{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:07:29Z","timestamp":1791846449389,"version":"4.3.4"},"reference-count":66,"publisher":"American Chemical Society (ACS)","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2009,6,3]]},"DOI":"10.1021\/ja809284s","type":"journal-article","created":{"date-parts":[[2009,5,21]],"date-time":"2009-05-21T14:39:00Z","timestamp":1242916740000},"page":"7327-7333","source":"Crossref","is-referenced-by-count":111,"title":["General Synthetic Route to Cell-Permeable Block Copolymers via ROMP"],"prefix":"10.1021","volume":"131","author":[{"given":"Erin M.","family":"Kolonko","sequence":"first","affiliation":[{"name":"Departments of Chemistry and Biochemistry, University of Wisconsin\u2212Madison, Madison, Wisconsin 53706"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason K.","family":"Pontrello","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Biochemistry, University of Wisconsin\u2212Madison, Madison, Wisconsin 53706"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane L.","family":"Mangold","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Biochemistry, University of Wisconsin\u2212Madison, Madison, Wisconsin 53706"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura L.","family":"Kiessling","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Biochemistry, University of Wisconsin\u2212Madison, Madison, Wisconsin 53706"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2009,5,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nrd1088","volume":"2","author":"Duncan R.","year":"2003","journal-title":"Nat. Rev. Drug Discov."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/macp.200290073","volume":"204","author":"Lodge T. P.","year":"2003","journal-title":"Macromol. Chem. Phys."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1002\/adma.200401291","volume":"17","author":"Shenhar R.","year":"2005","journal-title":"Adv. Mater."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/12_005","volume":"189","author":"Hadjichristidis N.","year":"2005","journal-title":"Adv. Polym. Sci."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1021\/ja01592a101","volume":"78","author":"Szwarc M.","year":"1956","journal-title":"J. Am. Chem. Soc."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"4649","DOI":"10.1021\/ma00044a028","volume":"25","author":"Iatrou H.","year":"1992","journal-title":"Macromolecules"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1016\/0032-3861(92)90890-9","volume":"33","author":"Fujimoto T","year":"1992","journal-title":"Polymer"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/masy.19940850117","volume":"85","author":"Yin R.","year":"1994","journal-title":"Macromol. Symp."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.1021\/ja963519x","volume":"119","author":"Choi S. K.","year":"1997","journal-title":"J. Am. Chem. Soc."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"6193","DOI":"10.1021\/ja990223t","volume":"121","author":"Strong L. E.","year":"1999","journal-title":"J. Am. Chem. Soc."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"14536","DOI":"10.1021\/ja053931p","volume":"127","author":"Pontrello J. K.","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"S416","DOI":"10.1088\/0957-4484\/16\/7\/016","volume":"16","author":"Carrillo A.","year":"2005","journal-title":"Nanotechnology"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1021\/bm060210p","volume":"7","author":"Gujraty K. V.","year":"2006","journal-title":"Biomacromolecules"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"4823","DOI":"10.1021\/ja058364k","volume":"128","author":"Ladmiral V.","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1021\/ma702052k","volume":"41","author":"Yang S. K.","year":"2008","journal-title":"Macromolecules"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.progpolymsci.2006.08.006","volume":"32","author":"Bielawski C. W.","year":"2007","journal-title":"Prog. Polym. Sci."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1021\/ma052560u","volume":"39","author":"Singh R.","year":"2006","journal-title":"Macromolecules"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1021\/ar000114f","volume":"34","author":"Trnka T. M.","year":"2001","journal-title":"Acc. Chem. Res."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"4592","DOI":"10.1002\/anie.200300576","volume":"42","author":"Schrock R. R.","year":"2003","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"2039","DOI":"10.1002\/anie.199520391","volume":"34","author":"Schwab P.","year":"1995","journal-title":"Angew. Chem., Int. Ed. Engl."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1021\/ma00185a012","volume":"21","author":"Cannizzo L. F.","year":"1988","journal-title":"Macromolecules"},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1021\/ma00005a043","volume":"24","author":"Mitchell J. P.","year":"1991","journal-title":"Macromolecules"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"7328","DOI":"10.1021\/ja00069a035","volume":"115","author":"Albagli D.","year":"1993","journal-title":"J. Am. Chem. Soc."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"8141","DOI":"10.1016\/S0040-4020(99)00304-X","volume":"55","author":"Schrock R. R.","year":"1999","journal-title":"Tetrahedron"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1021\/ma990872p","volume":"33","author":"Gibson V. C.","year":"2000","journal-title":"Macromolecules"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S1074-5521(00)00060-0","volume":"7","author":"Gordon E. J.","year":"2000","journal-title":"Chem. Biol."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"2293","DOI":"10.1021\/ol0259239","volume":"4","author":"Owen R. M.","year":"2002","journal-title":"Org. Lett."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"7117","DOI":"10.1016\/j.tet.2004.05.124","volume":"60","author":"Grubbs R. H.","year":"2004","journal-title":"Tetrahedron"},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/masy.200451319","volume":"217","author":"Riegler S.","year":"2004","journal-title":"Macromol. Symp."},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1002\/marc.200400150","volume":"25","author":"Slugovc C.","year":"2004","journal-title":"Macromol. Rapid Commun."