{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T21:10:41Z","timestamp":1787001041889,"version":"build-2736575974"},"reference-count":69,"publisher":"American Chemical Society (ACS)","issue":"22","license":[{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA278672"],"award-info":[{"award-number":["R01CA278672"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS096317"],"award-info":[{"award-number":["R01NS096317"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006151","name":"Basic Energy Sciences","doi-asserted-by":"publisher","award":["DE-AC02-05CH11231"],"award-info":[{"award-number":["DE-AC02-05CH11231"]}],"id":[{"id":"10.13039\/100006151","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R01GM126218"],"award-info":[{"award-number":["R01GM126218"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009975","name":"California State University, East Bay","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009975","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006235","name":"Lawrence Berkeley National Laboratory","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006235","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2025,6,4]]},"DOI":"10.1021\/jacs.5c01512","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T09:51:12Z","timestamp":1747993872000},"page":"18685-18693","source":"Crossref","is-referenced-by-count":14,"title":["A Solvatochromic Near Infrared Fluorophore Sensitive to the Full Amyloid Beta Aggregation Pathway"],"prefix":"10.1021","volume":"147","author":[{"given":"Zeming","family":"Wang","sequence":"first","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7819-2861","authenticated-orcid":true,"given":"Line G.","family":"Kristensen","sequence":"additional","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]},{"name":"Division of Molecular Biophysics & Integrated Bioimaging","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen H.","family":"Ho","sequence":"additional","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]},{"name":"Department of Chemistry","place":["Berkeley, United States"]},{"name":"University of California","place":["Berkeley, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazhi","family":"Liu","sequence":"additional","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis A.","family":"Valencia","sequence":"additional","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isha","family":"Nadig","sequence":"additional","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4333-7539","authenticated-orcid":true,"given":"Kyleigh L.","family":"Range","sequence":"additional","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]},{"name":"Department of Biological Sciences, California State University, East Bay, Hayward, California 94542, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6531-9168","authenticated-orcid":true,"given":"Behzad","family":"Rad","sequence":"additional","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7899-0951","authenticated-orcid":true,"given":"Corie Y.","family":"Ralston","sequence":"additional","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]},{"name":"Division of Molecular Biophysics & Integrated Bioimaging","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3655-3638","authenticated-orcid":true,"given":"Bruce E.","family":"Cohen","sequence":"additional","affiliation":[{"name":"The Molecular Foundry","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]},{"name":"Division of Molecular Biophysics & Integrated Bioimaging","place":["Berkeley, United States"]},{"name":"Lawrence Berkeley National Laboratory","place":["Berkeley, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,5,23]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-021-01249-0"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c01122"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms11915"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2868-18.2019"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2101"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1799"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1126\/science.1079469"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2116736119"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3390\/biophysica2020010"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00731"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2000223117"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2020.12.012"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-062920-063704"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2022.01.011"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2020.09.003"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa6760"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpc.2021.106711"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.5b01259"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2022.06.031"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2023.102926"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2010.02.001"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M210207200"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2022.11.1764"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/C4MT00323C"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.9b00199"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.201900054"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.9b00404"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/pro.5560020312"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1080\/13506129.2017.1304905"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1039\/C6CC02741E"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b06190"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b10809"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b06966"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA120.015327"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.6b00517"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2009.11.002"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/319070a0"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(87)90157-6"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201914263"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202107943"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1039\/D2SC05004H"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1126\/science.1069346"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/jp0709104"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409469102"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.0c00276"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2022.03.020"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC09345G"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1039\/C7CC04323F"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.7b00748"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3256"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/ja043919h"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b04782"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-020-0909-6"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/jo061369v"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(89)90046-8"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1098\/rsos.160696"},{"key":"ref57\/cit57","volume-title":"Principles of Fluorescence Spectroscopy","author":"Lakowicz J. R.","year":"2017"},{"key":"ref58\/cit58","first-page":"20","volume-title":"Methods in Enzymology","volume":"413","author":"Teplow D. B.","year":"2006"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2018.09.017"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05577-8"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-020-00554-5"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c11181"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.optmat.2018.07.031"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c07856"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2818.1993.tb03313.x"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.2174\/187152710791012071"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1126\/science.aao2825"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1021\/jp910077h"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12683-8"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.5c01512","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.5c01512","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T04:16:35Z","timestamp":1749010595000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.5c01512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,23]]},"references-count":69,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2025,6,4]]}},"alternative-id":["10.1021\/jacs.5c01512"],"URL":"https:\/\/doi.org\/10.1021\/jacs.5c01512","relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv-2024-vd53f","asserted-by":"object"}]},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,23]]}}}