{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T20:31:17Z","timestamp":1792269077818,"version":"4.4.0"},"reference-count":73,"publisher":"American Chemical Society (ACS)","issue":"48","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["2R01GM109054"],"award-info":[{"award-number":["2R01GM109054"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2021,12,8]]},"DOI":"10.1021\/jacs.1c09587","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T17:36:19Z","timestamp":1637602579000},"page":"20042-20048","source":"Crossref","is-referenced-by-count":91,"title":["Olefination via Cu-Mediated Dehydroacylation of Unstrained Ketones"],"prefix":"10.1021","volume":"143","author":[{"given":"Xukai","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1331-6015","authenticated-orcid":true,"given":"Guangbin","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"ref1\/cit1","unstructured":"March, J. March\u2019s advanced organic chemistry: reactions, mechanisms, and structure, eighth ed. Smith, M. B., Ed. John Wiley & Sons, Inc.: NJ, 2020; pp 891\u20131085."},{"key":"ref2\/cit2","unstructured":"Takeda, T. Modern Carbonyl Olefination: Methods and Applications; Wiley\u2013VCH: Weinheim, Germany, 2006; pp 1\u2013338."},{"key":"ref3\/cit3a","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1561357"},{"key":"ref3\/cit3b","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2018.04.057"},{"key":"ref3\/cit3c","unstructured":"cAnanikov, V. P.; Beletskaya, I. P.; Tanaka, M. Hydrofunctionalization; Springer Berlin Heidelberg: Berlin, Heidelberg, 2013; pp 1\u201319."},{"key":"ref4\/cit4a","doi-asserted-by":"publisher","DOI":"10.1021\/cr050051k"},{"key":"ref4\/cit4b","doi-asserted-by":"publisher","DOI":"10.1039\/B611547K"},{"key":"ref4\/cit4c","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC02399D"},{"key":"ref4\/cit4d","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.0c01174"},{"key":"ref4\/cit4e","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00447B"},{"key":"ref5\/cit5a","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.6b02333"},{"key":"ref5\/cit5b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201905218"},{"key":"ref6\/cit6a","doi-asserted-by":"publisher","DOI":"10.1126\/science.1261232"},{"key":"ref6\/cit6b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201503620"},{"key":"ref6\/cit6c","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b06069"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1126\/science.aae0427"},{"key":"ref8\/cit8a","doi-asserted-by":"publisher","DOI":"10.1016\/0040-4020(68)88124-4"},{"key":"ref8\/cit8b","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b01965"},{"key":"ref8\/cit8c","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.8b03282"},{"key":"ref8\/cit8d","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-018-0142-4"},{"key":"ref8\/cit8e","doi-asserted-by":"publisher","DOI":"10.1039\/C8QO00585K"},{"key":"ref8\/cit8f","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.9b00167"},{"key":"ref9\/cit9a","doi-asserted-by":"publisher","DOI":"10.1039\/c2cc18093f"},{"key":"ref9\/cit9b","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14993"},{"key":"ref9\/cit9c","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2798"},{"key":"ref9\/cit9d","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.7b04281"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/ja983197s"},{"key":"ref11\/cit11a","doi-asserted-by":"publisher","DOI":"10.1039\/C4QO00053F"},{"key":"ref11\/cit11b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.6b00554"},{"key":"ref11\/cit11c","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00253C"},{"key":"ref11\/cit11d","doi-asserted-by":"publisher","DOI":"10.1016\/j.trechm.2019.12.002"},{"key":"ref11\/cit11e","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-020-0218-8"},{"key":"ref12\/cit12a","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2014.09.005"},{"key":"ref12\/cit12b","doi-asserted-by":"publisher","DOI":"10.1039\/C4QO00154K"},{"key":"ref12\/cit12c","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.0c01519"},{"key":"ref13\/cit13a","doi-asserted-by":"publisher","DOI":"10.1039\/C3OB42050G"},{"key":"ref13\/cit13b","doi-asserted-by":"publisher","DOI":"10.1039\/C5CS00272A"},{"key":"ref14\/cit14a","doi-asserted-by":"publisher","DOI":"10.1021\/cr020022z"},{"key":"ref14\/cit14b","doi-asserted-by":"publisher","DOI":"10.1021\/cr0683515"},{"key":"ref14\/cit14c","doi-asserted-by":"publisher","DOI":"10.1021\/cr068424k"},{"key":"ref14\/cit14d","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2017.03.044"},{"key":"ref14\/cit14e","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00692"},{"key":"ref14\/cit14f","doi-asserted-by":"publisher","DOI":"10.1021\/cr020044l"},{"key":"ref14\/cit14g","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2005.07.077"},{"key":"ref15\/cit15a","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2016.07.081"},{"key":"ref15\/cit15b","doi-asserted-by":"publisher","DOI":"10.1039\/D0CY01820A"},{"key":"ref16\/cit16a","doi-asserted-by":"publisher","DOI":"10.1021\/cr400628s"},{"key":"ref16\/cit16b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c00335"},{"key":"ref16\/cit16c","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201305010"},{"key":"ref16\/cit16d","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5b03367"},{"key":"ref17\/cit17a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201303696"},{"key":"ref17\/cit17b","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201500473"},{"key":"ref17\/cit17c","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC05336K"},{"key":"ref17\/cit17d","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b01717"},{"key":"ref17\/cit17e","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-0926-8"},{"key":"ref17\/cit17f","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c01724"},{"key":"ref17\/cit17g","doi-asserted-by":"publisher","DOI":"10.1038\/s41929-021-00661-7"},{"key":"ref17\/cit17h","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c05092"},{"key":"ref17\/cit17i","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2021.03.023"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201914623"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/1099-0682(200102)2001:2<529::AID-EJIC529>3.0.CO;2-V"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/0040-4020(95)00730-V"},{"key":"ref21\/cit21a","doi-asserted-by":"publisher","DOI":"10.1021\/ja01017a022"},{"key":"ref21\/cit21b","doi-asserted-by":"publisher","DOI":"10.1021\/ja01019a018"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/ja306123m"},{"key":"ref23\/cit23","unstructured":"Phenyl\nalkyl ketone 1c\u2032 can be transformed to alkene 5c via\na two-step protocol. For other ketones, see the Supporting Information."},{"key":"ref24\/cit24","unstructured":"Ethyl 2,3-dimethyl-4-oxopentanoate\ncan be transformed to trisubstituted alkene 5as under\nthe standard conditions. For details, see the Supporting Information."},{"key":"ref25\/cit25a","doi-asserted-by":"publisher","DOI":"10.1021\/ja4117632"},{"key":"ref25\/cit25b","doi-asserted-by":"publisher","DOI":"10.1039\/C9OB00136K"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1088213"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/jo400428m"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/nature13231"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2013.07.057"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.1c09587","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T14:10:16Z","timestamp":1682518216000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.1c09587"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,22]]},"references-count":73,"journal-issue":{"issue":"48","published-print":{"date-parts":[[2021,12,8]]}},"alternative-id":["10.1021\/jacs.1c09587"],"URL":"https:\/\/doi.org\/10.1021\/jacs.1c09587","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,22]]}}}