{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T08:48:19Z","timestamp":1782290899770,"version":"3.54.5"},"reference-count":75,"publisher":"American Chemical Society (ACS)","issue":"24","license":[{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation (NSF)","doi-asserted-by":"crossref","award":["CHE-2246805"],"award-info":[{"award-number":["CHE-2246805"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Case Western Reserve University Expanding Horizons Initiative in the College of Arts and Sciences","award":["2023"],"award-info":[{"award-number":["2023"]}]},{"name":"Case Western Reserve University Expanding Horizons Initiative in the College of Arts and Sciences","award":["2024"],"award-info":[{"award-number":["2024"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2026,6,24]]},"DOI":"10.1021\/jacs.6c00216","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:49:02Z","timestamp":1780966142000},"page":"24695-24710","source":"Crossref","is-referenced-by-count":0,"title":["Development of a Nucleoside Photosensitizer Efficiently Activated by One- or Two-Photon Absorption in the Optical Therapeutic Window"],"prefix":"10.1021","volume":"148","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6001-2156","authenticated-orcid":true,"given":"Sourav Kanti","family":"Seth","sequence":"first","affiliation":[{"name":"Department of Chemistry","place":["Cleveland, United States"]},{"name":"Case Western Reserve University","place":["Cleveland, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8282-7807","authenticated-orcid":true,"given":"Sean J.","family":"Hoehn","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["Cleveland, United States"]},{"name":"Case Western Reserve University","place":["Cleveland, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Acquah","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["Cleveland, United States"]},{"name":"Case Western Reserve University","place":["Cleveland, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liraz","family":"Levi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics","place":["Cleveland, United States"]},{"name":"Case Western Reserve University School of Medicine","place":["Cleveland, United States"]},{"name":"Celloram Inc.","place":["Cleveland, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3594-0890","authenticated-orcid":true,"given":"Carlos E.","family":"Crespo-Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["Cleveland, United States"]},{"name":"Case Western Reserve University","place":["Cleveland, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,6,8]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2292"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/ldl020"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1111\/php.12975"},{"key":"ref4\/cit4","volume-title":"The Selection and Use of Essential Medicines 2023: Report of the 24th WHO Expert Committee on the Selection and Use of Essential Medicines","author":"World Health Organization"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-6147(96)01007-3"},{"key":"ref6\/cit6","unstructured":"Nobel Prize in Physiology or Medicine 1988 - Press\nrelease. NobelPrize.org.\nAvailable at\n                      : https:\/\/www.nobelprize.org\/prizes\/medicine\/1988\/press-release\/. Accessed on 27 Dec 2025."},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/ja510611j"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1039\/c1pp05188a"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC04747C"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13077"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1007\/128_2014_554"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physchem-082423-022427"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22060998"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b07057"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-17333-y"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1039\/D3SC02592F"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201800148"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b07665"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpclett.7b00926"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b06822"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201604543"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(01)00272-X"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-07-0166"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.180"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2011.631978"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201500192"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(71)90409-6"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcatb.2007.04.005"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/S0731-7085(01)00433-2"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202400137"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1194"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-006-0463-x"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.24.10859"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpclett.9b02108"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25030584"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.5c01035"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c13203"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/ar50001a002"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/cr60240a004"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/nenergy.2017.53"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1080\/00268977000100171"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/ja010865s"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/0009-2614(92)85670-6"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0104(93)80253-6"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1063\/1.555680"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1409(199803\/04)2:2<145::AID-JPP60>3.0.CO;2-2"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1912549116"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2203994119"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b09220"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.1999.tb08240.x"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1063\/1.555934"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-4018(01)01121-X"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1364\/OE.24.009053"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1364\/JOSAB.13.000481"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/jp111174p"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1039\/C7SC05448C"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1039\/D4CP03391D"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1039\/D3CP01147J"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.9.000447"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1126\/science.281.5383.1653"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200805257"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1039\/D2CP05186A"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202500718"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1038\/s42004-022-00752-x"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c07967"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-51872-y"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-46768-w"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1039\/D1CS01079D"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c11868"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1021\/cr5004425"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-019-0328-4"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29981-3"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202408594"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2024.215711"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-16993-0"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c00216","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c00216","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T08:12:57Z","timestamp":1782288777000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.6c00216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,8]]},"references-count":75,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2026,6,24]]}},"alternative-id":["10.1021\/jacs.6c00216"],"URL":"https:\/\/doi.org\/10.1021\/jacs.6c00216","relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv.15003530\/v1","asserted-by":"object"}]},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,8]]}}}