{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T12:50:45Z","timestamp":1792759845677,"version":"4.5.0"},"reference-count":65,"publisher":"American Chemical Society (ACS)","issue":"25","license":[{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture","doi-asserted-by":"publisher","award":["1025336"],"award-info":[{"award-number":["1025336"]}],"id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["201903250087"],"award-info":[{"award-number":["201903250087"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R35GM118056"],"award-info":[{"award-number":["R35GM118056"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2021,6,30]]},"DOI":"10.1021\/jacs.1c03988","type":"journal-article","created":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T13:16:32Z","timestamp":1623849392000},"page":"9575-9584","source":"Crossref","is-referenced-by-count":69,"title":["Harzianic Acid from <i>Trichoderma afroharzianum<\/i> Is a Natural Product Inhibitor of Acetohydroxyacid Synthase"],"prefix":"10.1021","volume":"143","author":[{"given":"Linan","family":"Xie","sequence":"first","affiliation":[{"name":"Biotechnology Research Institute, The Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Beijing 100081, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bio-organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5297-7046","authenticated-orcid":true,"given":"Wei","family":"Cheng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Texas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, Texas 77054, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5795-3804","authenticated-orcid":true,"given":"Jiahai","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bio-organic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Shanghai 200032, China"},{"name":"CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6135-8661","authenticated-orcid":true,"given":"Mengbin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1597-0141","authenticated-orcid":true,"given":"Yi","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,6,16]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1039\/b821578b"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1039\/C4NP00060A"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2009.01.046"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2015.04.001"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3390\/molecules19079760"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/ps.4458"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbi.2005.05.015"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3054.2001.1110211.x"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pp.36.060185.002505"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.2174\/1874437001408010127"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-765X.2009.02599.x"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.3852\/14-147"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1094\/PDIS.2000.84.4.377"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2016.01520"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1104\/pp.108.123810"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1094\/PHYTO-03-10-0091"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1007\/s10526-015-9662-7"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1094\/PHYTO.2004.94.2.147"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1007\/s10725-011-9610-1"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1515\/znc-2002-5-611"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2013.08.011"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-013-5344-5"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-765X.2006.01939.x"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1069"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1819998116"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/np900548p"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.47.731"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.57.235"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6968.12231"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.8b06503"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1039\/b413523g"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b00715"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1039\/D0OB02545C"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2001.5419"},{"issue":"1","key":"ref35\/cit35","first-page":"1","volume":"33","author":"Duggleby R. G.","year":"2000","journal-title":"J. Biochem. Mol. Biol."},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b01534"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/ol503717r"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0319-4"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1039\/C9NP00050J"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1039\/C8SC01325J"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.6b00213"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-005-0297-3"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1616142114"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2007.12.004"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1033.2003.03671.x"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0508701103"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1017\/S0890037X00022879"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)41484-0"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/bi983013m"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41429-019-0197-5"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/ja9056079"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.8b00173"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M211648200"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1002\/slct.201702128"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0171443"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1714392115"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1809422115"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0408210101"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1614\/0043-1745(2002)050[0700:RROWTA]2.0.CO;2"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01809-12"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.26928-0"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.034348-0"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1021\/jm301501k"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.0c00229"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1177\/1087057111433459"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.1c03988","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T13:36:19Z","timestamp":1681738579000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.1c03988"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,16]]},"references-count":65,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2021,6,30]]}},"alternative-id":["10.1021\/jacs.1c03988"],"URL":"https:\/\/doi.org\/10.1021\/jacs.1c03988","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,16]]}}}