{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T09:18:36Z","timestamp":1788254316472,"version":"build-2803163510"},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"33","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","award":["JYB2025XDXM909"],"award-info":[{"award-number":["JYB2025XDXM909"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010040","name":"Taishan Scholar Project of Shandong Province","doi-asserted-by":"publisher","award":["Tstp20250734"],"award-info":[{"award-number":["Tstp20250734"]}],"id":[{"id":"10.13039\/501100010040","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","award":["JCYJ20220818095601002"],"award-info":[{"award-number":["JCYJ20220818095601002"]}],"id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22476126"],"award-info":[{"award-number":["22476126"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U22A20402"],"award-info":[{"award-number":["U22A20402"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Singlet oxygen (1O2) electrosynthesis from dioxygen (O2) offers a sustainable route to value-added oxygenation reactions in pharmaceutical manufacturing. Conventional electrochemical generation, however, relies on the one-electron reduction of O2 to superoxide (O2\u2022\u2013) followed by disproportionation of two O2\u2022\u2013 producing only one molecule of 1O2, which limited to a maximum electron-to-1O2 efficiency at 50%. Here, we overcome this constraint using an electrochemical tandem strategy implemented in a compact flow-through reactor, wherein O2\u2022\u2013 is selectively generated at a modified porous titanium foam cathode and rapidly transported to a titanium-supported platinum single-atom anode for oxidation to 1O2. This design suppresses unproductive pathways, enabling an electron-to-1O2 efficiency exceeding 93%. The system achieves a high 1O2 production rate of 510 \u03bcmol L\u20131 min\u20131, facilitating phosphine oxygenation with 96.2% selectivity and the electrochemical semisynthesis of artemisinin in 44.5% yield. This work establishes a general platform for efficient, continuous 1O2 electrosynthesis, opening avenues for sustainable oxidative manufacturing.<\/jats:p>","DOI":"10.1021\/jacs.6c05962","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:02:01Z","timestamp":1786647721000},"page":"35456-35466","source":"Crossref","is-referenced-by-count":0,"title":["Breaking the 50% Efficiency\nCeiling: A Tandem Electrochemical\nCycle for Efficient Singlet Oxygen Electrosynthesis"],"prefix":"10.1021","volume":"148","author":[{"given":"Long","family":"Zhao","sequence":"first","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Dai","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"University of International Business and Economics , , ,","place":["Beijing, China, 100029"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Chang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingyue","family":"Zou","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxian","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiyuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruizhao","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minzi","family":"Liao","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhao","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6389-9680","authenticated-orcid":true,"given":"Juntao","family":"Ye","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2706-5560","authenticated-orcid":true,"given":"Yancai","family":"Yao","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6842-9167","authenticated-orcid":true,"given":"Lizhi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]},{"name":"Shanghai Jiao Tong University , , ,","place":["Shenzhen, China, 518057"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"issue":"8","key":"2026090104502443300_cit1","doi-asserted-by":"publisher","first-page":"3181","DOI":"10.1039\/b926014p","article-title":"Singlet\nOxygen: There Is Indeed Something New under the Sun","volume":"39","author":"Ogilby","year":"2010","journal-title":"Chem. Soc. Rev."