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"8045","DOI":"10.1002\/anie.200602323","volume":"45","author":"Hilf S.","year":"2006","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1002\/marc.200700083","volume":"28","author":"Hilf S.","year":"2007","journal-title":"Macromol. Rapid Commun."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"11040","DOI":"10.1021\/ja8022863","volume":"130","author":"Hilf S.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"5626","DOI":"10.1021\/ma800980p","volume":"41","author":"Matson J. B.","year":"2008","journal-title":"Macromolecules"},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"2913","DOI":"10.1002\/pola.22622","volume":"46","author":"Hilf S.","year":"2008","journal-title":"J. Polym. Sci., Part A: Polym. Chem."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1021\/bc800449s","volume":"20","author":"Miki K.","year":"2009","journal-title":"Bioconjugate Chem."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"3253","DOI":"10.1021\/ol048935y","volume":"6","author":"Roberts K. S.","year":"2004","journal-title":"Org. Lett."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"4168","DOI":"10.1021\/ja056378k","volume":"128","author":"Bertin P. A.","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"9321","DOI":"10.1021\/ma0480087","volume":"37","author":"Binder W. H.","year":"2004","journal-title":"Macromolecules"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/pola.21867","volume":"45","author":"Kluger C.","year":"2007","journal-title":"J. Polym. Sci., Part A: Polym. Chem."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1021\/ol991208w","volume":"2","author":"Barrett A. G. M.","year":"2000","journal-title":"Org. Lett."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"6534","DOI":"10.1021\/ja061383p","volume":"128","author":"Allen M. J.","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1002\/pola.21219","volume":"44","author":"Carrillo A.","year":"2006","journal-title":"J. Poly. Sci. A: Polym. Chem."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1021\/cr0103423","volume":"102","author":"Barrett A. G. M.","year":"2002","journal-title":"Chem. Rev."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"16508","DOI":"10.1021\/jp047726s","volume":"108","author":"Xiao S. J.","year":"2004","journal-title":"J. Phys. Chem. B"},{"key":"ref46\/cit46","first-page":"3","volume":"38","author":"Harned A. M.","year":"2005","journal-title":"Aldrichim. Acta"},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"4613","DOI":"10.1016\/j.polymer.2006.04.049","volume":"47","author":"Liaw D. J.","year":"2006","journal-title":"Polymer"},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1042\/bj0740577","volume":"74","author":"Lindley H.","year":"1960","journal-title":"Biochem. J."},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1016\/j.chembiol.2004.08.023","volume":"11","author":"Barglow K. T.","year":"2004","journal-title":"Chem. Biol."},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"6019","DOI":"10.1016\/j.bmcl.2006.08.124","volume":"16","author":"Rajakumar P.","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"5626","DOI":"10.1021\/ja8001716","volume":"130","author":"Kolonko E. M.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1002\/anie.200600680","volume":"45","author":"Grubbs R. H.","year":"2006","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.1002\/1521-3773(20021104)41:21<4035::AID-ANIE4035>3.0.CO;2-I","volume":"41","author":"Love J. A.","year":"2002","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1002\/anie.200250632","volume":"42","author":"Choi T. L.","year":"2003","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"12053","DOI":"10.1021\/ja00105a056","volume":"116","author":"Mortell K. H.","year":"1994","journal-title":"J. Am. Chem. Soc."},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1021\/ja003305m","volume":"123","author":"Maynard H. D.","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1002\/anie.200502794","volume":"45","author":"Kiessling L. L.","year":"2006","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.sbi.2006.05.015","volume":"16","author":"Lee Y.","year":"2006","journal-title":"Curr. Opin. Struct. Biol."},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1080\/15583720701455186","volume":"47","author":"Smith D.","year":"2007","journal-title":"Polym. Rev."},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1021\/cb600489g","volume":"2","author":"Puffer E. B.","year":"2007","journal-title":"ACS Chem. Biol."},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.cbpa.2008.09.022","volume":"12","author":"Binder J. B.","year":"2008","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"2997","DOI":"10.1021\/ol800932w","volume":"10","author":"Mangold S. L.","year":"2008","journal-title":"Org. Lett."},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1073\/pnas.0807207106","volume":"106","author":"Courtney A. H.","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref64\/cit64","doi-asserted-by":"crossref","first-page":"5626\u2212+","DOI":"10.1021\/ja8001716","volume":"130","author":"Kolonko E. M.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref65\/cit65","doi-asserted-by":"crossref","first-page":"6672","DOI":"10.1002\/pola.22950","volume":"46","author":"Alfred S. F.","year":"2008","journal-title":"J. Polym. Sci., Part A: Polym. Chem."},{"key":"ref66\/cit66","doi-asserted-by":"crossref","first-page":"15372","DOI":"10.1021\/ja045063m","volume":"126","author":"Bontempo D.","year":"2004","journal-title":"J. Am. Chem. Soc."}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ja809284s","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T13:34:02Z","timestamp":1678973642000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ja809284s"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,7]]},"references-count":66,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2009,6,3]]}},"alternative-id":["10.1021\/ja809284s"],"URL":"https:\/\/doi.org\/10.1021\/ja809284s","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,7]]}}}