{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:46:26Z","timestamp":1792784786994,"version":"4.5.0"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"22","license":[{"start":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T00:00:00Z","timestamp":1684454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T00:00:00Z","timestamp":1684454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T00:00:00Z","timestamp":1684454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"name":"Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education of Zhejiang Province, Hangzhou Normal University","award":["KFJJ2022010"],"award-info":[{"award-number":["KFJJ2022010"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2023,6,7]]},"DOI":"10.1021\/jacs.3c02179","type":"journal-article","created":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T23:45:01Z","timestamp":1684539901000},"page":"12193-12205","source":"Crossref","is-referenced-by-count":187,"title":["Oral Hydrogel Microbeads-Mediated In Situ Synthesis of Selenoproteins for Regulating Intestinal Immunity and Microbiota"],"prefix":"10.1021","volume":"145","author":[{"given":"Jiang","family":"Ouyang","sequence":"first","affiliation":[{"name":"Department of Oncology of the First Affiliated Hospital, Department of Chemistry, Jinan University, Guangzhou 510632, China"},{"name":"School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, Guangdong 511436, China"},{"name":"Center for Nanomedicine and Department of Anesthesiology, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Oncology of the First Affiliated Hospital, Department of Chemistry, Jinan University, Guangzhou 510632, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binhua","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Oncology of the First Affiliated Hospital, Department of Chemistry, Jinan University, Guangzhou 510632, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjiang","family":"Li","sequence":"additional","affiliation":[{"name":"Center for Nanomedicine and Department of Anesthesiology, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingyue","family":"Bu","sequence":"additional","affiliation":[{"name":"Department of Oncology of the First Affiliated Hospital, Department of Chemistry, Jinan University, Guangzhou 510632, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Oncology of the First Affiliated Hospital, Department of Chemistry, Jinan University, Guangzhou 510632, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingkai","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Oncology of the First Affiliated Hospital, Department of Chemistry, Jinan University, Guangzhou 510632, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2909-3023","authenticated-orcid":true,"given":"Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Center for Nanomedicine and Department of Anesthesiology, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Kong","sequence":"additional","affiliation":[{"name":"Center for Nanomedicine and Department of Anesthesiology, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianfeng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Oncology of the First Affiliated Hospital, Department of Chemistry, Jinan University, Guangzhou 510632, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4277-3728","authenticated-orcid":true,"given":"Wei","family":"Tao","sequence":"additional","affiliation":[{"name":"Center for Nanomedicine and Department of Anesthesiology, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,5,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay0939"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2021.08.011"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.mattod.2023.01.002"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c08434"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3390\/cells8050450"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2006.08.005"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.10.007"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.engreg.2021.09.003"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/SMMD.20220006"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.100975"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1039\/c3cs60272a"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00039.2013"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-022-01490-x"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2021.101351"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2022.738876"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2011.4145"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05174-2"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M000690200"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/bi00315a021"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2021.133095"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202101619"},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/B978-0-12-817055-7.00003-0","volume-title":"Natural Polysaccharides in Drug Delivery and Biomedical Applications","author":"Chaturvedi K.","year":"2019"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202008879"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2022.02.008"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28744-4"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-019-0462-9"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.04.015"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-019-0213-6"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-020-0331-7"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.8b00563"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.648162"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad9948"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1039\/D1FO03003E"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2022.04.028"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8111715"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2022.08.032"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.3c02179","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.3c02179","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T04:48:05Z","timestamp":1686113285000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.3c02179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,19]]},"references-count":36,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2023,6,7]]}},"alternative-id":["10.1021\/jacs.3c02179"],"URL":"https:\/\/doi.org\/10.1021\/jacs.3c02179","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,19]]}}}