},{"issue":"5610","key":"2026090104502443300_cit2","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1038\/267421a0","article-title":"Singlet Oxygen in\nNatural Waters","volume":"267","author":"Zepp","year":"1977","journal-title":"Nature"},{"issue":"17","key":"2026090104502443300_cit3","doi-asserted-by":"publisher","first-page":"9994","DOI":"10.1021\/acs.chemrev.5b00726","article-title":"Using Singlet Oxygen to Synthesize Natural Products and Drugs","volume":"116","author":"Ghogare","year":"2016","journal-title":"Chem. Rev."},{"issue":"6","key":"2026090104502443300_cit4","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1038\/nchem.2261","article-title":"Applying Green Chemistry to the Photochemical Route\nto Artemisinin","volume":"7","author":"Amara","year":"2015","journal-title":"Nat. Chem."},{"issue":"9","key":"2026090104502443300_cit5","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1021\/ar010086g","article-title":"Reversible Binding\nof Oxygen to Aromatic Compounds","volume":"36","author":"Aubry","year":"2003","journal-title":"Acc. Chem.\nRes."},{"issue":"3","key":"2026090104502443300_cit6","doi-asserted-by":"publisher","first-page":"4204","DOI":"10.1021\/acs.chemrev.1c00686","article-title":"Semiconducting Polymers for Oxygen\nEvolution Reaction under Light Illumination","volume":"122","author":"Fang","year":"2022","journal-title":"Chem. Rev."},{"issue":"49","key":"2026090104502443300_cit7","doi-asserted-by":"publisher","first-page":"17166","DOI":"10.1021\/ja0547026","article-title":"Synergism between Molybdenum and\nLanthanum in the Disproportionation of Hydrogen Peroxide into Singlet\nOxygen","volume":"127","author":"Wahlen","year":"2005","journal-title":"J. Am. Chem. Soc."},{"issue":"21","key":"2026090104502443300_cit8","doi-asserted-by":"publisher","first-page":"5844","DOI":"10.1021\/ja00307a002","article-title":"Search\nfor Singlet Oxygen in the Decomposition of Hydrogen Peroxide by Mineral\nCompounds in Aqueous Solutions","volume":"107","author":"Aubry","year":"1985","journal-title":"J. Am. Chem.\nSoc."},{"issue":"5","key":"2026090104502443300_cit9","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1021\/cr010371d","article-title":"Physical Mechanisms\nof Generation and Deactivation\nof Singlet Oxygen","volume":"103","author":"Schweitzer","year":"2003","journal-title":"Chem. Rev."},{"issue":"47","key":"2026090104502443300_cit10","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202412209","article-title":"Superior Singlet\nOxygen Electrosynthesis via Neighboring Dual Molecular Oxygen Coactivation\nfor Selective Tetracycline Detoxification","volume":"63","author":"Wang","year":"2024","journal-title":"Angew.\nChem., Int. Ed."},{"issue":"1","key":"2026090104502443300_cit11","doi-asserted-by":"publisher","first-page":"5560","DOI":"10.1038\/s41467-022-33149-4","article-title":"Pauling-Type\nAdsorption of O2 Induced Electrocatalytic Singlet Oxygen Production\non N\u2013CuO for Organic Pollutants Degradation","volume":"13","author":"Xie","year":"2022","journal-title":"Nat. Commun."},{"issue":"44","key":"2026090104502443300_cit12","doi-asserted-by":"publisher","first-page":"17123","DOI":"10.1021\/acs.est.3c06336","article-title":"New Insights\ninto Selective Singlet\nOxygen Production via the Typical Electroactivation of Oxygen for\nWater Decontamination","volume":"57","author":"Feng","year":"2023","journal-title":"Environ. Sci. Technol."},{"issue":"6","key":"2026090104502443300_cit13","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1038\/s44160-025-00756-0","article-title":"Compressive-Strained\nRutile TiO2 Enables O2 Mono-Hydrogenation for\nSinglet Oxygen Electrosynthesis","volume":"4","author":"Wang","year":"2025","journal-title":"Nat. Synth."},{"issue":"1","key":"2026090104502443300_cit14","doi-asserted-by":"publisher","first-page":"6228","DOI":"10.1038\/s41467-020-20071-w","article-title":"Janus Electrocatalytic\nFlow-through Membrane Enables Highly Selective Singlet Oxygen Production","volume":"11","author":"Zhao","year":"2020","journal-title":"Nat. Commun."},{"issue":"38","key":"2026090104502443300_cit15","doi-asserted-by":"publisher","first-page":"20860","DOI":"10.1021\/acs.est.5c08644","article-title":"Harnessing\nSpatiotemporal Interaction\nof Redox Reactions Boosts Singlet Oxygen Generation in Electrocatalytic\nDual-Membrane Systems","volume":"59","author":"Gu","year":"2025","journal-title":"Environ. Sci. Technol."