{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T22:43:11Z","timestamp":1780440191225,"version":"3.54.1"},"reference-count":43,"publisher":"American Chemical Society (ACS)","license":[{"start":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T00:00:00Z","timestamp":1727827200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["RGPIN-2019-04806"],"award-info":[{"award-number":["RGPIN-2019-04806"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CHE-2214606"],"award-info":[{"award-number":["CHE-2214606"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"DOI":"10.1021\/jacs.4c03905","type":"journal-article","created":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T13:25:57Z","timestamp":1727875557000},"source":"Crossref","is-referenced-by-count":3,"title":["Extended Sulfo-Pillar[6]arenes \u2500 a New Host Family and Its Application in the Binding of Direct Oral Anticoagulants"],"prefix":"10.1021","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6743-715X","authenticated-orcid":true,"given":"Chelsea R.","family":"Wilson","sequence":"first","affiliation":[{"name":"Department of Chemistry, University of Victoria, 3800 Finnerty Rd., Victoria, British Columbia V8P 5C2, Canada"},{"name":"Centre for Advanced Materials and Related Technology (CAMTEC), University of Victoria, 3800 Finnerty Rd., Victoria, British Columbia V8W 2Y2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Austia O.","family":"Puckett","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Victoria, 3800 Finnerty Rd., Victoria, British Columbia V8P 5C2, Canada"},{"name":"Centre for Advanced Materials and Related Technology (CAMTEC), University of Victoria, 3800 Finnerty Rd., Victoria, British Columbia V8W 2Y2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8832-4639","authenticated-orcid":true,"given":"Isabella M.","family":"Murray","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Victoria, 3800 Finnerty Rd., Victoria, British Columbia V8P 5C2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0511-1127","authenticated-orcid":true,"given":"Allen G.","family":"Oliver","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, Indiana 46556, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4658-9132","authenticated-orcid":true,"given":"Fraser","family":"Hof","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Victoria, 3800 Finnerty Rd., Victoria, British Columbia V8P 5C2, Canada"},{"name":"Centre for Advanced Materials and Related Technology (CAMTEC), University of Victoria, 3800 Finnerty Rd., Victoria, British Columbia V8W 2Y2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,10,2]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2015.1037274"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.7150\/thno.53459"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00454E"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.2147\/dddt.s2757"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/1521-3773(20020118)41:2<265::aid-anie265>3.0.co;2-q"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012763"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1039\/C9CS00622B"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.7150\/thno.31653"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00391A"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/cr500392w"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000868"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/jacsau.3c00273"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1039\/C2CS35233H"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201606881"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202004380"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-020-5058-1"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/rth2.12089"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.120.017559"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2018.04.004"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25475"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.4212\/cjhp.v69i5.1601"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2023.05.003"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202005902"},{"key":"ref24\/cit24","unstructured":"Isaacs, L. D., Xue, W. Sulfated pillararenes, methods of making same, and uses thereof. U.S. Patent 17\/822, 863, 2023. https:\/\/patents.google.com\/patent\/US20230174468A1\/en."},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2022.11.019"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1039\/D4CC00772G"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1039\/D2OB01487D"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2023.133607"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.15227\/orgsyn.099.0125"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1039\/c2sc20982a"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/jo302283n"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/s42004-020-00363-4"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28207009"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b01123"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2022.08.014"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1039\/D3CC05094G"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c07106"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2021.08.044"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/open.202300109"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2017.12.009"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2021.105415"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1039\/C5QO00159E"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2017.12.056"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.4c03905","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.4c03905","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T07:21:20Z","timestamp":1729063280000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.4c03905"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,2]]},"references-count":43,"alternative-id":["10.1021\/jacs.4c03905"],"URL":"https:\/\/doi.org\/10.1021\/jacs.4c03905","relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv-2024-q70p1","asserted-by":"object"}]},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,2]]},"article-number":"jacs.4c03905"}}