{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T19:45:56Z","timestamp":1793303156948,"version":"4.5.0"},"reference-count":73,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100009076","name":"University of Science and Technology of China","doi-asserted-by":"publisher","award":["YD2060006006"],"award-info":[{"award-number":["YD2060006006"]}],"id":[{"id":"10.13039\/501100009076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["WK2490250006"],"award-info":[{"award-number":["WK2490250006"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["YSBR-094"],"award-info":[{"award-number":["YSBR-094"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China (973 Program)","doi-asserted-by":"crossref","award":["2024YFA1509203"],"award-info":[{"award-number":["2024YFA1509203"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["52233009"],"award-info":[{"award-number":["52233009"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["52303213"],"award-info":[{"award-number":["52303213"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["52350348"],"award-info":[{"award-number":["52350348"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["52425306"],"award-info":[{"award-number":["52425306"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["52573180"],"award-info":[{"award-number":["52573180"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["92356302"],"award-info":[{"award-number":["92356302"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2026,3,25]]},"DOI":"10.1021\/jacs.5c19856","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T06:00:23Z","timestamp":1773640823000},"page":"11667-11682","source":"Crossref","is-referenced-by-count":11,"title":["Photocatalytic Activation Strategy for Sequential Prodrug Release to Overcome Resistant Biofilms"],"prefix":"10.1021","volume":"148","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3439-869X","authenticated-orcid":true,"given":"Zhiqiang","family":"Shen","sequence":"first","affiliation":[{"name":"Department of Pharmacy, The First Affiliated Hospital of University of Science and Technology of China (USTC), and School of Biomedical Engineering, Division of Life Sciences and Medicine, and Hefei National Research Center for Physical Sciences at the Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]},{"name":"Suzhou Institute for Advanced Research","place":["Suzhou, China"]},{"name":"University of Science and Technology of China","place":["Suzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyuan","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The First Affiliated Hospital of University of Science and Technology of China (USTC), and School of Biomedical Engineering, Division of Life Sciences and Medicine, and Hefei National Research Center for Physical Sciences at the Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haochuan","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The First Affiliated Hospital of University of Science and Technology of China (USTC), and School of Biomedical Engineering, Division of Life Sciences and Medicine, and Hefei National Research Center for Physical Sciences at the Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The First Affiliated Hospital of University of Science and Technology of China (USTC), and School of Biomedical Engineering, Division of Life Sciences and Medicine, and Hefei National Research Center for Physical Sciences at the Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuotao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The First Affiliated Hospital of University of Science and Technology of China (USTC), and School of Biomedical Engineering, Division of Life Sciences and Medicine, and Hefei National Research Center for Physical Sciences at the Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiujun","family":"Ruan","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The First Affiliated Hospital of University of Science and Technology of China (USTC), and School of Biomedical Engineering, Division of Life Sciences and Medicine, and Hefei National Research Center for Physical Sciences at the Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guihai","family":"Gan","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The First Affiliated Hospital of University of Science and Technology of China (USTC), and School of Biomedical Engineering, Division of Life Sciences and Medicine, and Hefei National Research Center for Physical Sciences at the Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9789-6282","authenticated-orcid":true,"given":"Shiyong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The First Affiliated Hospital of University of Science and Technology of China (USTC), and School of Biomedical Engineering, Division of Life Sciences and Medicine, and Hefei National Research Center for Physical Sciences at the Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6969-1343","authenticated-orcid":true,"given":"Jinming","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The First Affiliated Hospital of University of Science and Technology of China (USTC), and School of Biomedical Engineering, Division of Life Sciences and Medicine, and Hefei National Research Center for Physical Sciences at the Microscale","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-022-00791-0"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00986E"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-023-00905-2"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1008"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/417552a"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00807D"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-021-00362-4"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c00523"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c12151"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c10659"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c02324"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000002968"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02646-5"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-023-00866-9"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-022-00357-2"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2019.11.001"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(21)00333-8"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1039\/c2cs15273h"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00779-06"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202219153"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202107155"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/C5SC02769A"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2017.06.021"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201202414"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.0c00337"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.colcom.2021.100371"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/ja5020053"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1039\/b908663n"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c09914"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b05514"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c00663"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202419939"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c04824"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202204526"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/ja5030707"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b04804"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/jo01097a026"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/cr00002a004"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acsphyschemau.3c00045"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/s41929-024-01160-1"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201500088"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1039\/D2PY00414C"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199311113"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/ja062948k"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c04329"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/cr60056a006"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-022-00964-7"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1039\/D4SC02985B"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202207250"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201601708"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.1.317-323.2003"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01312-09"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1562\/2006-04-14-IR-874"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.1991.tb03669.x"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2012.03.023"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00975-09"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkz243"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.40.9.2021"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.6.1761-1770.2001"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00599-06"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.111551898"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-022-00377-3"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-024-01660-y"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c02184"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-43067-8"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1093\/nsr\/nwad269"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201801210"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c03253"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1021\/ja310019x"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-20326-6"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-16177-w"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c03256"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c07372"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.5c19856","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.5c19856","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T08:14:37Z","timestamp":1774426477000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.5c19856"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,16]]},"references-count":73,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,3,25]]}},"alternative-id":["10.1021\/jacs.5c19856"],"URL":"https:\/\/doi.org\/10.1021\/jacs.5c19856","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,16]]}}}