},{"issue":"3","key":"2026090104502443300_cit16","doi-asserted-by":"publisher","first-page":"031004","DOI":"10.1088\/2515-7655\/abe039","article-title":"A Discussion on\nthe Possible Involvement of Singlet Oxygen in Oxygen Electrocatalysis","volume":"3","author":"Chen","year":"2021","journal-title":"J. Phys. Energy"},{"issue":"20","key":"2026090104502443300_cit17","doi-asserted-by":"publisher","first-page":"12445","DOI":"10.1021\/acs.chemrev.1c00139","article-title":"Singlet Oxygen\nin Electrochemical Cells: A Critical Review of Literature and Theory","volume":"121","author":"Schu\u0308rmann","year":"2021","journal-title":"Chem. Rev."},{"issue":"1","key":"2026090104502443300_cit18","doi-asserted-by":"publisher","first-page":"8696","DOI":"10.1038\/ncomms9696","article-title":"Defective Titanium\nDioxide Single Crystals Exposed\nby High-Energy {001} Facets for Efficient Oxygen Reduction","volume":"6","author":"Pei","year":"2015","journal-title":"Nat. Commun."},{"issue":"41","key":"2026090104502443300_cit19","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202208215","article-title":"Single Atom\nRu Monolithic Electrode for Efficient Chlorine Evolution and Nitrate\nReduction","volume":"61","author":"Yao","year":"2022","journal-title":"Angew. Chem., Int. Ed."},{"issue":"26","key":"2026090104502443300_cit20","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202505718","article-title":"Precise Engineering\nof Asymmetric Tri-Active Sites by Symbiotic Strategy for Photocontrolled\nDirectional Reforming of Biomass","volume":"64","author":"Yan","year":"2025","journal-title":"Angew. Chem.,\nInt. Ed."},{"issue":"1","key":"2026090104502443300_cit21","doi-asserted-by":"publisher","first-page":"5990","DOI":"10.1038\/s41467-024-50332-x","article-title":"Spin Occupancy\nRegulation of the Pt D-Orbital for a Robust Low-Pt Catalyst towards\nOxygen Reduction","volume":"15","author":"Xue","year":"2024","journal-title":"Nat. Commun."},{"issue":"1","key":"2026090104502443300_cit22","doi-asserted-by":"publisher","first-page":"2608","DOI":"10.1038\/s41467-021-22865-y","article-title":"Spin-Polarized Oxygen Evolution Reaction under Magnetic Field","volume":"12","author":"Ren","year":"2021","journal-title":"Nat. Commun."},{"issue":"1","key":"2026090104502443300_cit23","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1038\/s41467-023-44469-4","article-title":"Spin Polarized\nFe1\u2013Ti Pairs for Highly Efficient Electroreduction\nNitrate to Ammonia","volume":"15","author":"Dai","year":"2024","journal-title":"Nat. Commun."},{"issue":"16","key":"2026090104502443300_cit24","doi-asserted-by":"publisher","first-page":"11152","DOI":"10.1021\/jacs.3c13834","article-title":"Engineering the Coordination\nEnvironment of Ir Single Atoms with Surface Titanium Oxide Amorphization\nfor Superior Chlorine Evolution Reaction","volume":"146","author":"Wang","year":"2024","journal-title":"J.\nAm. Chem. Soc."},{"issue":"1","key":"2026090104502443300_cit25","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1038\/s41467-024-45367-z","article-title":"Distribution of Pt\nSingle Atom Coordination Environments on Anatase TiO2 Supports\nControls Reactivity","volume":"15","author":"Zang","year":"2024","journal-title":"Nat. Commun."},{"issue":"8","key":"2026090104502443300_cit26","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1038\/nchem.1095","article-title":"Single-Atom Catalysis\nof CO Oxidation Using Pt1\/FeOx","volume":"3","author":"Qiao","year":"2011","journal-title":"Nat. Chem."},{"issue":"7","key":"2026090104502443300_cit27","doi-asserted-by":"publisher","first-page":"4030","DOI":"10.1021\/acscatal.2c06081","article-title":"Pt3Ti Intermetallic\nAlloy Formed by Strong Metal\u2013Support Interaction over Pt\/TiO2 for the Selective Hydrogenation of Acetophenone","volume":"13","author":"Zhang","year":"2023","journal-title":"ACS Catal."