{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:02:44Z","timestamp":1790830964827,"version":"4.1.0"},"reference-count":65,"publisher":"American Chemical Society (ACS)","issue":"22","license":[{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T00:00:00Z","timestamp":1779667200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC3402800"],"award-info":[{"award-number":["2023YFC3402800"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2018R1A3B1052702"],"award-info":[{"award-number":["2018R1A3B1052702"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2025-16652968"],"award-info":[{"award-number":["RS-2025-16652968"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M761096"],"award-info":[{"award-number":["2024M761096"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2662025SYPY005"],"award-info":[{"award-number":["2662025SYPY005"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Natural Science Foundation of Hubei Province","award":["2022CFA033"],"award-info":[{"award-number":["2022CFA033"]}]},{"name":"Open Project Program of Wuhan National Laboratory for Optoelectronics","award":["2024WNLIKF001"],"award-info":[{"award-number":["2024WNLIKF001"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["22022404"],"award-info":[{"award-number":["22022404"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["22374055"],"award-info":[{"award-number":["22374055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["22474047"],"award-info":[{"award-number":["22474047"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["82120108016"],"award-info":[{"award-number":["82120108016"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["U24A6012"],"award-info":[{"award-number":["U24A6012"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["U25A20592"],"award-info":[{"award-number":["U25A20592"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Key Laboratory of Nano-imaging and Drug-loaded Preparation of Shanxi Province","award":["202104010910010"],"award-info":[{"award-number":["202104010910010"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Am. Chem. Soc."],"published-print":{"date-parts":[[2026,6,10]]},"DOI":"10.1021\/jacs.6c06618","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T01:59:08Z","timestamp":1779760748000},"page":"23254-23267","source":"Crossref","is-referenced-by-count":6,"title":["DNA-Targeted Sonodynamic Activation Enhances Antibacterial Efficacy in Deep and Hypoxic Infections"],"prefix":"10.1021","volume":"148","author":[{"given":"Yuling","family":"Xu","sequence":"first","affiliation":[{"name":"The Radiology Department of First Hospital of Shanxi Medical University","place":["Taiyuan, China"]},{"name":"Department of Chemistry","place":["Seoul, Korea"]},{"name":"Korea University","place":["Seoul, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Yan","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Biomedicine and Health","place":["Wuhan, China"]},{"name":"Huazhong Agricultural University","place":["Wuhan, China"]},{"name":"College of Chemistry","place":["Wuhan, China"]},{"name":"Central China Normal University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2175-098X","authenticated-orcid":true,"given":"Chonglu","family":"Li","sequence":"additional","affiliation":[{"name":"College of Chemistry","place":["Wuhan, China"]},{"name":"Central China Normal University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihui","family":"Zhao","sequence":"additional","affiliation":[{"name":"Wuhan Pulmonary Hospital (Wuhan Institute for Tuberculosis Control)","place":["Wuhan, China"]},{"name":"Hubei Branch (Wuhan Pulmonary Hospital) of the National Clinical Research Center for Infectious Diseases","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longcan","family":"Mei","sequence":"additional","affiliation":[{"name":"College of Chemistry","place":["Wuhan, China"]},{"name":"Central China Normal University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhua","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Chemistry","place":["Wuhan, China"]},{"name":"Central China Normal University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiming","family":"Liang","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Biomedicine and Health","place":["Wuhan, China"]},{"name":"Huazhong Agricultural University","place":["Wuhan, China"]},{"name":"Hubei Jiangxia Laboratory","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3777-2245","authenticated-orcid":true,"given":"Junrong","family":"Li","sequence":"additional","affiliation":[{"name":"College of Chemistry","place":["Wuhan, China"]},{"name":"Central China Normal University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6922-0747","authenticated-orcid":true,"given":"Ruiping","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Radiology Department of First Hospital of Shanxi Medical University","place":["Taiyuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6519-7436","authenticated-orcid":true,"given":"Yao","family":"Sun","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology, College of Biomedicine and Health","place":["Wuhan, China"]},{"name":"Huazhong Agricultural University","place":["Wuhan, China"]},{"name":"Hubei Jiangxia Laboratory","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3477-1172","authenticated-orcid":true,"given":"Jong Seung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["Seoul, Korea"]},{"name":"Korea University","place":["Seoul, Korea"]},{"name":"National Research Laboratory for Convergence Degradation Biology","place":["Seoul, Korea"]},{"name":"Korea University","place":["Seoul, Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,5,25]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)02185-7"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-019-0288-0"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms12010213"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-50805-z"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2011.04.005"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2017-0321TR"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10092064"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00381"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-31479-x"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00173B"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS01051K"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1039\/c5pp00037h"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2016.06.008"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b13507"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1039\/D0NR04540C"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c07262"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c13022"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-024-01809-9"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-30721-w"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1093\/nsr\/nwaf554"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c00659"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1007\/s11426-022-1440-2"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS01370F"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00616G"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201509-650FR"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.0c00156"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1039\/D1CS00403D"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b10176"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-53488-8"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2209904119"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b08667"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-022-00978-z"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202507180"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202319966"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201906823"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-55529-8"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202212259"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.202200597"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c14387"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-25303-1"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1039\/D5CS00088B"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.34133\/bmef.0080"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1039\/D2CC03141H"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1039\/b926014p"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c09470"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-024-01662-5"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2021.10.006"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c02019"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b13399"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-100814-125211"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro884"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2319"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-58723-4"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.05.037"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00211"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-16993-0"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2019.10.004"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1016\/j.euros.2022.04.015"},{"key":"ref59\/cit59","unstructured":"McFarland, S. A. Metal-Based Thiophene Photodynamic Compounds and Their Use. U.S. Patent. US967680B2, 2017."},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00622"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp026"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1039\/C7SC01070B"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-015-1476-7"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6c01526"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.146937"}],"container-title":["Journal of the American Chemical Society"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c06618","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/jacs.6c06618","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T08:29:54Z","timestamp":1781080194000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.6c06618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,25]]},"references-count":65,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2026,6,10]]}},"alternative-id":["10.1021\/jacs.6c06618"],"URL":"https:\/\/doi.org\/10.1021\/jacs.6c06618","relation":{},"ISSN":["0002-7863","1520-5126"],"issn-type":[{"value":"0002-7863","type":"print"},{"value":"1520-5126","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,25]]}}}