{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T20:31:56Z","timestamp":1781209916351,"version":"3.54.1"},"reference-count":33,"publisher":"American Chemical Society (ACS)","issue":"10","funder":[{"DOI":"10.13039\/100000928","name":"Welch Foundation","doi-asserted-by":"publisher","award":["C1819"],"award-info":[{"award-number":["C1819"]}],"id":[{"id":"10.13039\/100000928","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI055475"],"award-info":[{"award-number":["AI055475"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004917","name":"Cancer Prevention and Research Institute of Texas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004917","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2017,3,15]]},"DOI":"10.1021\/jacs.6b12654","type":"journal-article","created":{"date-parts":[[2017,3,3]],"date-time":"2017-03-03T12:15:48Z","timestamp":1488543348000},"page":"3736-3746","source":"Crossref","is-referenced-by-count":36,"title":["Asymmetric Alkylation of Anthrones, Enantioselective Total Synthesis of (\u2212)- and (+)-Viridicatumtoxins B and Analogues Thereof: Absolute Configuration and Potent Antibacterial Agents"],"prefix":"10.1021","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5332-2511","authenticated-orcid":true,"given":"K. C.","family":"Nicolaou","sequence":"first","affiliation":[{"name":"Department\rof Chemistry, BioScience Research Collaborative and \u2021Department of\rBiochemistry and Cell Biology, Rice University, 6100 Main Street, Houston, Texas 77005, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guodu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, BioScience Research Collaborative and \u2021Department of\rBiochemistry and Cell Biology, Rice University, 6100 Main Street, Houston, Texas 77005, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Beabout","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, BioScience Research Collaborative and \u2021Department of\rBiochemistry and Cell Biology, Rice University, 6100 Main Street, Houston, Texas 77005, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan D.","family":"McCurry","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, BioScience Research Collaborative and \u2021Department of\rBiochemistry and Cell Biology, Rice University, 6100 Main Street, Houston, Texas 77005, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9241-8962","authenticated-orcid":true,"given":"Yousif","family":"Shamoo","sequence":"additional","affiliation":[{"name":"Department\rof Chemistry, BioScience Research Collaborative and \u2021Department of\rBiochemistry and Cell Biology, Rice University, 6100 Main Street, Houston, Texas 77005, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2017,3,3]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2008.84"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(73)90057-4"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2012.83"},{"key":"ref4\/cit4a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201304691"},{"key":"ref4\/cit4b","doi-asserted-by":"publisher","DOI":"10.1021\/ja506472u"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1107\/S0567740882010759"},{"key":"ref6\/cit6a","doi-asserted-by":"publisher","DOI":"10.1021\/ar040063c"},{"key":"ref6\/cit6b","doi-asserted-by":"publisher","DOI":"10.1021\/jo0491004"},{"key":"ref6\/cit6c","doi-asserted-by":"publisher","DOI":"10.1021\/cr020027w"},{"key":"ref6\/cit6d","doi-asserted-by":"publisher","DOI":"10.1021\/cr9409804"},{"key":"ref6\/cit6e","doi-asserted-by":"publisher","DOI":"10.1021\/ar9501129"},{"key":"ref7\/cit7a","doi-asserted-by":"publisher","DOI":"10.1021\/cr020020e"},{"key":"ref7\/cit7b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200601737"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/ja00088a059"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/ja106593m"},{"key":"ref10\/cit10a","doi-asserted-by":"publisher","DOI":"10.1039\/c1sc00137j"},{"key":"ref10\/cit10b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201105536"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/srep16886"},{"key":"ref12\/cit12a","doi-asserted-by":"publisher","DOI":"10.1021\/ja973174y"},{"key":"ref12\/cit12b","doi-asserted-by":"publisher","DOI":"10.1021\/ja9835739"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200462257"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/ja992655+"},{"key":"ref15\/cit15a","doi-asserted-by":"publisher","DOI":"10.1021\/jo00002a074"},{"key":"ref15\/cit15b","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201001175"},{"key":"ref16\/cit16a","doi-asserted-by":"publisher","DOI":"10.1021\/jo060627l"},{"key":"ref16\/cit16b","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2014.09.101"},{"key":"ref17\/cit17a","doi-asserted-by":"publisher","DOI":"10.1039\/c2cc38436a"},{"key":"ref17\/cit17b","doi-asserted-by":"publisher","DOI":"10.1021\/jo0162078"},{"key":"ref17\/cit17c","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201300788"},{"key":"ref18\/cit18a","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2150"},{"key":"ref18\/cit18b","doi-asserted-by":"publisher","DOI":"10.1039\/c3sc50592h"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/ja00252a056"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","unstructured":"Nelson, M.; Hillen, W.; Greenwald, R. A., Eds.Tetracyclines in Biology, Chemistry, and Medicine;Birkh\u00e4user Verlag:Basel, 2001; p26.","DOI":"10.1007\/978-3-0348-8306-1"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6b12654","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T18:13:45Z","timestamp":1682273625000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.6b12654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3,3]]},"references-count":33,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,3,15]]}},"alternative-id":["10.1021\/jacs.6b12654"],"URL":"https:\/\/doi.org\/10.1021\/jacs.6b12654","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,3]]}}}