},{"issue":"5","key":"2026090104502443300_cit28","doi-asserted-by":"publisher","first-page":"17036","DOI":"10.1038\/nenergy.2017.36","article-title":"Singlet Oxygen Generation as a Major\nCause for Parasitic\nReactions during Cycling of Aprotic Lithium\u2013Oxygen Batteries","volume":"2","author":"Mahne","year":"2017","journal-title":"Nat. Energy"},{"issue":"3","key":"2026090104502443300_cit29","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1021\/ja00758a071","article-title":"Remarkable Solvent Effects on the Lifetime of 1\u0394g Oxygen","volume":"94","author":"Merkel","year":"1972","journal-title":"J. Am. Chem.\nSoc."},{"issue":"11","key":"2026090104502443300_cit30","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1039\/b914074c","article-title":"Strategies for Cleaner\nOxidations Using Photochemically Generated Singlet Oxygen in Supercritical\nCarbon Dioxide","volume":"11","author":"Han","year":"2009","journal-title":"Green Chem."},{"issue":"4","key":"2026090104502443300_cit31","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1021\/jo048518z","article-title":"Assignment of the EPR Spectrum of 5,5-Dimethyl-1-Pyrroline N-Oxide\n(DMPO) Superoxide Spin Adduct","volume":"70","author":"Cle\u0301ment","year":"2005","journal-title":"J. Org. Chem."},{"key":"2026090104502443300_cit32","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.aca.2013.07.027","article-title":"Superoxide Generated\nby Pyrogallol Reduces Highly Water-Soluble Tetrazolium Salt to Produce\na Soluble Formazan: A Simple Assay for Measuring Superoxide Anion\nRadical Scavenging Activities of Biological and Abiological Samples","volume":"793","author":"Xu","year":"2013","journal-title":"Anal. Chim. Acta"},{"issue":"39","key":"2026090104502443300_cit33","doi-asserted-by":"publisher","first-page":"12855","DOI":"10.1002\/anie.201804978","article-title":"Adsorbed Intermediates in Oxygen\nReduction on Platinum Nanoparticles Observed by In Situ IR Spectroscopy","volume":"57","author":"Nayak","year":"2018","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026090104502443300_cit34","doi-asserted-by":"publisher","first-page":"140312","DOI":"10.1016\/j.cej.2022.140312","article-title":"Rotating Ring-Disk\nElectrode Method to Evaluate Performance of Electrocatalysts in Hydrogen\nPeroxide Activation via Rapid Detection of Hydroxyl Radicals","volume":"454","author":"Wen","year":"2023","journal-title":"Chem. Eng. J."},{"issue":"4","key":"2026090104502443300_cit35","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1039\/D2EE03930C","article-title":"Adjacent Fe Site Boosts\nElectrocatalytic Oxygen Evolution at Co Site in Single-Atom-Catalyst\nthrough a Dual-Metal-Site Design","volume":"16","author":"Chen","year":"2023","journal-title":"Energy Environ.\nSci."},{"issue":"16","key":"2026090104502443300_cit36","doi-asserted-by":"publisher","first-page":"4053","DOI":"10.1016\/S0021-9258(18)62884-4","article-title":"Quantitative\nAspects of the Production of Superoxide Anion Radical by Milk Xanthine\nOxidase","volume":"245","author":"Fridovich","year":"1970","journal-title":"J. Biol. Chem."},{"issue":"16","key":"2026090104502443300_cit37","doi-asserted-by":"publisher","first-page":"11181","DOI":"10.1021\/jacs.3c14186","article-title":"Second-Shell\nN Dopants Regulate Acidic O2 Reduction Pathways on Isolated\nPt Sites","volume":"146","author":"Ni","year":"2024","journal-title":"J. Am. Chem. Soc."},{"issue":"3","key":"2026090104502443300_cit38","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1021\/acs.chemrev.0c00487","article-title":"Power of Infrared\nand Raman Spectroscopies\nto Characterize Metal-Organic Frameworks and Investigate Their Interaction\nwith Guest Molecules","volume":"121","author":"Hadjiivanov","year":"2021","journal-title":"Chem. Rev."},{"issue":"1","key":"2026090104502443300_cit39","doi-asserted-by":"publisher","first-page":"5716","DOI":"10.1038\/s41467-025-61069-6","article-title":"Full Runner\nElectrolyzer Stack for Industrial-Current-Density NOx\u2013-Mediated Ammonia Synthesis from Air and Water","volume":"16","author":"Liu","year":"2025","journal-title":"Nat. Commun."