{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:41:29Z","timestamp":1777434089546,"version":"3.51.4"},"reference-count":33,"publisher":"American Chemical Society (ACS)","issue":"43","license":[{"start":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T00:00:00Z","timestamp":1595548800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T00:00:00Z","timestamp":1595548800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T00:00:00Z","timestamp":1595548800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["F30CA236131"],"award-info":[{"award-number":["F30CA236131"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000185","name":"Defense Advanced Research Projects Agency","doi-asserted-by":"publisher","award":["W911NF-14-2-0022"],"award-info":[{"award-number":["W911NF-14-2-0022"]}],"id":[{"id":"10.13039\/100000185","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001021","name":"Damon Runyon Cancer Research Foundation","doi-asserted-by":"publisher","award":["DRG-2250-16"],"award-info":[{"award-number":["DRG-2250-16"]}],"id":[{"id":"10.13039\/100001021","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["12GRNT11920011"],"award-info":[{"award-number":["12GRNT11920011"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["I140400"],"award-info":[{"award-number":["I140400"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["WI3285\/6-1"],"award-info":[{"award-number":["WI3285\/6-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1S10OD012359"],"award-info":[{"award-number":["1S10OD012359"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32 HL007751"],"award-info":[{"award-number":["T32 HL007751"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["2P41GM103391"],"award-info":[{"award-number":["2P41GM103391"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2020,10,28]]},"DOI":"10.1021\/jacs.0c04675","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T17:50:26Z","timestamp":1595613026000},"page":"18369-18377","source":"Crossref","is-referenced-by-count":10,"title":["Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome"],"prefix":"10.1021","volume":"142","author":[{"given":"Emilianne M.","family":"Limbrick","sequence":"first","affiliation":[{"name":"Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Graf","sequence":"additional","affiliation":[{"name":"Institute of Biochemistry and Molecular Biology, University of Hamburg, Hamburg 20146, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dagmara K.","family":"Derewacz","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Munich, 81377 Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9198-5498","authenticated-orcid":true,"given":"Jeffrey M.","family":"Spraggins","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States"},{"name":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37205, United States"},{"name":"Mass Spectrometry Research Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximiliane","family":"Wieland","sequence":"additional","affiliation":[{"name":"Institute of Biochemistry and Molecular Biology, University of Hamburg, Hamburg 20146, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Audrey E.","family":"Ynigez-Gutierrez","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin J.","family":"Reisman","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris","family":"Zinshteyn","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Genetics, Johns Hopkins University. Baltimore, Maryland 21205, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9077-3821","authenticated-orcid":true,"given":"Kathryn M.","family":"McCulloch","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. M.","family":"Iverson","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37205, United States"},{"name":"Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States"},{"name":"Vanderbilt Center for Structural Biology, Nashville, Tennessee 37232, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Genetics, Johns Hopkins University. Baltimore, Maryland 21205, United States"},{"name":"Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3816-3828","authenticated-orcid":true,"given":"Daniel N.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Institute of Biochemistry and Molecular Biology, University of Hamburg, Hamburg 20146, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5815-1176","authenticated-orcid":true,"given":"Brian O.","family":"Bachmann","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States"},{"name":"Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37205, United States"},{"name":"Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States"},{"name":"Vanderbilt Institute of Chemical Biology, Nashville, Tennessee 37205, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2020,7,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1659"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1934677100"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1998.2509"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2016.09.013"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1500964112"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4501"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1614297113"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0337542100"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2164(04)54004-2"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1039\/c39760000609"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)88126-6"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz310"},{"issue":"0","key":"ref13\/cit13","first-page":"203","volume":"33","author":"Shlaes D. M.","year":"1993","journal-title":"Program and Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1039\/c39800000056"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1604790113"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.071527498"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1614297113"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.35.866"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4057"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(88)64058-4"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.04.014"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.3034"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01673-13"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.1.1-12.2001"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.11.3339-3342.2002"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/bi101336u"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b04915"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2013.06.078"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201811131"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.3.577"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2003.03558.x"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02602.x"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1039\/C7NP00006E"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.0c04675","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T04:07:55Z","timestamp":1682568475000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.0c04675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,24]]},"references-count":33,"journal-issue":{"issue":"43","published-print":{"date-parts":[[2020,10,28]]}},"alternative-id":["10.1021\/jacs.0c04675"],"URL":"https:\/\/doi.org\/10.1021\/jacs.0c04675","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,24]]}}}