{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T04:21:09Z","timestamp":1793334069495,"version":"4.5.0"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002920","name":"Research Grants Council, University Grants Committee","doi-asserted-by":"publisher","award":["C7075-21GF"],"award-info":[{"award-number":["C7075-21GF"]}],"id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2022YFA1205700"],"award-info":[{"award-number":["2022YFA1205700"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22025105"],"award-info":[{"award-number":["22025105"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2235000"],"award-info":[{"award-number":["2235000"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82302266"],"award-info":[{"award-number":["82302266"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"publisher","award":["20230484237"],"award-info":[{"award-number":["20230484237"]}],"id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005090","name":"Beijing Nova Program","doi-asserted-by":"publisher","award":["20240484673"],"award-info":[{"award-number":["20240484673"]}],"id":[{"id":"10.13039\/501100005090","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005953","name":"Society of Hong Kong Scholars","doi-asserted-by":"publisher","award":["XJ2024052"],"award-info":[{"award-number":["XJ2024052"]}],"id":[{"id":"10.13039\/501100005953","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Harbin Medical University Cancer Hospital Haiyan Foundation","award":["JJYQ2024-03"],"award-info":[{"award-number":["JJYQ2024-03"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2025,2,5]]},"DOI":"10.1021\/jacs.4c15820","type":"journal-article","created":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T05:40:15Z","timestamp":1737697215000},"page":"4482-4492","source":"Crossref","is-referenced-by-count":23,"title":["Synergistic Enhancement of Ferroptosis via Mitochondrial Accumulation and Photodynamic-Controlled Release of an Organogold(I) Cluster Prodrug"],"prefix":"10.1021","volume":"147","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2005-2430","authenticated-orcid":true,"given":"Kui","family":"Xiao","sequence":"first","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, P. R. China"]},{"name":"Tsinghua University","place":["Beijing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7567-8663","authenticated-orcid":true,"given":"Da-Yong","family":"Hou","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience","place":["Beijing, P. R. China"]},{"name":"National Center for Nanoscience and Technology (NCNST)","place":["Beijing, P. R. China"]},{"name":"NHC and CAMS Key Laboratory of Molecular Probe and Targeted Theranostics, Heilongjiang Key Laboratory of Scientific Research in Urology","place":["Harbin, P. R. China"]},{"name":"Harbin Medical University","place":["Harbin, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ni-Yuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience","place":["Beijing, P. R. China"]},{"name":"National Center for Nanoscience and Technology (NCNST)","place":["Beijing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, P. R. China"]},{"name":"Tsinghua University","place":["Beijing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Yi","family":"Leung","sequence":"additional","affiliation":[{"name":"Institute of Molecular Functional Materials and Department of Chemistry","place":["Hong Kong, P. R. China"]},{"name":"The University of Hong Kong, Hong Kong Quantum AI Lab Limited","place":["Hong Kong, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wing-Kei","family":"Kwok","sequence":"additional","affiliation":[{"name":"Institute of Molecular Functional Materials and Department of Chemistry","place":["Hong Kong, P. R. China"]},{"name":"The University of Hong Kong, Hong Kong Quantum AI Lab Limited","place":["Hong Kong, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7407-0840","authenticated-orcid":true,"given":"Ziyong","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Molecular Functional Materials and Department of Chemistry","place":["Hong Kong, P. R. China"]},{"name":"The University of Hong Kong, Hong Kong Quantum AI Lab Limited","place":["Hong Kong, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cong","family":"Jin","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, P. R. China"]},{"name":"Tsinghua University","place":["Beijing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3442-7988","authenticated-orcid":true,"given":"Wanhai","family":"Xu","sequence":"additional","affiliation":[{"name":"NHC and CAMS Key Laboratory of Molecular Probe and Targeted Theranostics, Heilongjiang Key Laboratory of Scientific Research in Urology","place":["Harbin, P. R. China"]},{"name":"Harbin Medical University","place":["Harbin, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1961-0787","authenticated-orcid":true,"given":"Hao","family":"Wang","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience","place":["Beijing, P. R. China"]},{"name":"National Center for Nanoscience and Technology (NCNST)","place":["Beijing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8349-4429","authenticated-orcid":true,"given":"Vivian Wing-Wah","family":"Yam","sequence":"additional","affiliation":[{"name":"Institute of Molecular Functional Materials and Department of Chemistry","place":["Hong Kong, P. R. China"]},{"name":"The University of Hong Kong, Hong Kong Quantum AI Lab Limited","place":["Hong Kong, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4646-2887","authenticated-orcid":true,"given":"Liang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry","place":["Beijing, P. R. China"]},{"name":"Tsinghua University","place":["Beijing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,1,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202205900"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00209"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/D2CS00757F"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202218000"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.2c00649"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1039\/D1CS00933H"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2019.213175"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1515\/9783110470734-007"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32474-y"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c14275"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00074"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c07971"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c10381"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1039\/c1cc13767k"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2019.06.012"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c04677"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c11891"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c00096"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.organomet.2c00467"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.3c00302"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3109\/1354750X.2012.715672"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00271D"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202205429"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2013.07.036"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.202105043"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03820-9"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/nature24297"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30512-8"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.4657"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-1443"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2015.05.050"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.06.036"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-18-0212"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/ic00343a016"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889808042726"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/cg020063o"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1063\/1.472933"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1063\/1.478522"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/jp9716997"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.10189"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.7b01425"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/jp010187w"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b12124"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpca.8b08886"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.52.997"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.8b00841"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1063\/1.472460"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/ct800047t"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/ct6001187"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.22885"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/wcms.81"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1063\/5.0004608"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.4c15820","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.4c15820","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T04:15:37Z","timestamp":1738728937000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.4c15820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,24]]},"references-count":52,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,2,5]]}},"alternative-id":["10.1021\/jacs.4c15820"],"URL":"https:\/\/doi.org\/10.1021\/jacs.4c15820","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,24]]}}}