},{"issue":"1","key":"2026090104502443300_cit40","doi-asserted-by":"publisher","first-page":"117","DOI":"10.3390\/molecules22010117","article-title":"Synthetic\nStrategies for Peroxide Ring Construction in Artemisinin","volume":"22","author":"Vil\u2019","year":"2017","journal-title":"Molecules"},{"issue":"38","key":"2026090104502443300_cit41","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2304562120","article-title":"Highly Selective\nSynthesis of Surface FeIV=O with Nanoscale Zero-Valent\nIron and Chlorite for Efficient Oxygen\nTransfer Reactions","volume":"120","author":"Li","year":"2023","journal-title":"Proc. Natl. Acad. Sci. U.\nS. A."},{"issue":"10","key":"2026090104502443300_cit42","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202519699","article-title":"Electron Transfer\nMediator\u2013Enabled Modular Control of 1O2 and O2\u2022\u2013 Generation in Porphyrin\nSupramolecular Frameworks for Selective Photosynthesis","volume":"65","author":"Liu","year":"2026","journal-title":"Angew. Chem., Int. Ed."},{"issue":"9","key":"2026090104502443300_cit43","doi-asserted-by":"publisher","first-page":"2870","DOI":"10.1039\/D0EE01114B","article-title":"Suppressing Singlet Oxygen Generation\nin Lithium\u2013Oxygen Batteries with Redox Mediators","volume":"13","author":"Liang","year":"2020","journal-title":"Energy Environ. Sci."},{"issue":"15","key":"2026090104502443300_cit44","doi-asserted-by":"publisher","first-page":"5183","DOI":"10.1021\/ja00770a006","article-title":"Mechanism of Quenching of Singlet Oxygen by Amines","volume":"94","author":"Young","year":"1972","journal-title":"J. Am. Chem. Soc."},{"issue":"6","key":"2026090104502443300_cit45","doi-asserted-by":"publisher","first-page":"3885","DOI":"10.1021\/acs.joc.1c00596","article-title":"Singlet Oxygen Generation from a\nWater-Soluble Hypervalent Iodine(V) Reagent AIBX and H2O2: An Access to Artemisinin","volume":"87","author":"Shen","year":"2022","journal-title":"J.\nOrg. Chem."},{"issue":"11","key":"2026090104502443300_cit46","doi-asserted-by":"publisher","first-page":"2005","DOI":"10.1016\/j.tet.2010.01.051","article-title":"A Concise Stereoselective Total Synthesis\nof (+)-Artemisinin","volume":"66","author":"Yadav","year":"2010","journal-title":"Tetrahedron"},{"issue":"3","key":"2026090104502443300_cit47","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1021\/op4003196","article-title":"Semisynthetic Artemisinin,\nthe Chemical Path to Industrial\nProduction","volume":"18","author":"Turconi","year":"2014","journal-title":"Org. Process Res. Dev."},{"issue":"3","key":"2026090104502443300_cit48","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1007\/s11367-010-0151-z","article-title":"Life Cycle\nAssessment of Fine Chemical Production:\nA Case Study of Pharmaceutical Synthesis","volume":"15","author":"Wernet","year":"2010","journal-title":"Int.\nJ. Life Cycle Assess."},{"issue":"2","key":"2026090104502443300_cit49","doi-asserted-by":"publisher","DOI":"10.1002\/amp2.10043","article-title":"Life Cycle\nAssessment and Cost Evaluation of Emerging\nTechnologies at Early Stages: The Case of Continuous Flow Synthesis\nof Rufinamide","volume":"2","author":"Grimaldi","year":"2020","journal-title":"J. Adv. Manuf. Process."},{"issue":"11","key":"2026090104502443300_cit50","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1038\/s44160-024-00621-6","article-title":"Upgrading Carbon Monoxide to Bioplastics\nvia Integrated Electrochemical Reduction and Biosynthesis","volume":"3","author":"Wi","year":"2024","journal-title":"Nat. Synth."}],"container-title":["Journal of the American\nChemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c05962","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/33\/35456\/66534333\/jacs.6c05962.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jacsat\/article-pdf\/148\/33\/35456\/66534333\/jacs.6c05962.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T08:50:27Z","timestamp":1788252627000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jacsat\/article\/148\/33\/35456\/5254736\/Breaking-the-50-Efficiency-Ceiling-A-Tandem"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,13]]},"references-count":50,"journal-issue":{"issue":"33","published-online":{"date-parts":[[2026,8,13]]},"published-print":{"date-parts":[[2026,8,26]]}},"URL":"https:\/\/doi.org\/10.1021\/jacs.6c05962","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,13]]}}}