{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T15:25:20Z","timestamp":1786548320280,"version":"build-2736575974"},"reference-count":43,"publisher":"American Chemical Society (ACS)","issue":"31","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001459","name":"Ministry of Education - Singapore","doi-asserted-by":"publisher","award":["T2EP50124-0012"],"award-info":[{"award-number":["T2EP50124-0012"]}],"id":[{"id":"10.13039\/501100001459","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001381","name":"National Research Foundation Singapore","doi-asserted-by":"publisher","award":["NRF-CRP27-2021-0004"],"award-info":[{"award-number":["NRF-CRP27-2021-0004"]}],"id":[{"id":"10.13039\/501100001381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001381","name":"National Research Foundation Singapore","doi-asserted-by":"publisher","award":["NRF-CRP31-0047"],"award-info":[{"award-number":["NRF-CRP31-0047"]}],"id":[{"id":"10.13039\/501100001381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001381","name":"National Research Foundation Singapore","doi-asserted-by":"publisher","award":["NRFF13-2021-0007"],"award-info":[{"award-number":["NRFF13-2021-0007"]}],"id":[{"id":"10.13039\/501100001381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001352","name":"National University of Singapore","doi-asserted-by":"publisher","award":["CHI-P2024-03"],"award-info":[{"award-number":["CHI-P2024-03"]}],"id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Activation of saturated C\u2013H bonds, particularly the partial oxidation of methyl groups, remains a major challenge in modern catalysis due to their high bond dissociation energies and low polarity, and it currently relies heavily on costly catalysts, oxidants, and harsh conditions. In this work, we report a sustainable strategy for the selective partial oxidation of methyl groups using electrochemically generated ceric ions (Ce4+). Using toluene as a model system, we construct a Pickering emulsion stabilized by hydrophobized SiO2 microspheres, which markedly increases the interfacial area between the organic toluene phase and the aqueous Ce4+ phase. As a result, the system achieves a high benzaldehyde selectivity (\u223c80%) with a production rate of \u223c10 mM h\u20131, nearly a 2-fold enhancement compared with a nonemulsified biphasic system. The reduced Ce3+ species is efficiently regenerated via electrochemical oxidation with a high electron utilization efficiency exceeding 95%, enabling a closed-loop oxidation\u2013regeneration cycle under mild conditions. We also demonstrate that the solid emulsifier can be readily recovered and reused for ten cycles without noticeable performance degradation. Moreover, we extend this strategy to a broad range of aromatic and aliphatic methyl-containing substrates, demonstrating its broad applicability. When powered by renewable electricity, the process provides a green and cost-effective alternative to conventional methyl oxidation routes.<\/jats:p>","DOI":"10.1021\/jacs.6c06758","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:35:06Z","timestamp":1785854106000},"page":"33263-33273","source":"Crossref","is-referenced-by-count":0,"title":["Selective\nPartial Oxidation of Methyl Groups by Electrochemically\nGenerated Ceric Ions"],"prefix":"10.1021","volume":"148","author":[{"given":"Hongling","family":"Huang","sequence":"first","affiliation":[{"name":"National University of Singapore , , 4 Engineering Drive 4 , ,","place":["Singapore, Singapore, 117585"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9556-3735","authenticated-orcid":true,"given":"Weidong","family":"Zhang","sequence":"additional","affiliation":[{"name":"National University of Singapore , , 9 Engineering Drive 1 , ,","place":["Singapore, Singapore, 117575"]},{"name":"National University of Singapore , , 1 Engineering Drive 3 , ,","place":["Singapore, Singapore, 117580"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5156-4493","authenticated-orcid":true,"given":"Xianwen","family":"Mao","sequence":"additional","affiliation":[{"name":"National University of Singapore , , 9 Engineering Drive 1 , ,","place":["Singapore, Singapore, 117575"]},{"name":"National University of Singapore , , 1 Engineering Drive 3 , ,","place":["Singapore, Singapore, 117580"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bihao","family":"Hu","sequence":"additional","affiliation":[{"name":"National University of Singapore , , 4 Engineering Drive 4 , ,","place":["Singapore, Singapore, 117585"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1931-7767","authenticated-orcid":true,"given":"Lei","family":"Wang","sequence":"additional","affiliation":[{"name":"National University of Singapore , , 4 Engineering Drive 4 , ,","place":["Singapore, Singapore, 117585"]},{"name":"National University of Singapore , , 1 Engineering Drive 3 , ,","place":["Singapore, Singapore, 117580"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,1]]},"reference":[{"issue":"1","key":"2026081210101477000_cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-49005-6","article-title":"Photocatalytic\ntoluene oxidation with nickel-mediated cascaded active units over\nNi\/Bi2WO6 monolayers","volume":"15","author":"Shi","year":"2024","journal-title":"Nat. Commun."},{"issue":"51","key":"2026081210101477000_cit2","doi-asserted-by":"publisher","first-page":"21888","DOI":"10.1021\/acs.est.3c06782","article-title":"Local electron environment\nregulation\nof spinel CoMn2O4 induced effective reactant\nadsorption and transformation of lattice oxygen for toluene oxidation","volume":"57","author":"Dong","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"2026081210101477000_cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.149776","article-title":"Mn-based catalysts\nderived from the non-thermal treatment of Mn-MIL-100 to enhance its\nwater-resistance for toluene oxidation: Mechanism study","volume":"485","author":"Bi","year":"2024","journal-title":"Chem. Eng. J."},{"issue":"1","key":"2026081210101477000_cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s43586-021-00041-2","article-title":"C\u2013H activation","volume":"1","author":"Rogge","year":"2021","journal-title":"Nat. Rev. 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