{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T03:26:45Z","timestamp":1793158005233,"version":"4.5.0"},"reference-count":35,"publisher":"American Chemical Society (ACS)","issue":"45","license":[{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100007162","name":"Guangdong Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["2024B1212030002"],"award-info":[{"award-number":["2024B1212030002"]}],"id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFB3809900"],"award-info":[{"award-number":["2023YFB3809900"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2023B1515020086"],"award-info":[{"award-number":["2023B1515020086"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020084","name":"Guangzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["2024A03J1055"],"award-info":[{"award-number":["2024A03J1055"]}],"id":[{"id":"10.13039\/501100020084","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004000","name":"Guangzhou Municipal Science and Technology Program key projects","doi-asserted-by":"publisher","award":["2025A04J7045"],"award-info":[{"award-number":["2025A04J7045"]}],"id":[{"id":"10.13039\/501100004000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21704078"],"award-info":[{"award-number":["21704078"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32171319"],"award-info":[{"award-number":["32171319"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32522050"],"award-info":[{"award-number":["32522050"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52403183"],"award-info":[{"award-number":["52403183"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371856"],"award-info":[{"award-number":["82371856"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U22A20156"],"award-info":[{"award-number":["U22A20156"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Guangzhou City","award":["2024D03J0001"],"award-info":[{"award-number":["2024D03J0001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2025,11,12]]},"DOI":"10.1021\/jacs.5c14236","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T19:50:54Z","timestamp":1761853854000},"page":"41800-41808","source":"Crossref","is-referenced-by-count":22,"title":["Bacterial Phospholipid-Inducible Helix-Transformable Antimicrobial Polypeptides"],"prefix":"10.1021","volume":"147","author":[{"given":"Xinshuang","family":"Zhang","sequence":"first","affiliation":[{"name":"School of Biomedical Sciences and Engineering","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]},{"name":"National Engineering Research Centre for Tissue Restoration and Reconstruction and Key Laboratory of Biomedical Engineering of Guangdong Province, and Innovation Centre for Tissue Restoration and Reconstruction","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9711-2070","authenticated-orcid":true,"given":"Dong","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]},{"name":"National Engineering Research Centre for Tissue Restoration and Reconstruction and Key Laboratory of Biomedical Engineering of Guangdong Province, and Innovation Centre for Tissue Restoration and Reconstruction","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongqing","family":"Xia","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Hubei Key Laboratory of Plasma Chemistry and Advanced Materials","place":["Wuhan, P. R. China"]},{"name":"Wuhan Institute of Technology","place":["Wuhan, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kangxiu","family":"Wu","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital","place":["Guangzhou, P. R. China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, P. R. China"]},{"name":"Department of Clinical Laboratory, Sun Yat-Sen Memorial Hospital","place":["Guangzhou, P. R. China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyi","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]},{"name":"National Engineering Research Centre for Tissue Restoration and Reconstruction and Key Laboratory of Biomedical Engineering of Guangdong Province, and Innovation Centre for Tissue Restoration and Reconstruction","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxian","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]},{"name":"National Engineering Research Centre for Tissue Restoration and Reconstruction and Key Laboratory of Biomedical Engineering of Guangdong Province, and Innovation Centre for Tissue Restoration and Reconstruction","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huosheng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital","place":["Guangzhou, P. R. China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Hu","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]},{"name":"National Engineering Research Centre for Tissue Restoration and Reconstruction and Key Laboratory of Biomedical Engineering of Guangdong Province, and Innovation Centre for Tissue Restoration and Reconstruction","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songyin","family":"Huang","sequence":"additional","affiliation":[{"name":"Center for Biotherapy, Sun Yat-Sen Memorial Hospital","place":["Guangzhou, P. R. China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, P. R. China"]},{"name":"Guangdong Provincial Key Laboratory of Cancer Pathogenesis and Precision Diagnosis and Treatment, Shenshan Medical Center, Sun Yat-Sen Memorial Hospital","place":["Shanwei, P. R. China"]},{"name":"Sun Yat-Sen University","place":["Shanwei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyi","family":"Jia","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]},{"name":"National Engineering Research Centre for Tissue Restoration and Reconstruction and Key Laboratory of Biomedical Engineering of Guangdong Province, and Innovation Centre for Tissue Restoration and Reconstruction","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengrun","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]},{"name":"National Engineering Research Centre for Tissue Restoration and Reconstruction and Key Laboratory of Biomedical Engineering of Guangdong Province, and Innovation Centre for Tissue Restoration and Reconstruction","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5072-9428","authenticated-orcid":true,"given":"Yan","family":"Bao","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital","place":["Guangzhou, P. R. China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houbing","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]},{"name":"Key Laboratory of Biomedical Engineering of Guangdong Province, and Innovation Centre for Tissue Restoration and Re-Construction","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Zhao","sequence":"additional","affiliation":[{"name":"School of Life Science and Medicine","place":["Hefei, P. R. China"]},{"name":"University of Science and Technology of China","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Cai","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Hubei Key Laboratory of Plasma Chemistry and Advanced Materials","place":["Wuhan, P. R. China"]},{"name":"Wuhan Institute of Technology","place":["Wuhan, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0020-5965","authenticated-orcid":true,"given":"Menghua","family":"Xiong","sequence":"additional","affiliation":[{"name":"School of Biomedical Sciences and Engineering","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]},{"name":"National Engineering Research Centre for Tissue Restoration and Reconstruction and Key Laboratory of Biomedical Engineering of Guangdong Province, and Innovation Centre for Tissue Restoration and Reconstruction","place":["Guangzhou, P. R. China"]},{"name":"South China University of Technology","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,10,30]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-022-00991-2"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-51933-2"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-019-0058-8"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-025-01200-y"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-024-01045-x"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.93267"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adt8239"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1039\/D3SC04523D"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1039\/D1SC03597E"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aaz6333"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-020-0723-z"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1126\/science.aau5480"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1186\/s40779-021-00343-2"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11101417"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s44222-024-00152-x"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37003-z"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-023-01524-6"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30327-3"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2017.138"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-020-0529-6"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3390\/biomimetics6010003"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-060713-035324"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2020.12.016"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00095F"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.202300480"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-17736-x"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b01831"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.9b01052"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adn9435"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2025.123392"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2025.123564"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202001308"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.08.001"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.202300236"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11121772"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.5c14236","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.5c14236","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T09:43:24Z","timestamp":1762940604000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.5c14236"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,30]]},"references-count":35,"journal-issue":{"issue":"45","published-print":{"date-parts":[[2025,11,12]]}},"alternative-id":["10.1021\/jacs.5c14236"],"URL":"https:\/\/doi.org\/10.1021\/jacs.5c14236","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,30]]}}}