Research Institute, 10550 North\rTorrey Pines Road, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Reza","family":"Ghadiri","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, \u2021Department of Immunology and Microbial Science, and \u00a7The Skaggs Institute\rfor Chemical Biology, The Scripps Research Institute, 10550 North\rTorrey Pines Road, La Jolla, California 92037, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2013,8,26]]},"reference":[{"key":"ref1\/cit1a","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1021\/ja808856z","volume":"131","author":"Thaxton C. S.","year":"2009","journal-title":"J. Am. Chem. Soc."},{"key":"ref1\/cit1b","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.molmed.2010.10.006","volume":"16","author":"Luthi A. J.","year":"2010","journal-title":"Trends Mol. Med."},{"key":"ref1\/cit1c","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1021\/nn103098m","volume":"5","author":"Bricarello D. A.","year":"2011","journal-title":"ACS Nano"},{"key":"ref1\/cit1d","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1021\/nn2035457","volume":"6","author":"Luthi A. J.","year":"2012","journal-title":"ACS Nano"},{"key":"ref2\/cit2a","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/MOL.0b013e328338472d","volume":"21","author":"Rothblat G. H.","year":"2010","journal-title":"Curr. Opin. Lipidol."},{"key":"ref2\/cit2b","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/MOL.0b013e3283468061","volume":"22","author":"Asztalos B. F.","year":"2011","journal-title":"Curr. Opin. Lipidol."},{"key":"ref2\/cit2c","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1373\/clinchem.2010.155333","volume":"57","author":"Rosenson R. S.","year":"2011","journal-title":"Clin. Chem."},{"key":"ref3\/cit3a","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4419-1059-2","volume-title":"High Density Lipoproteins, Dyslipidemia, and Coronary Heart Disease","author":"Schaefer E. J.","year":"2010"},{"key":"ref3\/cit3b","volume-title":"High-Density Lipoproteins. Structure, Metabolism, Function and Therapeutics","author":"Kontush A.","year":"2012"},{"key":"ref4\/cit4a","doi-asserted-by":"crossref","first-page":"4134","DOI":"10.2174\/138161210794519228","volume":"16","author":"Murphy A. J.","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"ref4\/cit4b","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.2174\/138161210791050988","volume":"16","author":"Spillmann F.","year":"2010","journal-title":"Curr. Pharm. Des."},{"key":"ref4\/cit4c","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.jacl.2010.08.018","volume":"4","author":"Tardif J.-C.","year":"2010","journal-title":"J. Clin. Lipidol."},{"key":"ref5\/cit5a","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1007\/s11883-009-0008-8","volume":"11","author":"Van Lenten B. J.","year":"2009","journal-title":"Curr. Atheroscler. Rep."},{"key":"ref5\/cit5b","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/s11883-010-0097-4","volume":"12","author":"Getz G. S.","year":"2010","journal-title":"Curr. Atheroscler. Rep."},{"key":"ref5\/cit5c","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/MOL.0b013e3283404507","volume":"21","author":"Hovingh G.","year":"2010","journal-title":"Curr. Opin. Lipidol."},{"key":"ref5\/cit5d","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.pharmthera.2010.12.003","volume":"130","author":"Osei-Hwedieh D. O.","year":"2011","journal-title":"Pharmacol. Ther."},{"key":"ref5\/cit5e","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/MED.0b013e32835056d4","volume":"19","author":"Gordon S. M.","year":"2012","journal-title":"Curr. Opin. Endocrinol. Diabetes Obes."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S0022-2275(20)32028-9","volume":"41","author":"Frank P. G.","year":"2000","journal-title":"J. Lipid Res."},{"key":"ref7\/cit7a","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1074\/jbc.270.4.1602","volume":"270","author":"Mishra V. K.","year":"1995","journal-title":"J. Biol. Chem."},{"key":"ref7\/cit7b","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1432-1033.1996.0074u.x","volume":"239","author":"Demoor L.","year":"1996","journal-title":"Eur. J. Biochem."},{"key":"ref7\/cit7c","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0021-9150(98)00176-2","volume":"141","author":"Nion S.","year":"1998","journal-title":"Atherosclerosis"},{"key":"ref7\/cit7d","doi-asserted-by":"crossref","first-page":"32273","DOI":"10.1074\/jbc.M804461200","volume":"283","author":"Sethi A. A.","year":"2008","journal-title":"J. Biol. Chem."},{"key":"ref7\/cit7e","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1194\/jlr.M700552-JLR200","volume":"49","author":"Wool G. D.","year":"2008","journal-title":"J. Lipid Res."},{"key":"ref7\/cit7f","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1194\/jlr.M900151-JLR200","volume":"50","author":"Wool G. D.","year":"2009","journal-title":"J. Lipid Res."},{"key":"ref7\/cit7g","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1161\/CIRCRESAHA.110.216507","volume":"107","author":"D\u2019Souza W.","year":"2010","journal-title":"Circ. Res."},{"key":"ref7\/cit7h","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1194\/jlr.M020438","volume":"53","author":"Lu S. C.","year":"2012","journal-title":"J. Lipid Res."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1126\/science.7973629","volume":"266","author":"Dawson P. E.","year":"1994","journal-title":"Science"},{"key":"ref9\/cit9a","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S1389-0352(01)00061-7","volume":"90","author":"Sadler K.","year":"2002","journal-title":"Rev. Mol. Biotechnol."},{"key":"ref9\/cit9b","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1071\/CH09065","volume":"62","author":"Zhong W.","year":"2009","journal-title":"Aust. J. Chem."},{"key":"ref9\/cit9c","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1021\/bc100130r","volume":"21","author":"Angeles-Boza A. M.","year":"2010","journal-title":"Bioconj. Chem."},{"key":"ref9\/cit9d","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.bmc.2010.07.058","volume":"19","author":"Breurken M.","year":"2011","journal-title":"Bioorg. Med. Chem."