{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T06:30:46Z","timestamp":1792477846848,"version":"4.5.0"},"reference-count":68,"publisher":"American Chemical Society (ACS)","issue":"36","license":[{"start":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T00:00:00Z","timestamp":1693180800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003006","name":"Eidgen?ssische Technische Hochschule Z?rich","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003006","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["SNSF 213812"],"award-info":[{"award-number":["SNSF 213812"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000848","name":"University of Edinburgh","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000848","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000854","name":"Human Frontier Science Program","doi-asserted-by":"publisher","award":["LT000861\/ 2020-L"],"award-info":[{"award-number":["LT000861\/ 2020-L"]}],"id":[{"id":"10.13039\/501100000854","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["757608"],"award-info":[{"award-number":["757608"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2023,9,13]]},"DOI":"10.1021\/jacs.3c05680","type":"journal-article","created":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T19:47:33Z","timestamp":1693252053000},"page":"19496-19502","source":"Crossref","is-referenced-by-count":40,"title":["Late-Stage Molecular Editing Enabled by Ketone Chain-Walking Isomerization"],"prefix":"10.1021","volume":"145","author":[{"given":"Yannick","family":"Br\u00e4gger","sequence":"first","affiliation":[{"name":"ETH Z\u00fcrich, Vladimir-Prelog-Weg 3, HCI, 8093 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ori","family":"Green","sequence":"additional","affiliation":[{"name":"ETH Z\u00fcrich, Vladimir-Prelog-Weg 3, HCI, 8093 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8552-1547","authenticated-orcid":true,"given":"Benjamin N.","family":"Bhawal","sequence":"additional","affiliation":[{"name":"ETH Z\u00fcrich, Vladimir-Prelog-Weg 3, HCI, 8093 Z\u00fcrich, Switzerland"},{"name":"School of Chemistry, University of Edinburgh, Edinburgh EH9 3FJ, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3968-1424","authenticated-orcid":true,"given":"Bill","family":"Morandi","sequence":"additional","affiliation":[{"name":"ETH Z\u00fcrich, Vladimir-Prelog-Weg 3, HCI, 8093 Z\u00fcrich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,8,28]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200904761"},{"key":"ref2\/cit2a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201201787"},{"key":"ref2\/cit2b","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.9b00916"},{"key":"ref2\/cit2c","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-021-00300-6"},{"key":"ref2\/cit2d","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c10783"},{"key":"ref3\/cit3a","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b07136"},{"key":"ref3\/cit3b","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2835"},{"key":"ref3\/cit3c","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0755-1"},{"key":"ref3\/cit3d","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c11552"},{"key":"ref3\/cit3e","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c11681"},{"key":"ref3\/cit3f","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c12043"},{"key":"ref3\/cit3g","doi-asserted-by":"publisher","DOI":"10.1126\/science.add6852"},{"key":"ref3\/cit3h","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c04743"},{"key":"ref4\/cit4a","doi-asserted-by":"publisher","DOI":"10.1021\/cr0104375"},{"key":"ref4\/cit4b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201906124"},{"key":"ref4\/cit4c","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00324"},{"key":"ref4\/cit4d","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.1c00190"},{"key":"ref5\/cit5a","doi-asserted-by":"publisher","DOI":"10.1126\/science.1962206"},{"key":"ref5\/cit5b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199502591"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1039\/b821200g"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-1937-1"},{"key":"ref8\/cit8a","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2445"},{"key":"ref8\/cit8b","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.8b00005"},{"key":"ref8\/cit8c","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC02399D"},{"key":"ref9\/cit9a","doi-asserted-by":"publisher","DOI":"10.1021\/ja00062a066"},{"key":"ref9\/cit9b","doi-asserted-by":"publisher","DOI":"10.1021\/ar700133y"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1126\/science.abl7854"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.26434\/chemrxiv-2023-rchb2"},{"key":"ref12\/cit12a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201803797"},{"key":"ref12\/cit12b","doi-asserted-by":"publisher","DOI":"10.1002\/ijch.201700116"},{"key":"ref12\/cit12c","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.6b02333"},{"key":"ref13\/cit13a","doi-asserted-by":"publisher","DOI":"10.1126\/science.aae0427"},{"key":"ref13\/cit13b","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2798"},{"key":"ref13\/cit13c","doi-asserted-by":"publisher","DOI":"10.1126\/science.aam9041"},{"key":"ref13\/cit13d","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-018-0078-8"},{"key":"ref13\/cit13e","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201910436"},{"key":"ref13\/cit13f","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c03184"},{"key":"ref13\/cit13g","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf2974"},{"key":"ref13\/cit13h","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c00529"},{"key":"ref13\/cit13i","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2021.02.029"},{"key":"ref13\/cit13j","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.1c00442"},{"key":"ref13\/cit13k","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c01595"},{"key":"ref14\/cit14a","doi-asserted-by":"publisher","DOI":"10.1126\/science.add1383"},{"key":"ref14\/cit14b","doi-asserted-by":"publisher","DOI":"10.1039\/D2SC06952K"},{"key":"ref15\/cit15a","doi-asserted-by":"publisher","DOI":"10.1002\/cber.18870200278"},{"key":"ref15\/cit15b","doi-asserted-by":"publisher","DOI":"10.1002\/jlac.19234310111"},{"key":"ref15\/cit15c","doi-asserted-by":"publisher","DOI":"10.1039\/c3cs60154d"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201601329"},{"key":"ref17\/cit17a","doi-asserted-by":"publisher","DOI":"10.1135\/cccc19860118"},{"key":"ref17\/cit17b","doi-asserted-by":"publisher","DOI":"10.1002\/jhet.5570260517"},{"key":"ref18\/cit18a","doi-asserted-by":"publisher","DOI":"10.1021\/cr0684016"},{"key":"ref18\/cit18b","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-02815-1_21"},{"key":"ref18\/cit18c","doi-asserted-by":"publisher","DOI":"10.1039\/b701216k"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1290107"},{"key":"ref20\/cit20a","doi-asserted-by":"publisher","DOI":"10.1021\/ja952692a"},{"key":"ref20\/cit20b","doi-asserted-by":"publisher","DOI":"10.1021\/ja962163m"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1039\/C6OB01726F"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/jo00081a016"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/jm300262w"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/P19720000492"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2005.08.006"},{"key":"ref26\/cit26a","doi-asserted-by":"publisher","DOI":"10.1002\/9780470638859.conrr672"},{"key":"ref26\/cit26b","doi-asserted-by":"publisher","DOI":"10.1021\/ja01571a085"},{"key":"ref26\/cit26c","doi-asserted-by":"publisher","DOI":"10.1002\/jhet.5570260518"},{"key":"ref26\/cit26d","doi-asserted-by":"publisher","DOI":"10.1021\/ja01597a075"},{"key":"ref27\/cit27a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.196702941"},{"key":"ref27\/cit27b","doi-asserted-by":"publisher","DOI":"10.1021\/jo062141a"},{"key":"ref27\/cit27c","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2010.01.069"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.3c05680","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.3c05680","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T05:23:27Z","timestamp":1694582607000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.3c05680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,28]]},"references-count":68,"journal-issue":{"issue":"36","published-print":{"date-parts":[[2023,9,13]]}},"alternative-id":["10.1021\/jacs.3c05680"],"URL":"https:\/\/doi.org\/10.1021\/jacs.3c05680","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,28]]}}}