{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T00:00:12Z","timestamp":1787702412180,"version":"build-2784847793"},"reference-count":78,"publisher":"American Chemical Society (ACS)","issue":"38","license":[{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T00:00:00Z","timestamp":1726099200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22101172"],"award-info":[{"award-number":["22101172"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22371183"],"award-info":[{"award-number":["22371183"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2024,9,25]]},"DOI":"10.1021\/jacs.4c09276","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T16:16:31Z","timestamp":1726157791000},"page":"26387-26396","source":"Crossref","is-referenced-by-count":12,"title":["Enamine Acylation Enabled Desymmetrization of Malonic Esters"],"prefix":"10.1021","volume":"146","author":[{"given":"Yu-Ping","family":"He","sequence":"first","affiliation":[{"name":"Shanghai Frontiers Science Center for Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, and Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China"},{"name":"Department of Chemistry, College of Sciences, Shanghai University, Shanghai 200444, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuo-Chen","family":"Li","sequence":"additional","affiliation":[{"name":"Shanghai Frontiers Science Center for Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, and Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Qi","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Frontiers Science Center for Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, and Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Ya","family":"Zheng","sequence":"additional","affiliation":[{"name":"Shanghai Frontiers Science Center for Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, and Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0401-2434","authenticated-orcid":true,"given":"Hua","family":"Wu","sequence":"additional","affiliation":[{"name":"Shanghai Frontiers Science Center for Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy, and Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, Shanghai 200240, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,9,12]]},"reference":[{"key":"ref1\/cit1a","doi-asserted-by":"publisher","DOI":"10.1021\/ja01636a103"},{"key":"ref1\/cit1b","doi-asserted-by":"publisher","DOI":"10.1021\/ja00885a021"},{"key":"ref1\/cit1c","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)96050-7"},{"key":"ref2\/cit2a","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-18074"},{"key":"ref2\/cit2b","doi-asserted-by":"publisher","DOI":"10.1021\/ar0300571"},{"key":"ref3\/cit3a","doi-asserted-by":"publisher","DOI":"10.1021\/jo00925a003"},{"key":"ref3\/cit3b","doi-asserted-by":"publisher","DOI":"10.1021\/ja994280y"},{"key":"ref3\/cit3c","doi-asserted-by":"publisher","DOI":"10.1002\/anie.197104961"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.5b00028"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1126\/science.270.5243.1797"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/ja028812d"},{"key":"ref7\/cit7a","doi-asserted-by":"publisher","DOI":"10.1021\/ar3000822"},{"key":"ref7\/cit7b","doi-asserted-by":"publisher","DOI":"10.1021\/cr0684016"},{"key":"ref7\/cit7c","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201405038"},{"key":"ref7\/cit7d","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201503920"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-021-00715-0"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-023-01362-3"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32560-1"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/jo402853v"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.3987\/COM-18-S(F)87"},{"key":"ref13\/cit13a","doi-asserted-by":"publisher","DOI":"10.1002\/cber.188702001149"},{"key":"ref13\/cit13b","doi-asserted-by":"publisher","DOI":"10.1002\/cber.189402701202"},{"key":"ref13\/cit13c","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201607731"},{"key":"ref13\/cit13d","doi-asserted-by":"publisher","DOI":"10.1039\/D1CC05205E"},{"key":"ref13\/cit13e","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.2c01421"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201805578"},{"key":"ref15\/cit15a","doi-asserted-by":"publisher","DOI":"10.1021\/cr020061a"},{"key":"ref15\/cit15b","doi-asserted-by":"publisher","DOI":"10.1021\/cr0683764"},{"key":"ref15\/cit15c","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201309952"},{"key":"ref15\/cit15d","doi-asserted-by":"publisher","DOI":"10.1039\/C4CS00042K"},{"key":"ref16\/cit16a","doi-asserted-by":"crossref","DOI":"10.1201\/9781420067934","volume-title":"Advances in Friedel-Crafts Acylation Reactions: Catalytic and Green Processes","author":"Sartori G.","year":"2009","edition":"1"},{"key":"ref16\/cit16b","doi-asserted-by":"publisher","DOI":"10.1021\/jo900696k"},{"key":"ref17\/cit17a","doi-asserted-by":"publisher","DOI":"10.1021\/ja015717g"},{"key":"ref17\/cit17b","doi-asserted-by":"publisher","DOI":"10.1021\/ja0767480"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1055\/s-1999-2775"},{"key":"ref19\/cit19a","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2022.132629"},{"key":"ref19\/cit19b","doi-asserted-by":"publisher","DOI":"10.1038\/nature14007"},{"key":"ref19\/cit19c","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-926302"},{"key":"ref19\/cit19d","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3773(19980302)37:4<388::AID-ANIE388>3.0.CO;2-V"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.6b00094"},{"key":"ref21\/cit21a","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2015.09.134"},{"key":"ref21\/cit21b","doi-asserted-by":"publisher","DOI":"10.1021\/cr040640a"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200353240"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/ja0491533"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202317182"},{"key":"ref25\/cit25a","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201700361"},{"key":"ref25\/cit25b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201504697"},{"key":"ref25\/cit25c","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202402532"},{"key":"ref25\/cit25d","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC07780J"},{"key":"ref25\/cit25e","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-50400-2"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1039\/c1cc11253h"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1039\/c3mb70022d"},{"key":"ref28\/cit28a","doi-asserted-by":"publisher","DOI":"10.1021\/ja046259p"},{"key":"ref28\/cit28b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200502277"},{"key":"ref28\/cit28c","doi-asserted-by":"publisher","DOI":"10.1021\/ja076179w"},{"key":"ref28\/cit28d","doi-asserted-by":"publisher","DOI":"10.1021\/ja801514m"},{"key":"ref28\/cit28e","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200902420"},{"key":"ref28\/cit28f","doi-asserted-by":"publisher","DOI":"10.1126\/science.1182826"},{"key":"ref28\/cit28g","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b06811"},{"key":"ref28\/cit28h","doi-asserted-by":"publisher","DOI":"10.1126\/science.aao5894"},{"key":"ref28\/cit28i","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c06664"},{"key":"ref28\/cit28j","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202213831"},{"key":"ref28\/cit28k","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201912677"},{"key":"ref28\/cit28l","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202313797"},{"key":"ref28\/cit28m","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202217954"},{"key":"ref29\/cit29a","doi-asserted-by":"publisher","DOI":"10.1021\/cr068374j"},{"key":"ref29\/cit29b","doi-asserted-by":"publisher","DOI":"10.1039\/b817310a"},{"key":"ref29\/cit29c","doi-asserted-by":"publisher","DOI":"10.1021\/cr5001496"},{"key":"ref29\/cit29d","doi-asserted-by":"publisher","DOI":"10.1039\/C8OB00900G"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2013.01.090"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200705241"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201008071"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202000039"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201910917"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.22885"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpca.3c04374"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202113204"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.26812"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.4c09276","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.4c09276","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T15:40:04Z","timestamp":1727278804000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.4c09276"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,12]]},"references-count":78,"journal-issue":{"issue":"38","published-print":{"date-parts":[[2024,9,25]]}},"alternative-id":["10.1021\/jacs.4c09276"],"URL":"https:\/\/doi.org\/10.1021\/jacs.4c09276","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,12]]}}}