},{"key":"ref10\/cit10a","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1161\/01.ATV.16.2.328","volume":"16","author":"Palgunachari M. N.","year":"1996","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"ref10\/cit10b","doi-asserted-by":"crossref","first-page":"39477","DOI":"10.1074\/jbc.M207005200","volume":"277","author":"Panagotopulos S. E.","year":"2002","journal-title":"J. Biol. Chem."},{"key":"ref11\/cit11a","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1194\/jlr.M500531-JLR200","volume":"47","author":"Duong P. T.","year":"2006","journal-title":"J. Lipid Res."},{"key":"ref11\/cit11b","doi-asserted-by":"crossref","first-page":"14348","DOI":"10.1021\/ja074753y","volume":"129","author":"Chromy B. A.","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"ref12\/cit12a","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0021-9150(01)00713-4","volume":"163","author":"Rothblat G. H.","year":"2002","journal-title":"Atherosclerosis"},{"key":"ref12\/cit12b","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1161\/ATVBAHA.109.199158","volume":"30","author":"de la Llera-Moya M.","year":"2010","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"ref12\/cit12c","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1097\/MOL.0b013e328353eef1","volume":"23","author":"Kane J. P.","year":"2012","journal-title":"Curr. Opin. Lipidol."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"7524","DOI":"10.1021\/jp101889k","volume":"114","author":"Khelashvili G.","year":"2010","journal-title":"J. Phys. Chem. B"},{"key":"ref14\/cit14a","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1161\/01.ATV.21.1.13","volume":"21","author":"von Eckardstein A.","year":"2001","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"ref14\/cit14b","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1152\/physrev.00005.2005","volume":"85","author":"Oram J. F.","year":"2005","journal-title":"Physiol. Rev."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1194\/jlr.M700385-JLR200","volume":"49","author":"Troutt J. S.","year":"2008","journal-title":"J. Lipid Res."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1016\/S0022-2275(20)31538-8","volume":"42","author":"Li H.-H.","year":"2001","journal-title":"J. Lipid Res."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0022-2275(20)43208-0","volume":"31","author":"Ishida B. Y.","year":"1990","journal-title":"J. Lipid Res."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s00726-005-0289-3","volume":"30","author":"Werle M.","year":"2006","journal-title":"Amino Acids"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/FJC.0b013e31815ed0b9","volume":"51","author":"Graversen Jonas H.","year":"2008","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"ref20\/cit20a","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1161\/ATVBAHA.107.142570","volume":"27","author":"Zadelaar S.","year":"2007","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"ref20\/cit20b","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1080\/AC.67.1.2146561","volume":"67","author":"Van Craeyveld E.","year":"2012","journal-title":"Acta Cardiol."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"468","DOI":"10.2174\/138920308785915227","volume":"9","author":"Pini A.","year":"2008","journal-title":"Curr. Protein Pept. Sci."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/FJC.0b013e31815ed0b9","volume":"51","author":"Graversen J. H.","year":"2007","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"ref23\/cit23a","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1194\/jlr.M003665","volume":"51","author":"Bielicki J. K.","year":"2010","journal-title":"J. Lipid Res."},{"key":"ref23\/cit23b","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.atherosclerosis.2012.10.064","volume":"227","author":"Handattu S. P.","year":"2013","journal-title":"Atherosclerosis"},{"key":"ref23\/cit23c","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1194\/jlr.M013144","volume":"52","author":"Navab M.","year":"2011","journal-title":"J. Lipid Res."},{"key":"ref24\/cit24a","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1161\/01.CIR.99.1.105","volume":"99","author":"Benoit P.","year":"1999","journal-title":"Circulation"},{"key":"ref24\/cit24b","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1161\/hc2501.092494","volume":"103","author":"Shah P. K.","year":"2001","journal-title":"Circulation"},{"key":"ref24\/cit24c","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1038\/bjp.2008.122","volume":"154","author":"Busseuil D.","year":"2008","journal-title":"Br. J. Pharmacol."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0065-3233(08)60643-9","volume":"45","author":"Segrest J. P.","year":"1994","journal-title":"Adv. Protein Chem."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1194\/jlr.M011098","volume":"52","author":"Watson C. E.","year":"2011","journal-title":"J. Lipid Res."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1194\/jlr.P800003-JLR200","volume":"49","author":"Bloedon L. T.","year":"2008","journal-title":"J. Lipid Res."},{"key":"ref28\/cit28","unstructured":"http:\/\/www.prnewswire.co.uk\/news-releases\/esperion-reports-positive-results-for-second-phase-1-study-of-etc-642-155462665.html, accessed in February 2013."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1161\/hc0302.103711","volume":"105","author":"Navab M.","year":"2002","journal-title":"Circulation"},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1194\/jlr.M800539-JLR200","volume":"50","author":"Navab M.","year":"2009","journal-title":"J. Lipid Res."}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ja404714a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,2]],"date-time":"2023-04-02T23:29:55Z","timestamp":1680478195000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ja404714a"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,26]]},"references-count":62,"journal-issue":{"issue":"36","published-print":{"date-parts":[[2013,9,11]]}},"alternative-id":["10.1021\/ja404714a"],"URL":"https:\/\/doi.org\/10.1021\/ja404714a","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718087155.793485850","asserted-by":"object"}]},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,26]]}}}